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Will Gene Therapy Cure Cancer?
Gene therapy, an alteration of genes within the body to fight or prevent disease, has sparked a revolution in cancer treatment. Cancer is the 2nd leading cause of death in the United States, and the two main ways we treat it - radiation and chemotherapy - have severe side effects. In this episode of Fw:Thinking, Jonathan Strickland walks us through the process of human gene therapy, reveals it's exciting potential, and questions the ethics of genetic modification and altering DNA. We have a question for you! If you were a gene hacker, what crazy genetic mutation would you give yourself? Leave us a comment with your answer! -------------------------------------------------------- Subscribe to Fw:Thinking: http://www.youtube.com/subscription_center?add_user=fwthinking For the audio podcast, blog and more, visit the Fw:Thinking website: http://www.fwthinking.com Fw:Thinking on Twitter: http://www.twitter.com/fwthinking Jonathan Stickland on Twitter: http://www.twitter.com/jonstrickland Fw:Thinking on Facebook: http://www.facebook.com/FWThinking01 Fw:Thinking on Google+: https://plus.google.com/u/0/108500616405453822675/ [TRANSCRIPT]: Feeling under the weather? Just tweak a chromosome and you'll be all better. Gene therapy. Now I'm not talking about support groups for people who can't fit into the same pants they wore in high school. I'm talking about the alteration of genes within the body to treat disease. Cancer is the second leading cause of death in the United States, and the two main ways we treat it are with radiation and chemotherapy. Both of which have severe side effects. Chemotherapy in particular can be devastating to healthy cells. So gene therapy has the promise of perhaps complimenting or maybe even replacing these other therapies. Currently there are a few different ways to use gene therapy to battle cancer. One way is just to remove the mutated genetic material and replace it with healthy material. Kind of like replacing a flat tire. Another way is to insert special genes into white blood cells. Now this gives those white blood cells the chance to detect and battle tumors. It's like giving a cancer cop a strong pot of coffee and a detailed sketch of what the bad cells look like. But the third, and this is my own personal favorite, is that cells happen to have a little self-destruct button inside them. Now this button gets pressed if there's too much mutation within that cell. But in cancer cells the button is deactivated. So with gene therapy you go in and reactivate that button. Press the button, no more cancer cell. But this raises a question. How do we actually get that genetic material into cells in the first place? Well, do you like spy movies? Because that's what we're talking about here - double agents! In this case, the double agent is a virus. Now normally a virus might be out there to kill you. But what scientists are doing is they're scooping the DNA out of viruses and putting a treatment gene into it, and then putting that into a patient's body. So, like a double agent, the virus works for our team now. In our spy movie, the viruses smuggle in the good genes, so when the cell replicates the good gene is copied instead of the mutated one. Take for example a cancer cell. Once inside the spy virus can deliver the gene that will halt its rampant replication. One such gene is called oligonucleotide. A single stranded piece of DNA that inserts itself directly in the slots of the mutated cell's double helix DNA, essentially jamming up the cell's replicating gears. The mutated segment of DNA can not be transcribed or copied once you've jammed up those gears. And in fact, scientists may one day be able to reverse this process, turning cancer cells back into healthy cells through cellular espionage. So far gene therapy has been used to treat very simple diseases and conditions where a gene is essentially flipped on or off and that effects everything else. Think of it like one of those strands of lights where one light is wrong and therefore the whole thing won't work. You know, kind of like these that I had back in college. Really you just have to find the one bulb that's wrong and fix it and it all comes on again! But some conditions are a little more complicated, and they actually involve lots of different combinations of genes that maybe switched on or off and so we have to determine what that combination is in order to use gene therapy to solve it. We're talking about over 20,000 proteins. This is a big problem. But as genetic information becomes easier for us to obtain, this raises some new questions. For example, should parents be able to determine what their child's eye color should be? Or height? Or sexual orientation? And if we're able to use gene therapy to cure or combat diseases and conditions, does that drastically alter our lifespan and in turn does that drastically alter world population?
Просмотров: 74392 Fw:Thinking
FDA Approves First Gene Therapy To Successfully Treat Cancer | NBC Nightly News
For the first time, the FDA Advisory Committee unanimously recommended approval for America’s first gene therapy treatment. » Subscribe to NBC News: http://nbcnews.to/SubscribeToNBC » Watch more NBC video: http://bit.ly/MoreNBCNews NBC News is a leading source of global news and information. Here you will find clips from NBC Nightly News, Meet The Press, and original digital videos. Subscribe to our channel for news stories, technology, politics, health, entertainment, science, business, and exclusive NBC investigations. Connect with NBC News Online! Visit NBCNews.Com: http://nbcnews.to/ReadNBC Find NBC News on Facebook: http://nbcnews.to/LikeNBC Follow NBC News on Twitter: http://nbcnews.to/FollowNBC Follow NBC News on Google+: http://nbcnews.to/PlusNBC Follow NBC News on Instagram: http://nbcnews.to/InstaNBC Follow NBC News on Pinterest: http://nbcnews.to/PinNBC FDA Approves First Gene Therapy To Successfully Treat Cancer | NBC Nightly News
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Destroying Cancer Using Your Own Genetically Modified Cells
Scientists are taking cancer patients' immune cells and engineering them to fight cancer. How does it work? This Genetically Modified Salmonella Destroys Brain Cancer - https://youtu.be/z94yUn33Ylo Sign Up For The Seeker Newsletter Here - http://bit.ly/1UO1PxI We got nominated for a People's Choice Webby! That means, you can help us win. Please, take a minute and vote for us here (thanks!): https://vote.webbyawards.com/PublicVoting#/2017/film-video/general-film/vr-cinematic-or-pre-rendered Read More: Gene Therapy Strategies to Correct or Eliminate Cancer Cells http://www.asgct.org/general-public/educational-resources/gene-therapy-and-cell-therapy-for-diseases/cancer-gene-and-cell-therapy "A number of gene therapy strategies are being evaluated in patients with cancer and these include manipulating cells to gain or lose function. For example, half of all cancers have a mutated p53 protein that interferes with the ability of tumor cells to self-destruct by a process called apoptosis." Cell Therapy Research http://www.gelifesciences.com/webapp/wcs/stores/servlet/catalog/en/GELifeSciences/applications/cell-therapy-research/ "In the past few decades, major progress in cell and molecular biology has enabled significant advances in science and medicine. Cell therapies are no longer generated simply by acquiring and processing cells or tissues." Immunotherapy: Using the Immune System to Treat Cancer https://www.cancer.gov/research/areas/treatment/immunotherapy-using-immune-system "In the past few years, the rapidly advancing field of cancer immunology has produced several new methods of treating cancer, called immunotherapies, that increase the strength of immune responses against tumors. Immunotherapies either stimulate the activities of specific components of the immune system or counteract signals produced by cancer cells that suppress immune responses." ____________________ Seeker inspires us to see the world through the lens of science and evokes a sense of curiosity, optimism and adventure. Watch More Seeker on our website http://www.seeker.com/shows/ Subscribe now! http://www.youtube.com/subscription_center?add_user=dnewschannel Seeker on Twitter http://twitter.com/seeker Trace Dominguez on Twitter https://twitter.com/tracedominguez Seeker on Facebook https://www.facebook.com/SeekerMedia/ Seeker on Google+ https://plus.google.com/u/0/+dnews Seeker http://www.seeker.com/ Sign Up For The Seeker Newsletter Here: http://bit.ly/1UO1PxI Written by: Trace Dominguez
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Genetically Engineered Cancer-Fighting Algae
Learn how scientists are fighting cancer... with algae! Hosted by: Michael Aranda ---------- Dooblydoo thanks go to the following Patreon supporters -- we couldn't make SciShow without them! Shout out to Justin Ove, David Campos, Chris Peters, Philippe von Bergen, Lilly Grainger, Happy Birthday!!, Fatima Iqbal, and Justin Lentz. ---------- Like SciShow? Want to help support us, and also get things to put on your walls, cover your torso and hold your liquids? Check out our awesome products over at DFTBA Records: http://dftba.com/scishow Or help support us by becoming our patron on Patreon: https://www.patreon.com/scishow ---------- Looking for SciShow elsewhere on the internet? Facebook: http://www.facebook.com/scishow Twitter: http://www.twitter.com/scishow Tumblr: http://scishow.tumblr.com Instagram: http://instagram.com/thescishow Sources: http://www.nature.com/ncomms/2015/151110/ncomms9791/full/ncomms9791.html http://www.ibtimes.co.uk/algae-genetically-engineered-kill-90-cancer-cells-without-harming-healthy-ones-1528038 http://www.livestrong.com/article/123423-chemotherapy-drugs-kill-cancer-cells/ http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0072611/ http://www.kinderkrebsinfo.de/patients/therapy/methods_of_treatment/pohkinderkrebsinfochemotherapie/cytostatic_agents/mode_of_action/index_eng.html http://www.oscarfish.com/article-home/water/82-diatoms.html http://book.bionumbers.org/how-quickly-do-different-cells-in-the-body-replace-themselves/
Просмотров: 238391 SciShow
Genetically Engineering Your DNA to Cure Disease | Retro Report and STAT
For the past 20 years, scientists have been trying to cure disease by altering our DNA. “Fixing the Code,” the second in our three-part series with STAT, examines how with CRISPR Cas-9 gene editing and the revival of gene therapy, they're closer than ever. To watch part one, "Finding the Code," https://youtu.be/gclpzqdV7hs.
