Today, CancerBro will explain testicular cancer staging in a detailed and easy to understand manner. Also, read more about Testicular cancer staging explained in a detailed and easy manner HERE. https://www.cancerbro.com/testicular-cancer-staging/ Video Transcript: Now we come to the staging of testicular tumors. It can be divided into 3 stages. Stage 1 includes patients with disease limited to the testis. It may be T1 to T4 depending upon the extent of testicular involvement as we have discussed previously. In this stage the disease has not spread outside the testis, that is N0 and M0 also the serum tumor markers are normal, that is S0. Rarely, the tumor markers may be elevated in stage 1, when it is called as stage 1S. So stage 1 is the disease which is limited to the testis without any spread elsewhere, with serum tumor markers normal, except in 1 S. Stage 2 includes patients with disease limited to the testis and regional lymph nodes, but there is no spread of the disease to non regional lymph nodes or any other organs. The markers may be S0 or S1. As you can see in the figure, stage 2 is the disease limited to the testis and regional or retroperitoneal lymph nodes, without any spread of the disease elsewhere. The markers may be normal or they might be elevated, that is S0 or S1. It may be stage 2A, 2B or 2C depending upon whether the lymph nodes are N1, N2 or N3, respectively, according to the size and number of lymph nodes. And stage 3 includes patients with disease spread to non-regional lymph nodes or other organs, that is M1a or M1b, or those patients with markers highly elevated, that is S2 or S3. For example, mediastinal lymph node involvement. Or supraclavicular lymph node involvement. Or involvement ot inguinal lymph nodes. Stage 3 also includes patients with spread to lungs or pulmonary metastasis. Spread to the liver or spread to brain or bones, as diagnosed by MRI brain or bone scan. Also, regional or retroperitoneal lymph node involvement with markers highly elevated, that is in S2 and S3 range, also comes under stage 3. So with this, we finish the staging for testicular cancer. CancerBro is also active on social media channels. Follow him to get rich and authoritative content related to cancer awareness, risk factors, symptoms, diagnosis, treatment, etc. Facebook - https://www.facebook.com/officialcancerbro Instagram - https://www.instagram.com/official_cancerbro Twitter - https://twitter.com/cancer_bro/ Website - http://www.cancerbro.com/
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Today, CancerBro will explain TNM testicular cancer staging. Watch the video to better understand the TNM staging system of testicular cancer. Also, read more about TNM testicular cancer staging HERE. https://www.cancerbro.com/testicular-cancer-staging/ Video Transcript: So after discussing the normal anatomy of the testis, we now come to the T staging for testicular tumors. This figure shows the T1 stage in which the tumor is limited to the testis. It may invade the tunica albuginea but not the tunica vaginalis. There is no lymphovascular invasion by the tumor. In this figure also we see the T1 disease, which is localised to the testis, not invading tunica vaginalis. Next comes the T2 disease. In this, the disease is limited to the testis or epididymis. The tumor may extend through tunica albuginea to involve tunica vaginalis, or there might be lymphovascularinvasion by the tumor. This figure also shows the T2 disease, with infiltration of the tumor into the tunica vaginalis. This figure shows T3 disease in which the tumor infiltrates into the spermatic cord. And here the tumor infiltrates into the scrotum, called as T4. So after the T staging, comes the N staging or the nodal staging. Absence of regional lymph nodes is called as N0, whereas, involvement of regional lymph nodes is called as N1, N2 or N3 depending upon the size and the number of the nodes. These nodal structures called as retroperitoneal lymph nodes are the regional lymph nodes for testicular cancer. Their size and number determines the N-stage, that is N1, N2 or N3. After the T and N staging, comes the M staging for testicular cancer. It is called as M1a if there is spread to non regional lymph nodes, that is, any nodes except retroperitoneal lymph nodes as discussed above, or if there is spread to lungs that is called as pulmonary metastasis. Whereas spread to the organs than lungs is called as M1b. This figure shows M1a disease due to the involvement of lymph nodes in the mediastinum, this is non regional lymph nodes because it is outside the retroperitoneum. Similarly, involvement of inguinal lymph nodes is also M1a disease because it is a non-regional lymph nodes for testis. And here, involvement of supraclavicular lymph node is non-regional. M1a disease also includes the cases with pulmonary metastasis, that is spread of the tumor to lungs. Whereas, spread to the organs of the body other than lung is called as M1b. In this figure spread to liver makes it M1b. Spread to brain or bones is also M1b. So with this, we come to the end of TNM classificatiob for testicular cancer.
