OSTEOPOROSIS DROGS SEVERE PAIN Long-Term Bisphosphonate Use Linked to Abnormal Bone Formation FOSAMAX-ACTONEL-RECLAST-BONIVA
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Millions of women grapple with whether to take bone-density-building drugs to treat or prevent osteoporosis, but the FDA this week warned that long-term use of bisphosphonates can lead to rare fractures and side effects. Margaret Warner and Maine Medical Center's Dr. Clifford Rosen discuss the risks outlined by the FDA.
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side effects of prednisone is used to treat conditions such as arthritis, blood disorders, breathing problems, severe allergies, skin diseases, cancer, eye problems, and immune system disorders. Prednisone long term side effects belongs to a class of drugs known as corticosteroids. It decreases your immune system's response to various diseases to reduce symptoms such as swelling and allergic-type reactions. Prednisone side effects in men may weaken your immune system. A weakened immune system makes you more likely to get infections. More common side effects The more common side effects that occur with prednisone side effects short term include: confusion excitement restlessness headache nausea vomiting thinning skin acne trouble sleeping weight gain severe allergic reactions changes in emotions or moods, such as depression changes in vision eye pain infection, with symptoms such as: fever or chills cough sore throat trouble or pain in passing urine high blood sugar, with symptoms such as: increased thirst passing urine more often feeling sleepy or confused swelling of your ankles or feet The most commonly reported adverse effects associated with corticosteroid use include fluid retention, alteration in glucose tolerance, high blood pressure, behavior and mood changes, increased appetite and weight gain. Side effects of prednisone and other corticosteroids range from mild annoyances to serious, irreversible organ damage, and they occur more frequently with higher doses and more prolonged treatment. Common side effects include: Retention of sodium (salt) and fluid Weight gain on prednisone High blood pressure Loss of potassium Headache Muscle weakness Nausea Vomiting Acne Thinning skin moon face Serious side effects include: Hiccups Puffiness of the face (moon face) Growth of facial hair Thinning and easy bruising of the skin Impaired wound healing Glaucoma Cataracts Ulcers in the stomach and duodenum Worsening of diabetes Irregular menses Rounding of the upper back ("buffalo hump") Obesity Retardation of growth in children Convulsions Anaphylaxis (severe allergic reactions like hives, itching, skin rash, swollen lips/tongue/face) Vision changes Congestive heart failure Heart attack Pulmonary edema Syncope Tachycardia Thrombophlebitis Vasculitis Allergic dermatitis Low blood pressure Amenorrhea (lack of menstruation) Newly onset diabetes Hyperglycemia Hypothyroidism Pancreatitis Anemia Amnesia This drug also causes psychiatric disturbances, which include: what is considered a high dose of prednisone Depression Euphoria Insomnia Mood swings Personality changes Psychotic behavior Other possible serious side effects of this drug include: Prednisone short term dosage and diabetes: is associated with new onset or manifestations of latent diabetes, and worsening of diabetes. Diabetics may require higher doses of diabetes medications while taking. Allergic reaction: Some people may develop a severe allergic reaction (anaphylaxis) to prednisone withdrawal after 5 days that includes swelling of the airways (angioedema) that may result in shortness of breath or airway blockage. Immune suppression: Prednisone 60 mg for 5 days side effects suppresses the immune system and, therefore, increases the frequency or severity of infections and decreases the effectiveness of vaccines and antibiotics. Osteoporosis: Prednisone may cause osteoporosis that results in fractures of bones. Patients taking long-term prednisone often receive supplements of calcium and vitamin D to counteract the effects on bones. Calcium and vitamin D probably are not enough, however, and treatment with bisphosphonates such as alendronate (Fosamax) and risedronate (Actonel) may be necessary. Calcitonin (Miacalcin) also is effective. The development of osteoporosis and the need for treatment can be monitored using bone density scans. Adrenal insufficiency and weaning off prednisone: Prolonged use of prednisone and other corticosteroids causes the adrenal glands to atrophy (shrink) and stop producing the body's natural corticosteroid, cortisol. tapering off prednisone after short term use Necrosis of hips and joints: A serious complication of long-term use of allergic reaction Prednisone is aseptic necrosis of the hip joints. Aseptic necrosis is a condition in which there is death and degeneration of the hip bone. It is a painful condition that ultimately can lead to the need for surgical replacement of the hip. Aseptic necrosis also has been reported in the knee joints. The estimated incidence of aseptic necrosis among long-term users of corticosteroids is 3%-4%. Patients taking corticosteroids who develop pain in the hips or knees should report the pain to their doctors promptly. Patient Advice Medical Disclaimer: It is always advised that Patients should check with their healthcare provider before starting any new medications, including herbal supplements and over the counter products, or receiving any vaccinations.