Просмотров: 42908 RETRO REPORT
This Technology Could Help Cure Malaria, Cancer and HIV. But Will We Use It?
June 1 -- Clustered regularly interspaced short palindromic repeats, or Crispr, is a new genetic engineering tool that allows scientists to easily move around the genes of any living creature. In this episode of Sooner Than You Think, Bloomberg's Tom Randall shows us how this breakthrough genetic technology could help eliminate diseases, modify foods, and even create designer humans. (Video By Brandon Lisy, Tom Randall, Bran Dougherty-Johnson) Like this video? Subscribe to Bloomberg on YouTube: http://www.youtube.com/Bloomberg?sub_confirmation=1 And subscribe to Bloomberg Politics for the latest political news: http://www.youtube.com/BloombergPolitics?sub_confirmation=1 Bloomberg is the First Word in business news, delivering breaking news & analysis, up-to-the-minute market data, features, profiles and more: http://www.bloomberg.com Connect with us on... Twitter: https://twitter.com/business Facebook: https://www.facebook.com/bloombergbusiness Instagram: https://www.instagram.com/bloombergbusiness/ Bloomberg Television brings you coverage of the biggest business stories and exclusive interviews with newsmakers, 24 hours a day: http://www.bloomberg.com/live Connect with us on... Twitter: https://twitter.com/bloombergtv Facebook: https://www.facebook.com/BloombergTelevision Instagram: https://www.instagram.com/bloombergtv
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China Leads Race To Treat Cancer By Editing Genes With CRISPR
February 21st, 2018 Shaorong Deng gets an experimental treatment for cancer of the esophagus that uses his own immune system cells. They have been genetically modified with the gene-editing technique known as CRISPR. "China is starting to pull ahead of other parts of the world — maybe for the time — in regards to biomedicine," says Hallam Stevens, an anthropologist at the Nanyang Technological University in Singapore who studies Chinese bioscience. "They've been really investing heavily in it over the last couple of decades and it's starting to pay off in a big way." NPR
Просмотров: 6400 The Artificial Intelligence Channel
Can a New Gene Therapy Cure Cancer?
The FDA recently approved CAR-T therapy for treating certain types of cancer. Learn more by watching "NOVA Wonders: Can We Make Life?" at: http://www.pbs.org/wgbh/nova/wonders/#can-we-make-life PRODUCTION CREDITS Digital Producer Michael Rivera CAN WE MAKE LIFE? Produced, and Directed by Larry Klein © WGBH Educational Foundation 2018
Просмотров: 2417 NOVA PBS Official
Two New Groundbreaking Cancer Treatments
Finding safe, effective cancer treatments is tough, but in the last couple of weeks, we've taken two major steps toward a future where every type of cancer has a cure. Hosted by: Stefan Chin ---------- Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow ---------- Dooblydoo thanks go to the following Patreon supporters: D.A. Noe, Nicholas Smith, سلطان الخليفي, Piya Shedden, KatieMarie Magnone, Scott Satovsky Jr, Bella Nash, Charles Southerland, Patrick D. Ashmore, Tim Curwick, charles george, Kevin Bealer, Philippe von Bergen, Chris Peters, Fatima Iqbal ---------- Looking for SciShow elsewhere on the internet? Facebook: http://www.facebook.com/scishow Twitter: http://www.twitter.com/scishow Tumblr: http://scishow.tumblr.com Instagram: http://instagram.com/thescishow ---------- Sources: https://www.technologyreview.com/s/608771/the-fda-has-approved-the-first-gene-therapy-for-cancer/ https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm574058.htm https://www.technologyreview.com/s/603005/deaths-in-car-t-trials-haunt-promising-new-cancer-treatment/ https://www.scientificamerican.com/article/experts-gene-therapy/ http://www.philly.com/philly/business/philly-biotech-gets-fda-ok-to-review-gene-therapy-treatment-20170717.html https://www.cancer.gov/about-cancer/treatment/research/car-t-cells https://medicine.wustl.edu/news/zika-virus-kills-brain-cancer-stem-cells/ http://jem.rupress.org/content/early/2017/09/05/jem.20171093 http://www.who.int/mediacentre/factsheets/microcephaly/en/ http://www.who.int/emergencies/zika-virus/situation-report/7-april-2016/en/ http://www.nature.com/news/cancer-fighting-viruses-win-approval-1.18651 https://www.cdc.gov/zika/symptoms/symptoms.html Images: https://commons.wikimedia.org/wiki/File:Acute_leukemia-ALL.jpg https://commons.wikimedia.org/wiki/File:Leukemia-_SAG.jpg https://commons.wikimedia.org/wiki/File:CAR-Engineered_T-Cell_Adoptive_Transfer.jpg https://commons.wikimedia.org/wiki/File:Red_White_Blood_cells.jpg https://commons.wikimedia.org/wiki/File:Aedes_Aegypti_Mosquitoes_(25908400183).jpg https://commons.wikimedia.org/wiki/File:Microcephaly-comparison-500px.jpg https://commons.wikimedia.org/wiki/File:Zika_EM_CDC_20541.png https://commons.wikimedia.org/wiki/File:Zika.Virus.Rash.Arm.2014.jpg
Просмотров: 294834 SciShow
How CRISPR Can Help Fight Cancer
The New Yorker’s Michael Specter moderates a panel on the cutting-edge gene technology CRISPR with Jennifer Doudna, Kevin Esvelt, Feng Zhang, and Henry T. Greely. Still haven’t subscribed to The New Yorker on YouTube ►► http://bit.ly/newyorkeryoutubesub CONNECT WITH THE NEW YORKER Web: http://www.newyorker.com Twitter: http://twitter.com/NewYorker Facebook: http://www.facebook.com/newyorker Google+: http://plus.google.com/+newyorker Instagram: http://instagram.com/newyorkermag Pinterest: http://www.pinterest.com/thenewyorker Tumblr: http://newyorker.tumblr.com The Scene: http://thescene.com/thenewyorker Want even more? Subscribe to The Scene: http://bit.ly/subthescene How CRISPR Can Help Fight Cancer Producer: The New Yorker
Просмотров: 6665 The New Yorker
CRISPR gene editing will transform cancer treatment
Gene-editing technique CRISPR-cas works like a pair of scissors to cut DNA, inserting or reordering bits of genetic code with remarkable, science-fiction-like results. Subscribe: https://goo.gl/G5RXGs In humans, the technology is being tested to battle cancer — by removing patients’ immune cells, editing them, and reinserting the weaponized cells into the body to hunt cancer. One of the leading scientists who developed the technique is Jennifer Doudna, a biochemist at the University of California, Berkeley. Check out our full video catalog: https://goo.gl/lfcGfq Visit our playlists: https://goo.gl/94XbKx Like The Verge on Facebook: https://goo.gl/2P1aGc Follow on Twitter: https://goo.gl/XTWX61 Follow on Instagram: https://goo.gl/7ZeLvX Read More: http://www.theverge.com
Просмотров: 34702 The Verge
Gene Editing Cures Baby’s Leukemia, Could Solve Cancer in the Future
A new gene editing technique has been used by doctors at Great Ormond Street Hospital in London to successfully treat Layla Richards, a one-year-old diagnosed with leukemia, eliminating the diseased cells and leaving her cancer-free. This marks the first time ever the experimental form of gene therapy has saved a person’s life. What does this mean for the future of cancer treatment? We look at the medical breakthrough on the Lip News with Jo Ankier and Elliot Hill. https://www.newscientist.com/article/dn28454-gene-editing-saves-life-of-girl-dying-from-leukaemia http://www.cancer-research-awareness.com/why-chemotherapy-never-works.htmlin-world-first/ Newest Lip News playlist: https://www.youtube.com/watch?v=G4jWx9MGgNE&list=PLjk3H0GXhhGcjJDo6cQBCQprDMQyUQY3r&index=1 BUZZSAW interview clips - https://www.youtube.com/watch?v=bpVpdAzYM8Q&list=PLjk3H0GXhhGeWhHPas6M9sKUhThquDNOc&index=1 CRIME TIME clips playlist - https://www.youtube.com/watch?v=qnhI_zUHnvs&index=1&list=PLjk3H0GXhhGeC9DbpSnIvd2i9BHh2dBvv BYOD (Bring Your Own Doc) Highlight Videos- https://www.youtube.com/watch?v=z1LvJPQ2FBo&index=1&list=PLjk3H0GXhhGeu2DCf6Ouo7hTsA5QB2MAL MEDIA MAYHEM short videos playlist - https://www.youtube.com/watch?v=UALmeuYS29E&index=1&list=PLjk3H0GXhhGcz4un-zws5sMlCLk3NNjDP http://www.thelip.tv https://www.facebook.com/thelip.tv http://www.youtube.com/theliptv
Просмотров: 3484 TheLipTV
Curing Disease with Genetic Engineering
Leo Laporte and Jason Calacanis talk with Stanford scientist Dr. Lei Stanley Qi, who is using CRISPR and Cas9 to edit and modify DNA with the hope of curing diseases like cancer and diabetes.