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Learn more: http://www.ctsnet.org/article/vats-mediastinal-germ-cell-tumor-metastasis-resection
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Cancer of the testicle that has spread to lungs or other distant areas is a sign if it not detected and treated, testicular cancer eventually can lungs, brain, liver, parts body. It may have spread to the lungs or lymph nodes, but has not anywhere else in your body testicular cancer of testis occurs when cells form one both can also invade blood stream and system spread, x ray are done see if chest cavity 12 feb 2016 stage i seminomas these cancers be cured nearly all patients. Testicular cancer potentially spread to lungs testicular info & statistics guide causes, symptoms and treatment options. Testicular cancer stages research uk. Googleusercontent search. M1 there is at least 1 distant metastasis. M1a there is cancer in distant lymph nodes and or the lungs. Has any one here been in this position with a spread to the lungs as i if cancer cells grow and divide many millions of times, tumor can develop. Testicular cancer treatment overview webmdtesticular huntsman institute university of utah testicular symptoms, signs & secondary in the lung macmillan support. Certain types of testicular cancer are can spread through tissue, the lymph system, and blood tissuethe disease is metastatic cancer, not lung i asked if there could be a problem with his thyroid because lump on neck left untreated, to abdomen, neck, lungs 4 jun 2014 retroperitoneal nodes commonest sites for 29 year old male history symptoms clinical presentation tumor cardiac metastasis 20 may 2016 read our article learn more medlineplus. Testicular cancer can usually be cured, even if it has spread when is get detailed information on stage 3 testicular cancer, including treatment options, you have been recently diagnosed, we will review your pathology to confirm iiia these cancers a distant lymph node or the lungs cancerous cells also spread, metastasize, other parts of body and form high tumor markers outside nodes are diagnosed with health professional may (metastasize) lungs, liver, brain, bones. In stage iiic, either the cancer has spread to an organ other than lungs secondary in lung is when cells have from a radiotherapy can help relieve symptoms of i'm feeling very stressed at moment and can't get it out my mind. Mixed germ cell testicular cancer with left ventricular metastasis medlineplus medical encyclopedia. Testicular cancer spread to lungs stage 3 testicular the primer. Testicular cancer treatment (pdq) dana farber institute jordan's story testicular awareness foundation. Testicular cancer stages types testicular url? Q webcache. Information for undertanding testicular cancer. Stage ii testicular cancer has spread (metastasized) to the is lymph nodes in abdomen; Metastasis lung, liver, cells of seminoma patients can be treated with radiation therapy. M0 the disease has not metastasized to distant lymph nodes or other organs. Symptoms in other parts of the body, such as lungs, abdomen, pelvis, back, or brain. Treatment options for testicular cancer, by type and stage. But of
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Radiology reference article management of the primary malignant mediastinal germ cell tumors extragonadal tumor (yolk sac). Gct to the group of poor prognosis germ cell tumors, whatever level tumor markers or 1 jul 2004 abstract. 25 feb 2015 find out about mediastinal germ cell tumours. Cancer printable germ cell tumors of the mediastinum thymus surgical extragonadal involving and treatment (pdq) patient from archives afip. The mediastinum is the most common extragonadal location 2 nov 2015 in which germ cell tumors are foundmediastinal that derive from rest remnants. A germ cell tumour is a that develops from reproductive cells. Background primary mediastinal malignant germ cell tumors (gcts) are rare and have a worse prognosis than their gonadal 25 jan 2010 any anterior mass (figures 1, 2) must be considered suspect for tumor, especially in young male. A variety of extragonadal germ cell tumors are known. Mediastinal germ cell tumor imaging overview, radiography mediastinal tumours cancer teratomas and other tumors of the mediastinum wikipediancbi. Mediastinal germ cell tumours cancer cancerresearchuk mediastinal url? Q webcache. Googleusercontent search. This tumor should be considered strongly in the differential a review of 56 cases primary malignant germ cell tumors mediastinum revealed that, as with benign teratomas, occurred young adults 8 oct 2010 mediastinal are rare, and effect newer drugs treatment strategies this disease on overall survival is not tumours one causes anterior mass, any yolk sac tumourmediastinal mixed 19 feb 2014 (pmmgct) rare sometimes prognosis patients pmmgct very 1 nov abstract. Malignant germ cell tumors of the mediastinumsurvival outcomes for men with mediastinal anterior tumours. Errors in diagnosis tumor markers, was the strongest predictor of improved survival. This study tries to determine the prognostic factors of these tumors 23 jul 2009 my fiance is 29 and was diagnosed with extragonadal mediastinal germ cell tumor (yolk sac) 4 weeks ago. Mediastinal germ cell tumor imaging overview, radiography. Mediastinal germ cell tumors primary mediastinal nonseminomatous results management of malignant tumor the surgical resection non seminomatous. Extragonadal gcts typically arise in 24 may 2016 this includes the pineal gland brain, mediastinum (area if untreated, malignant extragonadal germ cell tumors spread to occur most frequently gonad but can rarely locations, usually or near midline. Mediastinal germ cell tumors are a rare heterogeneous entity. They are sperm cells in 18 nov 2015 germ cell tumors occur most frequently the gonad, but rare cases, they extragonadal locations, usually or near midline. He is on a vent because it has neoplasms exhibiting features of gonadal germ cell arising in the all types tumors (gct) may be seen mediastinum (gcts) are classified as extragonadal if there no evidence primary tumor testes or ovaries. The most common this consensus classification assigns primary mediastinal ns. They most commonly occur in the gonad but occasionally mediastinal germ cell tumors are among common anterior mediastinum. Key words germ cell tumor, mediastinal mass, tumor markers,(j thorac oncol.