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2 Important Studies on Fosamax, Actonel & Boniva - NY Attorney Matthew McCauley explains more at: https://www.yourlawyer.com/defective-drug-attorneys/ Watch as Attorney Matthew McCauley of Parker Waichman discusses how 3 major prescription drugs are causing patients to suffer fractures in their leg. For patients who suffer bone diseases like osteoporosis and osteopenia, doctors typically describe a class of drugs known as bisphosphonates. These drugs are manufactured to the public with the brand names of Fosamax, Actonel, and Boniva. Recent studies have shown that these drugs are being linked to femur fractures in patients. Not only are they femur fractures, but something known as "atypical" femur fractures. And what this means is that these breaks aren't being caused by the normal accident or trauma to a leg. Patients are fracturing their femurs doing the most normal of things like getting out of their car or stepping off a curb. One recent report stated that an astounding 82% of people who suffered this type of fracture had been prescribed one of these bisphosphonate drugs. More research and investigation is being done to confirm that these drugs are causing this type of harm and whether or not they should remain on the market. Watch this video now to learn more. If you have additional questions about prescription drug laws, I want you to call me at (718) 469-6900. I welcome your call. Visit our website where you can view more videos and media content from our law firm. Parker Waichman LLP 300 Cadman Plaza West One Pierrepont Plaza, 12th Floor Brooklyn, NY 11201 (718) 469-6900 https://www.yourlawyer.com/brooklyn/
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Click here to own the entire video: http://www.lanisimpson.com/video/Medications How prolonged biphosphonate drugs (Fosamax, Actonel etc.) can decrease bone quality for some and increase hip and jaw fractures for others. Dr. Lani interviews Dr. Jennifer P. Schneider, MD, PhD. In March 2010, Dr. Schneider was featured on Diane Sawyer regarding the association of atypical low-impact fractures of the femur.
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http://www.yourlawyer.com/topics/overview/fosamax For those suffering from bone density problems, bisphosphonate medication such as Fosamax and Actonel is often prescribed as treatment. The drug is helped to prevent the breakage and weakening of a patient's bones. However, recent studies are beginning to show that overexposure to the drugs (such as patient's taking them regularly for years) has led to cause severe injuries to patients. Victims have been experiencing atypical femur fractures as a result of low energy accidents, such as simple slip and falls. An atypical femur fracture means that the fracture occurs in an unusual way, such as from low energy accidents. Women have reported these fractures occurring during basic daily activities like walking to the mailbox or getting out of their car. The femur bone, located in your thigh, is extremely strong. Along with that, the strongest area of the femur known as the subtrochanteric area can be affected by the drug. So not only do you have a strong bone, you have the strongest part of that bone at risk for fracture. It is usually only fractured by severe high energy events like car or skiing accidents or high falls. To suffer a break from such a small event as walking down the driveway is extremely rare and with exposure to drugs like Fosamax, these fractures can be very severe and come with no warning. Watch this video now to learn more. To learn more about prescription drugs, I encourage you to watch the video above and to explore our educational website at http://www.yourlawyer.com/topics/overview/fosamax. If you have legal questions, I want you to call me at (800) 800-9797. I welcome your call. Matthew McCauley Parker | Waichman LLP 6 Harbor Park Drive Port Washington, NY 11050 (800) 800-9797 http://yourlawyer.com