Просмотров: 1106 TWiT Netcast Network
Viruses as Powerful Tools Cure Cancers and Genetic Diseases | Adam Schieferecke | TEDxMHK
Viruses are conventionally thought of as the bad guys: antagonists that can cause destruction in our bodies, sicknesses, birth defects, and even kill us. Adam suggests that they may also be beneficial, and possibly required for human survival. Adam is interested in the idea of using viruses as beneficial tools to help treat human genetic diseases such as cancer. He worked three academic years characterizing oncolytic (cancer-killing) poxviruses in the Division of Biology at Kansas State University. He completed a 2015 summer internship in the Department of Entomology at Kansas State University, which resulted in his co-authorship of a scientific manuscript published in the Journal of Experimental Biology. He studied measles virus replication as a 2016 Summer Undergraduate Research Fellow in the Virology and Gene Therapy Track at Mayo Clinic in Rochester, MN. He is a 2016 Barry Goldwater Scholar, which is the United States’ premier honor for college students in mathematics, natural science, and engineering fields. His additional interest in the intersection between science and public policy led to his nomination to represent Kansas State University in the 2017 Harry Truman Scholarship competition. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx
Просмотров: 2808 TEDx Talks
DIY Biohackers Are Editing Genes in Garages and Kitchens
With the latest breakthroughs in the life sciences, who needs a lab or degree? ---- Subscribe to our YouTube channel: http://youtube.com/reasontv Like us on Facebook: https://www.facebook.com/Reason.Magaz... Follow us on Twitter: https://twitter.com/reason Subscribe to our podcast at iTunes: https://goo.gl/az3a7a Reason is the planet's leading source of news, politics, and culture from a libertarian perspective. Go to reason.com for a point of view you won't get from legacy media and old left-right opinion magazines. ----- "A biohacker for me is somebody who is doing something clever or interesting in biology," says Josiah Zayner, a molecular biophysicist who runs The ODIN, a company that sells do-it-yourself genetic engineering kits. "They're usually these people that have been fucked by the system who are trying to unfuck themselves." Zayner is one of the leading figures in the biohacking movement and is the main organizer of the BioHack the Planet Conference, a yearly gathering of citizen scientists. This year, over 100 members of the biohacking community met in Oakland, California to discuss a wide array of issues from at-home genetic engineering to questions on bioethics. Biohackers have often been compared to computer hackers of the 1980s, but instead of breaking into and manipulating information technology systems, they're focused on hacking living organisms with the hopes of curing illnesses and in some cases obtaining superhuman powers. Their shared mission is to put this technology into the hands of as many people as possible. "People should be able to use all the technologies that science develops," says Zayner. "It shouldn't just be patented and given to companies or exclusively given to certain people." These do-it-yourself biologists say the democratization of science has given them the freedom to do work on projects that are often ignored by larger institutions. They're using gene editing technologies like CRISPR to create personalized treatments for those suffering from rare diseases or cancer, reverse engineering pharmaceuticals like Epi-Pens so people can make their own medicine at home, and even creating glow in the dark beer. "I think this is the most exciting time thus far in the history of the world to be alive with respect to what we can and will do with life forms," says Hank Greely, the director of the Center for Law and the Biosciences at Stanford University. But breakthroughs in the world of biohacking are drawing more scrutiny from federal regulators. Earlier this year, the Food and Drug Administration began placing restrictions on non-human genetic modifications and declared that genetically edited animals must be classified as drugs. This gives the agency broad authority over a number of do-it-yourself genetics tests and requires experiments involving animals to go through the same vetting process as a new drug. "I guess they couldn't call them cosmetics and they couldn't call them foods, so they're like dogs are drugs," states David Ishee, a Mississippi canine breeder who is working on editing out genetic diseases in dogs. "Everybody's worried about what someone could do with this technology and nobody seems to care about the damage that not doing it will cause because these animals are dying." Increasing regulation could undermine biohacking breakthroughs for humans as well. "I'm a huge fan of deregulation because I believe in the inherent goodness of capitalism," says Zayner. "Stuff doesn't progress unless people do useful things with it." Produced by Alexis Garcia and Justin Monticello. Camera by Garcia, Monticello, and Zach Weissmueller. Ascent by Jon Luc Hefferman is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) Source: http://freemusicarchive.org/music/Jon_Luc_Hefferman/Production_Music_1841/Ascent Artist: http://freemusicarchive.org/music/Jon_Luc_Hefferman/ Cut and Run - Electronic Hard by Kevin MacLeod is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) Source: http://incompetech.com/music/royalty-free/index.html?isrc=USUAN1100851 Artist: http://incompetech.com/ New Dawn by Bensound is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) Source: https://www.bensound.com/royalty-free-music/cinematic/2 Artist: https://www.bensound.com/ Sci-Fi by Bensound is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) Source: https://www.bensound.com/royalty-free-music/electronica Artist: https://www.bensound.com/ Wake Up by Kai Engel is licensed under a Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) Source: http://freemusicarchive.org/music/Kai_Engel/The_Scope/Kai_Engel_-_The_Scope_-_06_Wake_Up Artist: http://freemusicarchive.org/music/Kai_Engel/
Просмотров: 43363 ReasonTV
Cancer breakthrough? Genetic sequencing could change treatment
Researchers at 14 major American cancer centers teamed up to identify switches that fuel cancer, using genetic sequencing. Dr. David Agus, of the Westside Cancer Center at the University of Southern California, talks to the "CBS This Morning" co-hosts about the possible beginning of the end for chemotherapy as the standard of care.