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5 year old male child had large lymphnode mass in the superior mediastinum and underwent thoracoscopic lymphnode biopsy. The histopath report confirmed, tuberculosis as the etiology and was treated with anti TB drugs.
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fore more video https://www.youtube.com/channel/UCYf5P5jiDXVg64HI86hPO2Q
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I feel this case might be interesting for you because of its rareness. The patient is 48 years old man. He complained with abdominal pain . About a year ago he fell from a height. CT scan revealed a tumor diameter of 18- 20 cm in retroperitoneal space. We have decided to operate him. During surgery we have found giant tumor with localization the small intestine mesentery. Anatomy was noticeably changed. We took multiple biopsies. Signs of malignization were not found. Intraoperative diagnosis was giant retroperitoneal posttraumatic pseudotumor, actually hematoma. It was very difficult to preserve the integrity of neoplasm. The wall of neoplasm was very thin and tractions were associated with disruptions. Cavity consisted of many septums and contained aseptic liquid. This Intraoperative conditions , Large tumor size also as changed anatomy complicated control of mesenteric vessels. Thats why we removed this neoplasm partially with resection of small intestine and horizontal part of duodenum. . Surgery was finished with duodenojejunostomy. Редкий и интересный случай. Речь идет о 48 летнем мужчине. Пациент жаловался на боли в области живота. В анамнезе падение с высоты. При КТ выявлено новообразование диаметром до 20 см, имевшее ретроперитонеальную локализацию. Мы приняли решение оперировать его. При ревизии брюшной полости было выявлено новообразование брыжейки тонкой кишки. Мы взяли множественную биопсию. Признаков малигнизации найдено не было. Мы рассудили, что имеем дело с гигантской забрюшинной посттравматической псевдоопухолью, фактически гематомой. Полость новообразования состояла из множества септ и содержало асептическую жидкость. Удалить эту опухоль единым целым нам технически не удалось. Минимальное прикосновение вызывало разрыв. Была выполнена резекция тонкой кишки и горизонтальной части двенадцатиперстной , а также удаление опухоли. В принципе, и доброкачественная природа процесса давала возможность парционного удаления, выполнения менее рискованных процедур. Сначала был удален основной компонент, затем остаточный. Далее был сформирован дуоденоэнтероанастомоз.
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Para aortic lymph nodes dissection in a high risk endometrial cancer
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Seminoma CT Axial CECT shows multiple cystic lesions in the para-aortic region. Patient had history of testicular germ cell tumor. Findings are consistent with cystic nodal metastases. The right kidney shows moderate hydronephrosis secondary to mass effect from cystic metastases.
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Visit: http://www.clinicalrobotics.com for further information about the mission and goals of CRSA.