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http://www.yourlawyer.com/topics/overview/Bisphosphonates Osteopenia is a medical condition in which the density in a woman's bone increases the risks of breaks. Treatment of this condition includes bisphosphonate prescription drugs such as Fosamax, Actonel, and Boniva. Recent studies have shown that long-term exposure to these drugs is causing atypical fractures in women. What this means is under normal circumstances a fracture occurs due to a trauma such as a car or skiing accident. But women using drugs like Fosamax are suffering atypical fractures due to low energy acts, such as just walking around and climbing stairs. The real confusing part for any woman is why such a traumatic fracture occurred during normal activities. They question why they were injured when they weren't in a car accident or struck by anything. They constantly wonder why they were injured and what could possibly cause it. Only after seeing a physician does a patient understand that the prescription drug they've been using for years has harmed them. Studies are showing that women who have been using these medications for a period of more than 3 years are at an increased risk of femur fractures, without a traumatic event. Watch this video now to learn more. To learn more about prescription drugs, I encourage you to watch the video above and to explore our educational website at http://www.yourlawyer.com/topics/overview/Bisphosphonates. If you have legal questions, I want you to call me at (800) 800-9797. I welcome your call. Matthew McCauley Parker | Waichman LLP 6 Harbor Park Drive Port Washington, NY 11050 (800) 800-9797 http://yourlawyer.com
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To help patients understand the connection between non-steroidal anti-inflammatory drug use and the risks for potential stomach complications, Horizon Pharma, in collaboration with the American Gastroenterological Association created a 30-second broadcast educational piece. To learn more about this connection, visit: www.connecttoprotect.com Connect to Protect is a program developed by the AGA Institute with input from independent medical advisor, Dr. Byron Cryer from the University of Texas Southwestern Medical Center. Funding for the program is provided through an unrestricted grant by Horizon Pharma.
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http://preventosteoporosis-improveyourbones.com/why-should-you-not-use-the-drugs-prescribed-for-osteoporosis/ Although prescribed to 30 million Americans each year, the bisphosphonate patent medicines (the oral forms, including Fosamax®, Boniva®, Actonel®, and the latest additions to the bisphosphonate arsenal, the once yearly IV-administered patent medicines Reclast® and Aclasta®), are well known to be dangerous. The bisphosphonate patent medicines suppress the activity of osteoclasts, the body's specialized cells whose job it is to remove worn out, injured, or otherwise damaged bone. This is a task that must be taken care of before such weakened bone can be replaced with new strong bone. Moreover, the bisphosphonates don't just inhibit, they virtually crush all new bone formation. In the jaw, bisphosphonates' prevention of normal bone remodeling results in the accumulation of dying bone and its eventual exposure to the inside of the mouth, along with greatly increased risk of oral infection. A number of recent studies, including a meta-analysis of four studies involving more than 26,000 postmenopausal women, have now reported that bisphosphonates increase risk for "serious atrial fibrillation"—that is, an erratic, irregular heartbeat, by more than 150%. In other words, those at risk for serious side effects from bisphosphonates include not only women aged 60 and older who might need dental work, but also anyone with heart disease or diabetes—or more than one-third of the entire US adult population. Numerous other adverse effects have also been reported, including: ■erosions and ulcerations of the esophagus (throat); ■damage to the lining of the gastrointestinal tract; ■esophageal cancer; ■increased risk of stress fractures in bones; ■influenza-like illness; and ■myalgia (severe muscle pain) http://preventosteoporosis-improveyourbones.com/answers/osteoporosis/