Просмотров: 530 CBS This Morning
Iran Anti Cancer enzyme L-asparaginase II, National Institute of Genetic Engineering & Biotechnology
November 1, 2018 (Persian calendar 1397/8/10) Iran National Institute of Genetic Engineering & Biotechnology (NIGEB پژوهشگاه ملي مهندسي ژنتيك و زيست فناوري ايران) official website http://www.nigeb.ac.ir Research and Education at National Institute of Genetic Engineering & Biotechnology (NIGEB) The National Institute for Genetic Engineering and Biotechnology (NIGEB) was established in 1989 under the supervision of the Ministry of Science, Research and Technology. Since then, NIGEB has been given a mandate to undertake original, state-of-the-art research activities. It was established with dual purposes of promoting research in avant-garde areas of biological sciences and biotechnology as well as providing advanced training and educational programs for scientists and students from other universities and academic institutions. The activities of NIGEB are being conducted by three sub-institutes heading nine departments. Institute of Agricultural Biotechnology (IAB) runs the departments of Plant Bioproducts, Plant Molecular Biotechnology, and Animal Biotechnology, the Institute of Industrial and Environmental Biotechnology (IIEB) manages the departments of Bioprocess Engineering, Systems Biotechnology as well as Energy and Environmental Biotechnology. And the Institute of Medical Biotechnology (IMB) conducts the departments of Medical Genetics, Stem Cell, and Molecular Medicine. Each institute or department is dedicated to a highly innovative and pioneering investigation in the different fields of biotechnology. NIGEB is located in Tehran in a unique complex of buildings designed and equipped for studies on various biotechnology fields. The town of Chitgar چيتگر, about 17 km northwest of Tehran, houses the institute’s new main campus with numerous laboratories and facilities as well as a modern pilot plant for exploring the production of new Biotherapeutics. Researchers of universities and research centers from inside the country and around the globe are cooperating with NIGEB through shared research projects and applied educational courses. The time preceding the foundation of this institute coincides with the impetuous growth of the biotechnology and extensive spreading of the concepts and methods of genetic engineering in Iran. At the turning point in terms of globalization, biotechnology acts as a phase of evolution. Accordingly, research at NIGEB is linked directly to the science development. However, a balance between technical advancement and harmony with humanity and environment is of utmost importance. In other words, the coupling of scientific technology with ethics and morality is necessary; thus, we at NIGEB are sincere in our acknowledgement toward it. Furthermore, education and research generally have been carried out individually by our universities so far, but we must acknowledge that presently, we live in an interactive world society. Looking squarely at current needs and realities, NIGEB is determined to contribute to the well-being of the country community by working to transmit the intellectual wisdom of human society, helping to create a safe global environment, and contributing knowledge and expertise that will be of use to future generations. Research in advanced areas of science and technology must be built on a foundation of unique ideas, and it is only when such ideas lead to innovations and discoveries of exemplary ingenuity that research can be said to yield truly fruitful results. The purpose of this home page is publicizing NIGEB research and educational goals. We hope that it will deepen people understanding of these aims and open up new possibilities for future academic collaborations. NIGEB has now the potential to become an internationally recognized academic center with a high reputation. The faculty, staff and students of NIGEB are making continuous efforts for developing, striving for renovation and perfection and although still faced with numerous problems, never ceases in its search. Objectives of NIGEB § Do mission-oriented scientific research in related fields of genetic engineering and biotechnology § Improve researches and laying proper foundation for promotion of research activities § Establish appropriate approaches for converting the research results into technology and upgrading the scale of productions to semi-industrial level § Marketing and commercialization of produced technologies § Provide the country required packages of technical knowledge in biotechnology areas § Collaboration for training researchers in various areas of biotechnology with regard to the priorities setting in the country’s socio-economic program Iran Anti Cancer enzyme L-asparaginase II project, National Institute of Genetic Engineering & Biotechnology پروژه آنزيم ضد سرطان پژوهشگاه مهندسي ژنتيك و زيست فناوري ايران
Просмотров: 393 Persian_boy
How Does Gene Therapy Work?
Scientists have promised that gene therapy will be the next big leap for medicine. It's a term that's tossed about regularly, but what is it exactly? Trace shows us how scientists can change your very genetic code. Read More: How does gene therapy work? http://ghr.nlm.nih.gov/handbook/therapy/procedures "Gene therapy is designed to introduce genetic material into cells to compensate for abnormal genes or to make a beneficial protein. If a mutated gene causes a necessary protein to be faulty or missing, gene therapy may be able to introduce a normal copy of the gene to restore the function of the protein." Gene therapy trial 'cures children' http://www.bbc.co.uk/news/health-23269778 "A disease which robs children of the ability to walk and talk has been cured by pioneering gene therapy to correct errors in their DNA, say doctors." Gene therapy cures diabetic dogs http://www.newscientist.com/article/dn23163-gene-therapy-cures-diabetic-dogs.html "Five diabetic beagles no longer needed insulin injections after being given two extra genes, with two of them still alive more than four years later." Gene Therapy for Cancer: Questions and Answers http://www.cancer.gov/cancertopics/factsheet/Therapy/gene "Gene therapy is an experimental treatment that involves introducing genetic material into a person's cells to fight or prevent disease." How does gene therapy work? http://www.scientificamerican.com/article.cfm?id=experts-gene-therapy "Gene therapy is the addition of new genes to a patient's cells to replace missing or malfunctioning genes. Researchers typically do this using a virus to carry the genetic cargo into cells, because that's what viruses evolved to do with their own genetic material." Gene therapy cures leukaemia in eight days http://www.newscientist.com/article/mg21729104.100-gene-therapy-cures-leukaemia-in- eight-days.html WITHIN just eight days of starting a novel gene therapy, David Aponte's "incurable" leukaemia had vanished. For four other patients, the same happened within eight weeks, although one later died from a blood clot unrelated to the treatment, and another after relapsing. Cell Therapy Shows Promise for Acute Type of Leukemia http://www.nytimes.com/2013/03/21/health/altered-t-cell-therapy-shows-promise-for-acute-leukemia.html?pagewanted=all&_r=0 "A treatment that genetically alters a patient's own immune cells to fight cancer has, for the first time, produced remissions in adults with an acute leukemia that is usually lethal, researchers are reporting." Watch More: Tricking the Immune System http://www.youtube.com/watch?v=Kr_HRlGuGB8 Babies with 3 Parents?! http://www.youtube.com/watch?v=jQxsW_H5qr4 Pick Your Poison: Cyanide http://www.youtube.com/watch?v=JDBrdEF5UcE&feature=c4-overview-vl&list=PLy_MdHDhCQ6mljhWJq8k0oam2nrQBojWY ____________________ DNews is dedicated to satisfying your curiosity and to bringing you mind-bending stories & perspectives you won't find anywhere else! New videos twice daily. Watch More DNews on TestTube http://testtube.com/dnews Subscribe now! http://www.youtube.com/subscription_center?add_user=dnewschannel DNews on Twitter http://twitter.com/dnews Anthony Carboni on Twitter http://twitter.com/acarboni Laci Green on Twitter http://twitter.com/gogreen18 Trace Dominguez on Twitter http://twitter.com/trace501 DNews on Facebook http://facebook.com/dnews DNews on Google+ http://gplus.to/dnews Discovery News http://discoverynews.com
Просмотров: 167817 Seeker
My career in genomics: cancer biology
For more information about this film, as well as links to other related content, please view our page on yourgenome: http://www.yourgenome.org/video/my-career-in-genomics-cancer-biology In this film Niki Patel talks about her research at the Wellcome Trust Sanger Institute looking at the genetics of cancer. This is one of a series of films providing a unique insight into different careers in the field of genomics.
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FDA approves breakthrough CAR-T therapy for leukemia
With FDA approval, breakthrough CAR-T therapy for cancer becomes the first approved gene therapy treatment in the U.S. It reprograms the body's own immune system to attack a deadly type of blood cancer and has been effective in treating children and young adults with leukemia. Cancer expert Dr. David Agus joins "CBS This Morning" to discuss who's eligible and the risks of treatment. Subscribe to the "CBS This Morning" Channel HERE: http://bit.ly/1Q0v2hE Watch "CBS This Morning" HERE: http://bit.ly/1T88yAR Watch the latest installment of "Note to Self," only on "CBS This Morning," HERE: http://cbsn.ws/1Sh8XlB Follow "CBS This Morning" on Instagram HERE: http://bit.ly/1Q7NGnY Like "CBS This Morning" on Facebook HERE: http://on.fb.me/1LhtdvI Follow "CBS This Morning" on Twitter HERE: http://bit.ly/1Xj5W3p Follow "CBS This Morning" on Google+ HERE: http://bit.ly/1SIM4I8 Get the latest news and best in original reporting from CBS News delivered to your inbox. Subscribe to newsletters HERE: http://cbsn.ws/1RqHw7T Get your news on the go! Download CBS News mobile apps HERE: http://cbsn.ws/1Xb1WC8 Get new episodes of shows you love across devices the next day, stream local news live, and watch full seasons of CBS fan favorites anytime, anywhere with CBS All Access. Try it free! http://bit.ly/1OQA29B --- Delivered by Charlie Rose, Norah O’Donnell and Gayle King, "CBS This Morning" offers a thoughtful, substantive and insightful source of news and information to a daily audience of 3 million viewers. The Emmy Award-winning broadcast presents a mix of daily news, coverage of developing stories of national and global significance, and interviews with leading figures in politics, business and entertainment. Check local listings for "CBS This Morning" broadcast times.