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What is GERMINOMA? What does GERMINOMA mean? GERMINOMA meaning - GERMINOMA definition - GERMINOMA explanation. SUBSCRIBE to our Google Earth flights channel - https://www.youtube.com/channel/UC6UuCPh7GrXznZi0Hz2YQnQ Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/by-sa/3.0/ license. A germinoma is a type of germ cell tumor, which is not differentiated upon examination. It may be benign or malignant. The term germinoma most often refers to a tumor in the brain that has a histology identical to two other tumors: dysgerminoma in the ovary and seminoma in the testis. Since 1994, MeSH has defined germinoma as "a malignant neoplasm of the germinal tissue of the gonads; mediastinum; or pineal region" and within its scope included both dysgerminoma and seminoma. Collectively, these are the seminomatous or germinomatous tumors. Germinomas are thought to originate from an error of development, when certain primordial germ cells fail to migrate properly. Germinomas lack histologic differentiation, whereas nongerminomatous germ cell tumors display a variety of differentiation. Like other germ cell tumors, germinomas can undergo malignant transformation. The tumor is uniform in appearance, consisting of large, round cells with vesicular nuclei and clear or finely granular cytoplasm that is eosinophilic. On gross examination, the external surface is smooth and bosselated (knobby), and the interior is soft, fleshy and either cream-coloured, gray, pink or tan. Microscopic examination typically reveals uniform cells that resemble primordial germ cells. Typically, the stroma contains lymphocytes and about 20% of patients have sarcoid-like granulomas. Metastasis has been noted in approximately 22% of cases at time of diagnosis. Males are approximately twice as commonly affected in developing germinomas. Germinomas are most commonly diagnosed between the ages of 10 and 21. Often serum and spinal fluid tumor markers of AFP and beta-HCG are tested. Pure germinomas are not associated with these markers. Nongerminomatous germ cell tumors may be associated with increased markers such as AFP with yolk sac tumors as well as embryonic cell carcinomas and immature teratomas and beta-HCG which occur in choriocarcinomas. In 1-15% of germinonas a low level of beta-HCG may be produced. Although controversial, there are some thoughts that HCG-secreting germinomas are more aggressive than nonsecreting ones. Dysgerminoma is the most common type of malignant germ cell ovarian cancer. Dysgerminoma usually occurs in adolescence and early adult life; about 5% occur in pre-pubertal children. Dysgerminoma is extremely rare after age 50. Dysgerminoma occurs in both ovaries in 10% of patients and, in a further 10%, there is microscopic tumor in the other ovary. Seminoma is the second most common testicular cancer; the most common is mixed, which may contain seminoma. Abnormal gonads (due to gonadal dysgenesis and androgen insensitivity syndrome) have a high risk of developing a dysgerminoma. Most dysgerminomas are associated with elevated serum lactic dehydrogenase (LDH), which is sometimes used as a tumor marker. Metastases are most often present in the lymph nodes. Intracranial germinoma occurs in 0.7 per million children. As with other germ cell tumors (GCTs) occurring outside the gonads, the most common location of intracranial germinoma is on or near the midline, often in the pineal or suprasellar areas; in 5-10% of patients with germinoma in either area, the tumor is in both areas. Like other (GCTs), germinomas can occur in other parts of the brain. Within the brain, this tumor is most common in the hypothalamic or hypophyseal regions. In the thalamus and basal ganglia, germinoma is the most common GCT. ....
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Chest sonography workshop: malignant lymphadenopathy Gamal Agmy
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Radical resection of hilar cholangiocarcinoma and hilar lymph node dissection come from:http://www.surgbbs.com/
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The mediastinum is an undelineated group of structures in the thorax, surrounded by loose connective tissue. It is the central compartment of the thoracic cavity. It contains the heart, the great vessels of the heart, the esophagus, the trachea, the phrenic nerve, the cardiac nerve, the thoracic duct, the thymus, and the lymph nodes of the central chest. This video is targeted to blind users. Attribution: Article text available under CC-BY-SA Creative Commons image source in video
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Female patient with 10mm mass on the head of the pancreas. The goal of the EUS procedure is to characterise this lesion. Dr Marc Giovannini uses elastography and SonoVue (contrast) and explains how these methods characterise a suspected NET before taking a sample of the mass using a 22ga EchoTip Ultra needle. Prof. Marc Giovannini is a paid consultant for Cook Medical. EchoTip® ProCore™ HD Ultrasound Biopsy Needle. INSTRUCTIONS FOR USE (IFU): https://www.cookmedical.com/data/IFU_PDF/IFU0077-4.PDF MORE INFO: https://www.cookmedical.com/product/-/catalog/echotip-procore-high-definition-ultrasound-biopsy-needle?ds=esc_echoc_webds IMPORTANT INFORMATION: Please review prior to use. INTENDED USE: This device is used with an ultrasound endoscope for fine needle biopsy, (FNB), of submucosal lesions, mediastinal masses, lymph nodes and intraperitoneal masses within or adjacent to the gastrointestinal tract. NOTES: Do not use this device for any purpose other than stated intended use. If package is opened or damaged when received, do not use. Visually inspect with particular attention to kinks, bends and breaks. If an abnormality is detected that would prohibit proper working condition, do not use. Please notify Cook for return authorization. Store in a dry location, away from temperature extremes. Use of this device restricted to a trained healthcare professional. CONTRAINDICATIONS: Those specific to primary endoscopic procedure to be performed in gaining access to desired site. Coagulopathy. POTENTIAL COMPLICATIONS: Those associated with gastrointestinal endoscopy include, but are not limited to: perforation, hemorrhage, aspiration, fever, infection, allergic reaction to medication, hypotension, respiratory depression or arrest, cardiac arrhythmia or arrest, damage to blood vessels, nerve damage, and acute pancreatitis. Those associated with EUS needle biopsy include but are not limited to: pain, death, peritonitis, portal vein gas and thrombosis, pneumoperitoneum and tumor seeding of the needle tract. WARNINGS: Not for use in the heart or vascular system. The tip of the needle and stylet are sharp and could cause injury to the patient or user if not used with caution. PRECAUTIONS: Refer to package label for minimum channel size required for this device. Ensure the stylet is fully inserted when advancing the needle into the biopsy site. When targeting multiple sites, replace device for each site. Needle must be retracted into sheath and thumbscrew on safety ring must be locked to hold needle in place prior to introduction, advancement or withdrawal of device. Failure to retract needle may result in damage to endoscope.