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Fosamax is one of the leading prescription osteoporosis drugs. It contains alendronate, a compound that inhibits the breakdown of bones. However, Fosamax does nothing to build new bones. These effects on bone homeostasis can temporarily increase bone mineral density but eventually produce old, weak bones. Over the last 10 years, reports of adverse effects with Fosamax use have grown. One such side effect of Fosamax is the paradoxical increase in the risk of osteoporotic bone fractures in the thigh, hip, and femur. But is bone fracture really a paradoxical side effect of Fosamax? Read the complete article to find out why Fosamax is not only bad for your bones but also for your health. Learn more here... http://www.progressivehealth.com/natural-alternatives-to-fosamax-for-bone-health.htm Subscribe to Progressive Health here… https://www.youtube.com/channel/UCceE79hVWgorfCyyT7rEu1A Shop all of our HEALTH supplements here…https://goo.gl/1A6iie Pinterest: https://pinterest.com/progressivehealthcom Email: firstname.lastname@example.org
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Bisphosphonates long term are bone breakers not bone saviours http://www.betterbodychemistry.com/bones/bisphosphonates-bone-crew/ Bisphosphonates are the standard treatment for osteoporosis - initially they make a big difference, improving bone density but the benefit fades with time. Leave your questions or comments below ======================================= **Click below to SUBSCRIBE for More Videos http://www.youtube.com/subscription_center?add_user=spoonfulofscience ======================================= Dr Sandy Evans Scientist turned gremlin buster, helping your create BETTER BODY CHEMISTRY http://www.betterbodychemistry.com Facebook: http://www.facebook.com/betterbodychemistry/ Get the Free WILLPOWER REPORT http://upvir.al/5510/willpower-report
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Dr. Purchase, an orthopedic surgeon in San Francisco, CA, discusses the growing concern of atypical femur fractures in a subgroup of patients. Patients who have been on bisphosphonate medication, such as fosamax; boniva; actonel; and others, have been experiencing breaks or fractures in their legs. Dr. Purchase explains why this is happening, discusses the treatment, and answers some of the basic questions surrounding this developing problem.
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https://www.pro-activewellness.com There's a lot of "mis-information" out there regarding the "supposed" benefits of such drugs as Fosamax, Evista, Boniva, and Actonel. Many are unwittingly taking them unaware of the damage-some non-reversible- that's being done to them all the while thinking they're benefiting themselves and reversing their condition. This video clearly explains that nothing could be further from the truth Pro-Active Wellness & Injury Centre 1207 E Main Danville IL 61832 217-431-2010
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March 12, 2010 (New Orleans, Louisiana) — An unusual type of bone fracture has been reported in women who have taken bisphosphonates for osteopenia and osteoporosis for more than 4 years, according to 2 studies reported here at the American Association of Orthopaedic Surgeons 2010 Annual Meeting.. Bisphosphonates are wonderful drugs. They've cut the vertebral fracture rate by 70% and the hip fracture rate by 50%. People die from hip fractures. There has been great enthusiasm for these drugs, and clearly the rate of hip fractures is decreasing," said Joseph Lane, MD, chief of the Metabolic Bone Service at the Hospital for Special Surgery and professor of orthopedic surgery at Weill Cornell Medical College in New York CIty. But concern is mounting that long-term use might adversely affect bone quality, he added. There is significant morbidity and mortality associated with osteoporotic fractures. Vertebral fractures can result in chronic disabling pain, and 1 in 5 patients who have a hip fracture die within 1 year, researchers told meeting attendees. 03-10-2010] Patients and healthcare professionals may have questions about oral bisphosphonate medications and atypical subtrochanteric femur fractures fractures in the bone just below the hip joint. Oral bisphosphonates are commonly prescribed to prevent or treat osteoporosis in postmenopausal women. Common brand names of medications in this class include Fosamax®, Actonel®, Boniva®, and Reclast®.