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The Future of Cancer Research | Freethink
Intel employee Bryce Olson was diagnosed with stage 4 prostate cancer. When the standard of care didn’t work, Bryce turned to genomic sequencing which allowed his doctors to identify specific genetic drivers of his disease and identify specific treatments and clinical trials that were a fit for his specific cancer. This precision medicine approach helped send his cancer into remission for several years. Now that his cancer has returned, Bryce is working with the Broad Institute and other leaders in the field of advanced cancer research to use artificial intelligence powered by Intel technology to discover new, innovative solutions that can help him and millions of others like him around the world. Learn more about the work Intel is doing to power the future of healthcare intelligence at intel.com/healthcare For more stories profiling pioneers of science and tech innovation, subscribe to Freethink at https://www.youtube.com/freethinkmedia And follow Freethink across other platforms here: Facebook: https://www.facebook.com/freethinkmedia Twitter: https://twitter.com/freethinkmedia Instagram: https://www.instagram.com/freethinkmedia Website: http://www.freethink.com
Просмотров: 2767800 Freethink
Genetic Engineering Will Change Everything Forever – CRISPR
Designer babies, the end of diseases, genetically modified humans that never age. Outrageous things that used to be science fiction are suddenly becoming reality. The only thing we know for sure is that things will change irreversibly. Support us on Patreon so we can make more videos (and get cool stuff in return): https://www.patreon.com/Kurzgesagt?ty=h Kurzgesagt merch here: http://bit.ly/1P1hQIH Get the music of the video here: soundcloud: http://bit.ly/2aRxNZd bandcamp: http://bit.ly/2berrSW http://www.epic-mountain.com Thanks to Volker Henn, James Gurney and (prefers anonymity) for help with this video! THANKS A LOT TO OUR LOVELY PATRONS FOR SUPPORTING US: Jeffrey Schneider, Konstantin Kaganovich, Tom Leiser, Archie Castillo, Russell Eishard, Ben Kershaw, Marius Stollen, Henry Bowman, Ben Johns, Bogdan Radu, Sam Toland, Pierre Thalamy, Christopher Morgan, Rocks Arent People, Ross Devereux, Pascal Michaud, Derek DuBreuil, Sofia Quintero, Robert Swiniarski, Merkt Kızılırmak, Michelle Rowley, Andy Dong, Saphir Patel, Harris Rotto, Thomas Huzij, Ryan James Burke, NTRX, Chaz Lewis, Amir Resali, The War on Stupid, John Pestana, Lucien Delbert, iaDRM, Jacob Edwards, Lauritz Klaus, Jason Hunt, Marcus : ), Taylor Lau, Rhett H Eisenberg, Mr.Z, Jeremy Dumet, Fatman13, Kasturi Raghavan, Kousora, Rich Sekmistrz, Mozart Peter, Gaby Germanos, Andreas Hertle, Alena Vlachova, Zdravko Šašek SOURCES AND FURTHER READING: The best book we read about the topic: GMO Sapiens https://goo.gl/NxFmk8 (affiliate link, we get a cut if buy the book!) – Good Overview by Wired: http://bit.ly/1DuM4zq –timeline of computer development: http://bit.ly/1VtiJ0N – Selective breeding: http://bit.ly/29GaPVS – DNA: http://bit.ly/1rQs8Yk – Radiation research: http://bit.ly/2ad6wT1 – inserting DNA snippets into organisms: http://bit.ly/2apyqbj – First genetically modified animal: http://bit.ly/2abkfYO – First GM patent: http://bit.ly/2a5cCox – chemicals produced by GMOs: http://bit.ly/29UvTbh http://bit.ly/2abeHwU http://bit.ly/2a86sBy – Flavr Savr Tomato: http://bit.ly/29YPVwN – First Human Engineering: http://bit.ly/29ZTfsf – glowing fish: http://bit.ly/29UwuJU – CRISPR: http://go.nature.com/24Nhykm – HIV cut from cells and rats with CRISPR: http://go.nature.com/1RwR1xI http://ti.me/1TlADSi – first human CRISPR trials fighting cancer: http://go.nature.com/28PW40r first human CRISPR trial approved by Chinese for August 2016: http://go.nature.com/29RYNnK – genetic diseases: http://go.nature.com/2a8f7ny – pregnancies with Down Syndrome terminated: http://bit.ly/2acVyvg ( 1999 European study) – CRISPR and aging: http://bit.ly/2a3NYAV http://bit.ly/SuomTy http://go.nature.com/29WpDj1 http://ti.me/1R7Vus9 Help us caption & translate this video! http://www.youtube.com/timedtext_cs_panel?c=UCsXVk37bltHxD1rDPwtNM8Q&tab=2
Просмотров: 10238635 Kurzgesagt – In a Nutshell
Genetically Engineered Immune Cells Treat Cancer
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Просмотров: 27 4Wow
How to Cure Aging – During Your Lifetime?
What if we could stop aging forever? Thanks so much for help with the video to Lifespan.io. Check them out and learn how you can get active here: Lifespan.io facebook.com/LifespanIO https://www.leafscience.org/blog/ Kurzgesagt Newsletter: http://eepurl.com/cRUQxz Support us on Patreon so we can make more videos (and get cool stuff in return): https://www.patreon.com/Kurzgesagt?ty=h Kurzgesagt merch: http://bit.ly/1P1hQIH The MUSIC of the video: Soundcloud: http://bit.ly/2gZBGNB Bandcamp: http://bit.ly/2lKjJYF Facebook: http://bit.ly/2qW6bY4 THANKS A LOT TO OUR LOVELY PATRONS FOR SUPPORTING US: Phil Winterleitner, David Blayney, Stuart Dunlop, Jordi Riera, James Lamberg, Alexander Fortin, Philipp Hiestand, Shalyn Thong, Elizabeth Meisterling, Tyler Graybill, Felix Diercks, Carson Hynes, Julian Maurel, Jacek Złydach, Paul Lenoue, Stephen Murillo, Justin Fowler, Michael Andregg, Justin Stocking, Andrew, Michael Altarriba, Andy Holaday, Karel Hulec, CJ Canton, Cédric Coulombe, Radomir Kaleta, J K, Rada199, Claudio Fan, etti, Zen, Alen Kecic, Patrick Preuss, deMat01, Erickson Phoenix, iamBadgers, Tom Motto, William Asheshov, Chris O'Hara, Lobo Olsson, Zachary Hall, Donis A., Ismael, The_CJ, Michal Janček, Lars Midgaard, ElRichMC, Mariann Nagy Help us caption & translate this video! http://www.youtube.com/timedtext_cs_panel?c=UCsXVk37bltHxD1rDPwtNM8Q&tab=2 How to Cure Aging – During Your Lifetime?