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via YouTube Capture
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A lecture on Neoplasia by Dr. Gerald Abrams, M.D. This lecture was taught as a part of the University of Michigan Medical School's M1 - Patients and Populations Sequence. View the course materials: http://open.umich.edu/education/med/m1/patientspop-genetics/fall2008/materials Creative Commons Attribution-Non Commercial-Share Alike 3.0 License http://creativecommons.org/licenses/by-nc-sa/3.0/ This video has English captions. Help us translate this video: http://www.amara.org/en/v/B5By/
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Learn about the latest in research for advanced breast cancer with two researchers from NCI's Center for Cancer Research, Dr. Stan Lipkowitz, Chief of the Women's Malignancies Branch, and Dr. Alexandra Zimmer, Staff Clinician in the Women's Malignancies Branch. http://www.cancer.gov/socialmediaevents
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As Featured in the EUS app: Download here Android: https://play.google.com/store/apps/details?id=com.eusapp Also available for iPhone and iPad: https://itunes.apple.com/us/app/eus-diagnostic-interventional/id527085806?mt=8
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TRACO 2017 - Introduction and Tumor imaging Air date: Tuesday, September 5, 2017, 4:00:00 PM Category: TRACO Runtime: 01:58:57 Description: Translational Research in Clinical Oncology (TRACO) Recent advances in understanding cancer biology are beginning to be translated into improvements in diagnosis and treatment of cancer. In the post-genome era, we increasingly rely on strong collaboration between basic and clinical scientists to develop novel approaches for treatment of human disease. The NCI Center for Cancer Research (CCR) is one of the largest cancer research organizations in the world, with more than 200 principal investigators, and has played a major role in developing and implementing many new technologies, such as nanotechnology, next generation sequencing, genomics and proteomics. For more information go to http://ccr.cancer.gov/trainee-resources-courses-workshops-traco Author: T. Moody, NCI, NIH and P. Choyke, NCI, NIH Permanent link: https://videocast.nih.gov/launch.asp?23439
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TRACO 2014 - Lymphoma, Prostate Cancer Air date: Monday, September 22, 2014, 4:00:00 PM Category: TRACO Runtime: 02:04:45 Description: TRACO Recent advances in understanding cancer biology are beginning to be translated into improvements in diagnosis and treatment of cancer. In the post-genome era, we increasingly rely on strong collaboration between basic and clinical scientists to develop novel approaches for treatment of human disease. The NCI Center for Cancer Research (CCR) is one of the largest cancer research organizations in the world, with more than 200 principal investigators, and has played a major role in development and implementation of many new technologies, such as nanotechnology, next generation sequencing, genomics and proteomics. For more information go to http://ccr.cancer.gov/careers.courses Author: K. Dunleavy, R. Madan Permanent link: http://videocast.nih.gov/launch.asp?18633
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TRACO 2017: Genomics and Lymphoma Air date: Monday, November 6, 2017, 4:00:00 PM Category: TRACO Runtime: 01:56:04 Description: Translational Research in Clinical Oncology (TRACO) Recent advances in understanding cancer biology are beginning to be translated into improvements in diagnosis and treatment of cancer. In the post-genome era, we increasingly rely on strong collaboration between basic and clinical scientists to develop novel approaches for treatment of human disease. The NCI Center for Cancer Research (CCR) is one of the largest cancer research organizations in the world, with more than 200 principal investigators, and has played a major role in developing and implementing many new technologies, such as nanotechnology, next generation sequencing, genomics and proteomics. For more information go to http://ccr.cancer.gov/training/trainee-resources/courses-workshops/traco Author: Dr. Jun Wei, NCI, NIH and Dr. Kieron Dunleavy, NCI, NIH Permanent link: https://videocast.nih.gov/launch.asp?23572
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