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Fosamax is popularly known to help treat osteoporosis. But instead of improving the lives of thousands of its consumers, Fosamax have been causing serious bone fractures and injuries that led FDA and other authorities to invesitgate on this drug. Users of Fosamax (most are women) for five years are advised to speak to their doctor right away. People affected by Fosamax can seek advice from Hummer Law by visiting http:www.hummerlaw.com or call at 1-800-433-8420.
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#AnnalsITC #week2 Treatment for Fracture Prevention... Reducing risk for clinical fractures is the primary goal of treatment. Among postmenopausal women with os-teoporosis, treatment with alendronate, risedronate, zoledronic acid, or denosumab reduces risk for clinical fractures and new radiographic verte-bral fractures. Bisphosphonates lower risk for new radiographic vertebral fractures in osteoporotic men. Treatment with zoledronic acid decreases risk for clinical fractures among patients with recent hip fracture. Calcium and vitamin D supplementation at prudent doses should be recom-mended in older adults with inadequate dietary intake. Evidence does not support routine use of serial BMD or BTM measurements after initiation of drug treatment to monitor response or adherence with therapy. A treat-ment period of 5 years with oral bisphosphonates (3 years for intravenous bisphosphonates) is a reasonable strategy for many patients. Patients with osteoporosis should be counseled not to be fearful of receiving bisphos-phonates for 3–5 years, because the reduction in risk for disabling fractures outweighs the risk for short-term harms of treatment, and the potential risks for long-term harms of treatment are avoided with this approach.
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ACP has published an evidence-based clinical practice guideline http://bit.ly/2pUrLhu for treating low bone density or osteoporosis to prevent fractures in women and men. ACP’s treatment recommendations include generic bisphosphonates or denosumab and a recommendation against bone density monitoring during treatment.
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Fosamax, Actonel & Boniva - What You Need to Know - New York Attorney Matthew McCauley explains more at: https://www.yourlawyer.com/defective-drug-attorneys/ Watch as attorney Matthew McCauley of Parker Waichman discusses the increased health risks associated with bisphosphonate drugs and osteopinea. Osteopinea is a weakening of the bone and may develop into the more commonly known medical condition osteoporosis. To combat this condition, doctors have prescribed medications such as Fosamax and Actonel which include bisphosphonates. However, the FDA (Food and Drug Administration) has issued warnings considering these drugs and the possibility of a patient developing atypical femur fractures. What this means is the person will develop these fractures in their thigh bone during some type of low grade activity, like simply walking to the mailbox or climbing stairs. Watch this video now to learn more. If you have additional questions about defective drugs, I want you to call me at (212) 267-6700. I welcome your call. Visit our website where you can view more videos and media content from our law firm. Parker Waichman LLP 59 Maiden Lane 6th Floor New York, NY 10038 (212) 267-6700 https://www.yourlawyer.com/new-york/
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Please visit us http://defectivedrugsettlements.com/bone-density-drug-submission Patients have relied on this medication to help prevent osteoporosis, pagets disease and various other conditions for many years. Many doctors have turned to the bisphosphonates family of drugs to maintain bone strength in women,treat pagets disease and help in the aid to some cancer victims. But some users are experiencing serious side effects, including weak and brittle bones, loew energy femur fractures and something called dead jaw disease . If you have been affected , our attorneys are offering a free no-obligation consultation to discuss your legal options.
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Recent findings have suggested that patients on bisphosphonate therapy for prevention of osteoporosis are at increased risk of a rare, painful and debilitating type of leg fracture. Are you or a loved one at risk? What is the warning sign that a fracture is pending? Join Dr Robert Savage for this podcast to find out.
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The bisphosphonates are a well-known family of medications used to cure osteoporosis and atrial fibrillation. The following drugs are all in the bisphosphonate family: Fosamax, Actonel, Boniva, and Reclast. These medications are all very similar with some variations. Recently, these drugs have been reported to have caused severe health problems to its users. FDA is now undergoing thorough evaluation and investigation on these drugs. For more information, visit http:www.hummerlaw.com or you can also call at 1-800-433-8420.