Просмотров: 4026602 Kurzgesagt – In a Nutshell
T-cells: army of cancer killing clones | André Choulika | TEDxSaclay
Fight cancer, but how? Chemotherapy kills cancer cells but also healthy cells. The use of our immune cells (T-cells) could allow a more targeted attack of cancer cells but are limited. Genetic engineering makes it possible to transform our T-cells into an army of super-killer cells (CAR-T) which reinjected can destroy a tumor. Clinical trials have shown that, but this is just the beginning of a new era where reprogrammed cells can become super sophisticated drugs. A medical revolution begins! André Choulika, Ph.D., is one of the founders of Cellectis and served as Chief Executive Officer since the company's inception in 1999. He is Chairman of the Board of Directors since 2011 and President of Calyxt since August 2010. From 1997 to 1999, Dr. Choulika worked as a post-doctoral fellow in the Division of Molecular Medicine at Boston Children’s Hospital, where he was one of the inventors of nuclease-based genome editing technologies and a pioneer in the analysis and use of meganucleases to modify complex genomes. After receiving his Ph.D. in molecular virology from the University of Paris VI (Pierre et Marie Curie), he completed a research fellowship in the Harvard Medical School Department of Genetics. His management training is from the HEC (Challenge +). This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at https://www.ted.com/tedx
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CRISPR Gene-Editing tested in a Person for the First time to cure Cancer in China | QPT
A Chinese group has become the first to inject a person with cells that contain genes edited using the revolutionary CRISPR–Cas9 technique. It could trigger a biomedical race between China and the US. On 28 October, a team in China delivered the modified cells into a patient with aggressive lung cancer as part of a clinical trial at the West China Hospital. Earlier clinical trials using cells edited with a different technique have excited clinicians. The introduction of CRISPR, which is simpler and more efficient than other techniques, will probably accelerate the race to get gene-edited cells into the clinic across the world. News Source: CRISPR gene-editing tested in a person for the first time http://www.nature.com/news/crispr-gene-editing-tested-in-a-person-for-the-first-time-1.20988 Image Courtesy: Steve Gschmeissner/Science Photo Library Video Courtesy: UC Berkeley Related Videos: Using Light to control CRISPR Genome Editing https://www.youtube.com/watch?v=hG1WYp5W9d4 MIT Engineers program Human Cells to store complex Histories in their DNA https://www.youtube.com/watch?v=hD2cFQmEmNI CRISPR: Gene Editing Will Change Everything Forever. Is this Genetic Engineering growth Good or Bad? https://www.youtube.com/watch?v=sp9eCYHcP5I Curing disease by repairing faulty Genes. MIT boosts efficiency of CRISPR genome-editing system. https://www.youtube.com/watch?v=bdnaaJchMnI Gene Editing Tool "CRISPR Cas9" paves way for Sickle Cell Cure https://www.youtube.com/watch?v=saJ4Be8YiZU Global CRISPR/Cas9 Market will Cross US$ 1.5 Billion by 2022 https://www.youtube.com/watch?v=_4f6O7AETQw
Просмотров: 2000 Rajamanickam Antonimuthu
Cancer Immunotherapy using Genetic Engineering: 21st Century Medicine - Prof. Emma Morris
Professor Emma Morris speaks about genetically engineering retroviruses that make the body immune to cancer. Authentic Biology Symposium 2016
Просмотров: 213 The Institute for Research in Schools
Are GMOs Good or Bad? Genetic Engineering & Our Food
Are GMOs bad for your health? Or is this fear unfounded? Support us on Patreon so we can make more videos (and get cool stuff in return): https://www.patreon.com/Kurzgesagt?ty=h Kurzgesagt merch here: http://bit.ly/1P1hQIH Get the music of the video here: Soundcloud: http://bit.ly/2okalIy Bandcamp: http://bit.ly/2nCOQnR Facebook: https://www.facebook.com/epic-mountain-music THANKS A LOT TO OUR LOVELY PATRONS FOR SUPPORTING US: Richard Martinez, Festive Madman, Christopher Jimenez, William Robertson, Peter, Christin Paul, Sitong Li, Noah T Blanchard, conquesttintin, Lukas Schopphoff, Vivian Wagner, Leon Klang, Max Wahrhaftig, Adrià, Vila Ruaix, Christian Fiedler, Adam Martin, Benjamin Bethea, Robert Smith, Stif, Alexandria Walters, Jack Neubauer, Gabriele Simeone, ComradKing, Michael Malocha, Paul Rozs, Mark Provan, oskars, Dar, Daria Blednova, Joshua Smith, Ke2theKe, Constantin-Marius Jaeck, Christopher Davidson, DK DK, Jon, Richter, Nova Kane, Someone, David Joseph, nsa smith, Husita, Robert Arnaud, SG2 Infinity, Jawnan, Dan Lukas Lundh, Jose Retana, Jake wirtanen, Abdulaziz Al-Kuwari, Roy Malamud, Krishna Yogi, Gonçalo Marques, Duke spork, itamar steigrad, I3aneFuL, Georg Kranz, Shiro Kawa, Janet Kim, Santina Lin, Chris Serdaris, Occam, Radek Starý, Abraham Callahan, Brent Charles, Emil Kampp, Scott Chamberlin-Wibbeke, Sebastian Gemal Vitting, Ray Jobbins, Jacques Quail, Scott Yanos, Tim Preuß, Attila Bögözi, Tarot, Noah Fechter-Dickson, Bogdan Bucur, James Bell, Jarek, Noah T-Blanchard, Adriana Vila SOURCES: #What is natural: GM insulin: http://bit.ly/2ncHaW5 Genetic engineering for thousands of years: http://bit.ly/2eCHKfi http://bit.ly/2mLCvPm CRISPR: http://bit.ly/2ncI2uN # Are GMOs bad for your health GMOs and gene flow: http://bit.ly/2bKauBe terminator seeds: http://n.pr/2o0ADSZ http://bit.ly/2obZ9NS Plants that are destined to be eaten are evaluated by different agencies http://bit.ly/2mLbU5g http://bit.ly/2nGPtNy http://bit.ly/2ncMXf0 GMOs are safe– various studies and reports by respected authorities: National Academies of Science, Engineering and Medicine: http://bit.ly/2o0IT55 An overview of the last 10 years of genetically engineered crop safety research: http://bit.ly/2ot8tfH Letter of 110 Nobel laureates vouching for GMOs: http://bit.ly/295Nvg1 WHO: http://bit.ly/1slbfSV Various others: http://bit.ly/1pEOq9T http://bit.ly/1xq9iGn http://bit.ly/14XU8yl http://pewrsr.ch/1LqMLAe http://bit.ly/2nduCOV http://bit.ly/20BHOsU Bt crops: http://bit.ly/2nd9rg8 herbicide-resistant crops: http://bit.ly/2o5kdJk http://bit.ly/2o5nSGQ # What good GMOs can do Bt eggplants: http://bit.ly/2nHbdsW http://bit.ly/2nvmg89 Gm papaya: http://bit.ly/2nbN0ab http://bit.ly/2nvl6cz http://bit.ly/2ndxPy0 # Look in the crystal ball: drought-resistant crops: http://bit.ly/2mLmnxf plants that produce more nutrients: http://bbc.in/1WxsfnJ vitamin-fortified banana: http://bit.ly/1MKS0sJ nitrogen-fixing crops: http://bit.ly/2mLN9Wn http://bit.ly/2nc9mrZ Chestnut tree: http://bit.ly/1VqkL2D Potential for landsparing: http://go.nature.com/2oc18Sp http://bit.ly/1T1J2NX # Further reading: Bt cotton in India: http://bit.ly/2nH5AdZ http://bit.ly/1JQKG1u Article on popular science: http://bit.ly/2o5oVqp Blog series on GMOs: http://bit.ly/2o18w5X Ecomodernist manifesto: http://bit.ly/1PSVE6n Help us caption & translate this video! http://www.youtube.com/timedtext_cs_panel?c=UCsXVk37bltHxD1rDPwtNM8Q&tab=2 Are GMOs Good or Bad? Genetic Engineering & Our Food
Просмотров: 5812322 Kurzgesagt – In a Nutshell
Taking genetic engineering & therapy to the next level
Clustered Regularly Interspaced Short Palindromic (CRISPR) is a family of DNA sequences in bacteria. The recognition of these sequences form the basis of genome editing technology, this allows scientists to make permanent modification to genes within organisms. This is one of the most promising strategies for genetic engineering and gene therapy. Visit Chemical Science, the flagship journal of the Royal Society of Chemistry for more articles and breakthroughs. http://rsc.li/chemical-science
Просмотров: 1444 Royal Society Of Chemistry
Humanity towards immortality, The gene-editing technology on humans Chinese scientists have become the first in the world to inject an adult human with cells that have been genetically edited using the revolutionary CRISPR/Cas9 technique. The CRISPR-edited cells were injected on October 28 by a team from the Sichuan University in Chengdu, as part of a clinical trial against aggressive lung cancer - and experts think it could trigger a biomedical race between the US and China. If you haven't heard of CRISPR as yet, Here are some insights Genome editing, or genome editing with engineered nucleases (GEEN) is a type of genetic engineering in which DNA is inserted, deleted or replaced in the genome of a living organism using engineered nucleases, or "molecular scissors." These nucleases create site-specific double-strand breaks (DSBs) at desired locations in the genome. The induced double-strand breaks are repaired through nonhomologous end-joining (NHEJ) or homologous recombination (HR), resulting in targeted mutations, There are currently four families of engineered nucleases being used: meganucleases, zinc finger nucleases (ZFNs), transcription activator-like effector-based nucleases (TALEN), and the CRISPR-Cas system, The CRISPR-Cas system was selected by Science as 2015 Breakthrough of the Year. The new gene-editing technique is poised to revolutionize the way we treat disease, by offering scientists a quick and easy way to cut and paste genes from our DNA. The CRISPR-Cas9 system consists of two key molecules that introduce a change (mutation) into the DNA. These are , an enzyme called Cas9. This acts as a pair of ‘molecular scissors’ that can cut the two strands of