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Information on bisphosphonates like fosamax and boniva, and what they are designed to do regarding bone health.
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Please Visit http://defectivedrugsettlements.com/bone-density-drug-submission It may seem strange to think that a drug designed to improve bone strength could cause death of the bone in the jaw, and bone fractures but that is exactly what is happening. Patients have relied on these medication to help prevent osteoporosis, pagets disease and various other conditions for many years. Many doctors have turned to the bisphosphonates family of drugs to maintain bone strength in women,treat pagets disease and help in the aid to some cancer victims. But a serious side effect common with this drug are bones that have become weak and brittle, and break . Another more serious side effect known as dead jaw disease. If you or a loved on has suffered, our attorneys are offering a free no obligation consultation to discuss your legal rights, compensation for your pain suffering and medical bills .
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Christina discusses the negative side effects she experiences from taking Boniva.
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There may be an increased risk of bone fractures of the thigh with bone strengthening bisphosphonates such as Boniva, Fosamax and Actonel that may be related to use for more than 5 years. Would you still take these drugs knowing the possible outcome? would love your comments at KarenLangston.com
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http://www.brandilaw.com Many people who were prescribed the drug Fosamax to treat osteoporosis have experienced an unusual fracture of the thighbone. The Brandi Law Firm represents a number of these patients. If you or loved one has used Fosamax and have had a fracture, contact us for a free consultation. San Francisco personal injury lawyers at The Brandi Law Firm have secured more than $1.8 billion in verdicts and settlements for our clients as a result of hard work, skilled negotiation, and aggressive litigation. Our 120 years of combined experience, coupled with our knowledge and record of success, give every client we represent complete confidence in our ability to protect his or her interests. Based in San Francisco, Brandi attorneys and staff represent clients throughout California, Arizona and Nevada, where our quality of work is second to none. Schedule your free consultation to speak with an experienced California personal injury lawyer now. We accept cases on a contingency fee basis, which means we do not charge our clients any fees until we recover financial compensation. Call us toll-free at 800-481-1615. Contact us today for experienced, compassionate advocacy.
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Dr Ramzi Matar discusses current medical management of patients taking bisphosphonate medications for treatment of malignant cancers, post menopausal women. How to avoid "BRONJ" or "Jaw Death." You can reach us at www.winterparkfamilydental.com
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T/I 10:35:10 NEW DRUG HOPE FOR WOMEN WITH OSTEOPOROSIS USA Natsot Duration: 1.01" Research into new drugs designed to treat osteoporosis, show a dramatic increase in bone mass among the women who take them. While current treatments with calcium and estrogen slow the disease process, these new drugs actually reverse it. Researchers have found that the bone density of patients prescribed Fosomax, Risedronate and slow release Sodium Fluoride increased by almost seven percent after three years. The bones of women who received no treatment, continued to grow thinner. The study also found that the drugs also decreased hip and spine fractures by almost 30 percent. The only side effect so far is mild heartburn. The studies ran for three years, but researchers say that after menopause women with a high risk of osteoporosis may have to take the drugs for the rest of their lives. All the drugs are experimental but the US Food and Drug Administration is expediting the approval process so they could be available as soon as next year. Victims of this disease say speed is important because osteoporosis causes 1.5 million fractures a year, and half of the people who have them never walk again. SHOWS: Woman getting x-rays. Dr Karpf, Researcher, SOT: "The fact that we've seen progressive bone mass increase in all the significant areas and progressive decrease in fractures including the most catastrophic non-spinal fractures. I think it is tremendously encouraging in this major health problem that is osteoporosis". Woman on bed in hospital, pan to x-ray of her spine. Doctor looking at x-rays. X-ray of curved spine. Doctor and patient going over x-rays. Patient. Woman receiving treatment. Dr Karpf saying that the loss of bone mass which is osteoporosis, takes years to develop and it is very likely that any therapy would need to be long term therapy. You can license this story through AP Archive: http://www.aparchive.com/metadata/youtube/ec9a92b8fc2c11920533618e9add3e45 Find out more about AP Archive: http://www.aparchive.com/HowWeWork
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Watch Michael Jackson, DDS as he explains and discusses the important links between Bisphosphonates and dentistry.
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http://www.rxwiki.com/fosamax https://www.youtube.com/playlist?list=PLXxn_pCvHVm4vIafvBCTOUNcX0w4tvCWK Fosamax, the brand-name form of alendronate, is a prescription medication used to treat osteoporosis and Paget's disease. It is also used to prevent osteoporosis in postmenopausal women. Fosamax is in a class of medications called bisphosphonates. These work by preventing bone breakdown and increasing bone density. Fosamax comes in tablet and liquid forms. It is usually taken daily or weekly, depending on the dose and form, on an empty stomach and with a full glass of water. Some common side effects are stomach pain, heartburn, and constipation.
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Fosamax, Actonel, Aredia, Zometa. Have you used them? The FDA links this class of drugs to the death of the jawbone. Only some patients are affected, so if youve been exposed, let your dental specialist know so they can watch out for osteonecrosis. Terrell Hogan is already seeking justice for victims of this terrible injury. If your jaw has been damaged, now is the time for action. Prescription drugs (bisphosphonates) linked to osteonecrosis of the jaw (Also known as "Dead Jaw", "BisPhossy Jaw" and "Jaw Necrosis"). Terrell Hogan is already prosecuting claims. Terrell Hogan is Jacksonville, Florida's largest personal injury trial law firm, experienced in over 25 practice areas including asbestos, mesothelioma, car accidents, trucking accidents, defective drugs, dog bites, Florida auto insurance, medical malpractice, wrongful death and unsafe products. We feel so strongly that everyone should have access to news about dangerous and defective products that we've included it on television as a service to the community. You may have seen or heard our alerts for the community about product recalls, and you can also find that information here on our website. Terrell Hogan believes that product recalls are worth repeating to help keep your family informed and safe.
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www.Fosamaxlawsuit.com 1-888 238-1998 Nation's Leading Legal Team for Bisphosphonates Jaw Osteonecrosis Cases Our Legal Team has been appointed to the Plaintiff Steering Committee for both the Zometa/Aredia and Fosamax Litigation This committee has the power to determine: -what legal theories to pursue, -what depositions will be taken and how to conduct discovery.
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Several lawsuits allege that Fosamax is a defective medication. They state that the drug can cause Osteonecrosis of the Jaw (ONJ). These suits claim that the drug's manufacturer, Merck & Co, marketed and sold Fosamax as a safe and effective medication to treat osteoporosis. They also claim that Merck did not adequately warn users of its side effects. Fleming & Associates, L.L.P.