DNA at a specific location in the genome so that bits of DNA can then be added or removed and a piece of RNA called guide RNA (gRNA). This consists of a small piece of pre-designed RNA sequence (about 20 bases long) located within a longer RNA scaffold. The scaffold part binds to DNA and the pre-designed sequence ‘guides’ Cas9 to the right part of the genome. This makes sure that the Cas9 enzyme cuts at the right point in the genome. The guide RNA is designed to find and bind to a specific sequence in the DNA. The guide RNA has RNA bases that are complementary to those of the target DNA sequence in the genome. This means that, at least in theory, the guide RNA will only bind to the target sequence and no other regions of the genome. The Cas9 follows the guide RNA to the same location in the DNA sequence and makes a cut across both strands of the DNA. Researchers just need to program it, and it can cut out certain genes - or add new ones - far more cheaply and quickly than any previous genetic tools. Since the potential of the system was discovered back in 2012, it's already been tested widely in animals, and in January this year, it was used to successfully treat its first disease in mice, Duchenne muscular dystrophy. There have also been CRISPR experiments done in non-viable human embryos, which were never brought to term. But this is the first time that cells edited by CRISPR have ever been injected into an adult human. The trial was carried out at the West China Hospital, and involved a patient with aggressive lung cancer. The researchers extracted the patient's immune cells from a blood sample and then used CRISPR editing to disable a gene in them. The gene that was turned off codes for a protein called PD-1, which usually slows down a cell's immune response, allowing cancer to grow out of control. These PD-1-free immune cells were then cultured in the lab and injected back into the patient. The aim is that they'll now proliferate in the patient's body and attack and destroy cancerous cells. It's still early days, but lead researcher Lu You told David Cyranoski at Nature that the initial treatment went well, and the patient is now ready for a second injection. Across the duration of the trial, which received ethics approval in July, the team aims to treat a total of 10 people, with between two and four injections of genetically edited immune cells each. And they're not the only ones planning to use CRISPR on humans - the US has a similar trial against various cancers in the works, which is scheduled to start in early 2017, and has been funded by Napster billionaire Sean Parker. And China has another three clinical trials planned for March 2017 https://en.wikipedia.org/wiki/Genome_editing http://www.yourgenome.org/facts/what-is-crispr-cas9
Просмотров: 2136 The Marijuana Garden
CRISPR May Cure All Genetic Disease
Want a disease-free life or a baby with blue eyes? CRISPR might be mankind's gene editing Get Out of Jail Free card, and it's on its way. https://www.youtube.com/exploringtheunbeatenpath Subscribe to our Channel: https://goo.gl/RgDszL Read the full story at: https://www.interestingshit.com/science/crispr-gene-editing-tool-tomorrow-right-now/ Check out our most popular video: https://www.youtube.com/watch?v=7W83K5Ly-tY Check out more Interesting Shit: The MS-Suffering Wonder Woman of Marathon Running https://youtu.be/Q6mo3_7oRg4 10 Things in Nature That Look Like Vaginas #NSFW https://youtu.be/nvx9i1vRaVs More Interesting facts about Crispr: - CRISPR is making gene editing so simple it’s almost scary. - CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. - It is a simple tool scientists can use to edit and repair human, animal and plant genes. - Allowing them to fine-tune the genetic building blocks that make us who we are. - Unwanted genes that carry cancer, diabetes, even HIV-can be removed and replaced. - Researchers are predicting it could wipe out all inherited diseases within 20 years. - Still in its infancy, CRISPR won’t see widespread human trials for several years. - CRISPR is estimated to be 150 times cheaper than other gene modification techniques. - The components needed to edit the genes cost just $30 USD. - CRISPR technology isn’t just found in the lab - it’s already being used on crops. - The technology has raised concerns about potential abuse. Including the custom-building of embryos with specific gene strands for hair and eye color. - A controversial, genetically-modified playing field for everyone. About Interesting Shit? We are committed to telling the world’s greatest stories about history, geography and world culture. We are a group of insanely curious individuals who are inspired by the beautiful world that we live in. The digital world has not been able to digitize all things, and so much of the stories we aim to tell are the ones that are not well known today. The stories we tell blow our minds, and we hope that will blow your mind too. Subscribe to our newsletter so you can receive these stories regularly. Interesting Shit is an Educational Media Company with the aim of producing snack-able handmade content, and massively distributing this content on the most popular social platforms. Our aim is to connect curious readers with the world’s greatest stories and to build a community around history, geography and world culture. Visit our official site at: https://www.interestingshit.com/
Просмотров: 2083 INSH
Cell-free DNA Analysis and Cancer Treatment
The capacity to detect new cancers, treatment-resistant variants, and tumor heterogeneity by noninvasive technology on the basis of tumor DNA in the blood promises to revolutionize cancer detection, prevention, and treatment. Application of Cell-free DNA Analysis to Cancer Treatment: https://nej.md/2yKlbhN
Просмотров: 908 NEJMvideo
Developing a Permanent Treatment for Lactose Intolerance Using Gene Therapy
For more than half a decade I've suffered from lactose intolerance. If I consumed even the smallest amounts of lactose I'd be violently ill within the hour. So as I was choosing my university I vowed that one day I'd fix it. Recently my friend Gabriel Licina, renowned biohacker and genetic engineer, gave me access to the tools and materials I needed to make a therapy that could potentially fix the issue. The therapy uses a virus called an AAV to deliver DNA that codes for the enzyme that breaks down lactose. When packaged into a pill and ingested, the virus should induce my intestine to produce lactase, effectively restoring lactose tolerance. This project was based on research done by other scientists and I've included links to all the papers below. I've also included links to all of the places I got the viral DNA kits from. The other reagents and media were all purchased from the thermofisher catalogue. I'm also working on a writeup of this procedure and will hopefully publish a paper on the results once I've collected more data. I know that so far my sample size is still only N=1 but my life has changed from this project and I wanted to share my progress. I'm not going to make any claims about the project other than my life seems to have improved. This is for educational purposes only. Do not attempt anything you see, unless you are an experienced biologist. __________________________________________________________________ Resources: Original paper: http://sci-hub.tw/10.1038/2625 pAAVLacz Plasmid: https://www.cellbiolabs.com/paav-lacz-control-plasmid AAV kit: https://www.cellbiolabs.com/aav-2-cmv-expression-system __________________________________________________________________ Interested in some sweet science themed designs for your wardrobe or wall? Click the link below to see all the great items currently being offered: https://www.redbubble.com/people/chironex?asc=u __________________________________________________________________ Want to support the show and my research? Check out my patreon at: https://www.patreon.com/thethoughtemporium __________________________________________________________________ My Social Media Pages: Instagram: https://www.instagram.com/thethoughtemporium/ Facebook: https://www.facebook.com/thethoughtemporium/ Twitter: https://www.twitter.com/TTEchironex Website: http://thethoughtemporium.com/ __________________________________________________________________ As always, thanks to my awesome Patrons for helping to make these video possible. Thanks to: -Terry Fuller -Jason Dunham -Anita Fowler -Jonas Abreu -cataract bumblesnatch
Просмотров: 122143 The Thought Emporium
CAR T-cell Therapy: A Hopeful Option in Cancer Treatment (Full Video)
The Leukemia & Lymphoma Society (LLS) invites patients and caregivers to learn more about: • CAR T-cell therapy as an emerging treatment option • The impact of clinical trials in the advancement of treatment for blood cancer patients Please provide your feedback after viewing the video. Visit http://www.LLS.org/educationvideos to access additional patient education videos. For disease, treatment and support information, please call an LLS Information Specialist at (800) 955-4572 or email infocenter@LLS.org. For LLS patient education programs, please visit http://www.LLS.org/programs. For professional education programs, visit http://www.LLS.org/professionaled. We hope you find this program informative and helpful. Support for this video provided by Juno Therapeutics, Kite Pharma, and Novartis Oncology.