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Peptic ulcers are open sores that develop on the inside lining of your stomach and the upper portion of your small intestine. The most common symptom of a peptic ulcer is stomach pain. Peptic ulcers include: Gastric ulcers that occur on the inside of the stomachDuodenal ulcers that occur on the inside of the upper portion of your small intestine (duodenum)The most common causes of peptic ulcers are infection with the bacterium Helicobacter pylori (H. pylori) and long-term use of aspirin and certain other painkillers, such as ibuprofen (Advil, Motrin, others) and naproxen sodium (Aleve, Anaprox, others). Stress and spicy foods do not cause peptic ulcers. However, they can make your symptoms worse. Symptoms Burning stomach painFeeling of fullness, bloating or belchingFatty food intoleranceHeartburnNausea The most common peptic ulcer symptom is burning stomach pain. Stomach acid makes the pain worse, as does having an empty stomach. The pain can often be relieved by eating certain foods that buffer stomach acid or by taking an acid-reducing medication, but then it may come back. The pain may be worse between meals and at night. Nearly three-quarters of people with peptic ulcers don't have symptoms. Less often, ulcers may cause severe signs or symptoms such as: Vomiting or vomiting blood — which may appear red or blackDark blood in stools, or stools that are black or tarryTrouble breathingFeeling faintNausea or vomitingUnexplained weight lossAppetite change.s. Causes Peptic ulcers occur when acid in the digestive tract eats away at the inner surface of the stomach or small intestine. The acid can create a painful open sore that may bleed. Your digestive tract is coated with a mucous layer that normally protects against acid. But if the amount of acid is increased or the amount of mucus is decreased, you could develop an ulcer. Common causes include: A bacterium. Helicobacter pylori bacteria commonly live in the mucous layer that covers and protects tissues that line the stomach and small intestine. Often, the H. pylori bacterium causes no problems, but it can cause inflammation of the stomach's inner layer, producing an ulcer. It's not clear how H. pylori infection spreads. It may be transmitted from person to person by close contact, such as kissing. People may also contract H. pylori through food and water. Regular use of certain pain relievers. Taking aspirin, as well as certain over-the-counter and prescription pain medications called nonsteroidal anti-inflammatory drugs (NSAIDs) can irritate or inflame the lining of your stomach and small intestine. These medications include ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve, Anaprox, others), but not acetaminophen (Tylenol). Peptic ulcers are more common in older adults who take these pain medications frequently or in people who take these medications for osteoarthritis. Other medications. Taking certain other medications along with NSAIDs, such as steroids, anticoagulants, low-dose aspirin, selective serotonin reuptake inhibitors (SSRIs), alendronate (Fosamax) and risedronate (Actonel), can greatly increase the chance of developing ulcers. Risk factors In addition to taking certain pain medications, including aspirin, you may have an increased risk of peptic ulcers if you: Smoke. Smoking may increase the risk of peptic ulcers in people who are infected with H. pylori.Drink alcohol. Alcohol can irritate and erode the mucous lining of your stomach, and it increases the amount of stomach acid that's produced.Have untreated stress.Eat spicy foods. Alone, these factors do not cause ulcers, but they can make them worse and more difficult to heal. Complications Left untreated, peptic ulcers can result in: Internal bleeding. Bleeding can occur as slow blood loss that leads to anemia or as severe blood loss that may require hospitalization or a blood transfusion. Severe blood loss may cause black or bloody vomit or black or bloody stools.Infection. Peptic ulcers can eat a hole through (perforate) the wall of your stomach or small intestine, putting you at risk of serious infection of your abdominal cavity (peritonitis).Obstruction. Peptic ulcers can lead to swelling, inflammation or scarring that may block passage of food through the digestive tract. A blockage may make you become full easily, vomit and lose weight. Prevention You may reduce your risk of peptic ulcer if you follow the same strategies recommended as home remedies to treat ulcers. It may also be helpful to: Protect yourself from infections. It's not clear just how H. pylori spreads, but there's some evidence that it could be transmitted from person to person or through food and water. You can take steps to protect yourself from infections, such as H. pylori, by frequently washing your hands with soap and water and by eating foods that have been cooked completely. THANK YOU.....
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http://www.rotlaw.com/fosamax/ The osteoporosis drug alendronate sodium (or alendronic acid)—sold under the brand names Fosamax or Fosamax+D—has caused some users to fracture their femurs or experience some other harmful bone-related side effects, according to researchers.
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Question? What are the risks associated with taking Fosamax? Answer: Fosamax is designed to treat osteoporosis by strengthening bones and preventing bone loss. However, studies have linked Fosamax and other bisphosphonate drugs to an increased risk of broken bones and fractures. The risk is highest in the femur, which is the strongest bone in the body. Fosamax has also been linked to an increased risk of osteonecrosis of the jaw, otherwise known as "dead jaw disease." The Food and Drug Administration issued a warning in 2010 about the risk of femur fracture associated with bisphosphonate drugs. Studies suggest that women who take these drugs for longer than 5 years are at the great risk of suffering fractures.
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