Просмотров: 18880 Leukemia & Lymphoma Society
Cancer therapy by Genetic engineering , HEALTH EDUCATION , INFECTION CONTROL (ICSP) , URDU / HINDI .
http://infectioncontrolsociety.org Health awareness programme by I.C.S.P.
Просмотров: 734 icsp94
How Machine Learning is Fighting Cancer
Be one of the first 73 people to sign up with this link and get 20% off your subscription with Brilliant.org! https://brilliant.org/realengineering/ New vlog channel: https://www.youtube.com/channel/UCMet4qY3027v8KjpaDtDx-g Patreon: https://www.patreon.com/user?u=2825050&ty=h Facebook: http://facebook.com/realengineering1 Instagram: https://www.instagram.com/brianjamesmcmanus Twitter: https://twitter.com/Fiosracht Discord: https://discord.gg/s8BhkmN Get your Real Engineering shirts at: https://store.dftba.com/collections/real-engineering Credits: Writer/Director: Stephanie Sammann (https://www.stephanie-sammann.com/) Narrator/Co-Director: Brian McManus Co-Director: Mike Ridolfi (https://www.moboxgraphics.com/) Sound: Graham Haerther (https://haerther.net/) Thumbnail: Simon Buckmaster https://twitter.com/forgottentowel References: [1] https://medium.com/netflix-techblog/artwork-personalization-c589f074ad76 [2] https://static1.squarespace.com/static/5443d7c7e4b06e8b47de9a55/t/5a240960c8302530429f629e/1512311141147/JYI_Dec2017_122to124*.pdf [3] http://sci-hub.tw/10.1016/j.gene.2016.01.023 [4] https://www.explainthatstuff.com/introduction-to-neural-networks.html [5] https://www.youtube.com/watch?v=aircAruvnKk&feature=youtu.be [6] https://hackernoon.com/gradient-descent-aynk-7cbe95a778da [7]https://towardsdatascience.com/machine-learning-fundamentals-via-linear-regression-41a5d11f5220 [8] http://mccormickml.com/2014/03/04/gradient-descent-derivation/ [9]https://towardsdatascience.com/understanding-learning-rates-and-how-it-improves-performance-in-deep-learning-d0d4059c1c10 [10] https://news.microsoft.com/stories/computingcancer/ Music by Epidemic Sound: http://epidemicsound.com/creator Song: Milo's Journey - Sum Wave Strange Tech 11 - Gunnar Johnsén Momentum 5 - Gunnar Johnsén Ocean Lanes 2 - Gunnar Johnsén Nightwaves 1 - Gunnar Johnsén Reflective Moods 2 - Gunnar Johnsén Thank you to my patreon supporters: Adam Flohr, darth patron, Henning Basma, Karl Andersson, Mark Govea, Hank Green, Tony Kuchta, Jason A. Diegmueller, Chris Plays Games, William Leu, Frejden Jarrett, Vincent Mooney, Ian Dundore, John & Becki Johnston. Nevin Spoljaric, Kedar Deshpande
Просмотров: 204326 Real Engineering
BIOLOGY: Genetic Engineering - Robin Hesketh
Good News for cancer therapy. Trials show genetic engineering of T-cells in the treatment of B-Cell Acute Lymphocitic Leukemia works.
Просмотров: 417 Hay Levels
Gene Therapy Explained
Many diseases have a genetic basis, which means that the disease is caused by mutated genes which provide incorrect instructions that cause the cell to produce abnormal protein, or disable production of the protein completely. In gene therapy, a functional copy of the gene is delivered into a patient’s own cells. Normal protein that is produced from a functional gene corrects the underlying cause of the disease, and may provide restorative disease-modifying effects. Gene therapy uses engineered viruses to deliver genes into cells, such as adeno-associated virus (AAV) vectors, which are especially well suited for treating retinal diseases. Genetic defects in the eye can cause vision loss or blindness, and gene therapy can provide a long-term therapeutic benefit. This video explains how gene therapy, delivered by AAV vectors, works. For more info, visit www.agtc.com.
Просмотров: 108699 AGTC
The Future Of Cancer Cures
Andre Watson, the CEO & Founder of Ligandal, sat down with Bart Chilton as they discussed how gene editing could help fight diseases! Follow us on Twitter: https://twitter.com/RT_BoomBust https://twitter.com/bartchilton?lang=en Check us out on Facebook -- and feel free to ask us questions: http://www.facebook.com/BoomBustRT
Просмотров: 216 Boom Bust
Using Viruses to Cure Cancers by - 101Space (Episode 05)
Khalifa Gnieber, a third year medical student at LIMU, goes in depth about how scientists have been able to utilize the Zika virus in treating patients with Glioblastoma Multiform (An aggressive Cancer) due to its unique pathogenesis, and how we can achieve much more thanks to genetic engineering.
Просмотров: 185 Cases 101
CRISPR Cas 9: cancer treatment
This video is about CRISPR cas 9
Просмотров: 1821 Tom M
ILLUMINATI Virus Cancer Cure: ' I AM LEGEND' Becomes Reality
While watching the Nightly news on 8/10/11 I saw them announce that they have Genetically Engineered a new cancer cure, after watching the broadcast I felt as if i had seen that news broadcast before....and I had.....it was in the movie 'I AM LEGEND' . Mankind has become TOTALLY corrupt and they (whoever you want to call them: illuminati masons globalist Annunaki greys reptilians government etc.) plan on mutating/corrupting man kind into their OWN image!!! Death of Antibiotics: Rise of NDM 1 http://www.watchnpray.net/wnpblogtop10.aspx?categoryId=4 Additional TAGS: Antichrist Armageddon conspiracy theory H1N1 swin flu shot virus pandemic contgion Contagious Montauk Beach monster plum island virus genetic engineering modification GMO GM Georgia Guide stones rosicrucian age of aquarias Contagion 2012 doomsday cure for cancer medical industrial complex coruption in health industry Jesse Ventura Jane Bürgermeister H3N2 Avian H5N1 HIV AIDS full blown African American disease healthy sick Vaccine 9/11 Illuminati Freemasonry Freemason Scientology Princehall epidemic epidemia quarantine North American union Jordan maxwell Alex Jones Infowars David Icke Enigma tv Bob Dean Richard Hogland Leo Zagami John Lear Darkside Moon BaseApollo 18 Apollo 20 mummar kadafi libya egypt terrorism war politics Barack Obama Dick Cheney Bush administration NWO New World Order Rockeffeller Bill Clinton Shift 911 inside job holy grail bloodline Messiahbishop, pastor, prophet, prophetess, apostle, evangelist, church, tbn, dianetics, scientology, witchcraft, COGIC, baptist, methodist, episcopal, catholic, catholicism, charismatic, pentecostal, cult, apologetics, islam, muslim, israel, apologetics, eternal security, spiritual warfare, false teacher, false prophet, antichrist, prosperity, dominion, Jehovah, Jesus, Jim Jones, Ed Young, Juanita Bynum, Thomas Weeks, Rick Warren, Eddie Long, Creflo Dollar, False Preachers, preaching, church, False Prophets Anti Christ, Benny Hinn, T.D. Jakes, Robert Schuller, Jamal Bryant Marilyn Hickey, Paul Crouch, Jan Crouch, Rod Parsley, Carlton Pearson, Kenneth Copeland, Gloria Copeland, John Hagee, Jessie Duplantis, Oral Roberts, EW Kenyon, Kenneth Hagin, Frederick Price, Tony Alamo, Roy E. Brown Full Gospel Baptist Church International Paul S. Morton J Delano Ellis Neil C Ellis Darryl S Brister Jack Van Impe, Joyce Meyer, Morris Cerullo, Cynthia Okemmuo Peaceful Zion Clarence McClendon Dewey E. Lane Paula White, Kim Clement, Mark Chironna, Aleister Crowley, Jack Van Impe, Rudolph B. Lewis Jack Hayford, Lord Maitreya, Dalai Lama, Joseph Prince, Al Sharpton, Sherman Allen, Billy Graham, Firpo Carr, E. Bernard Jordan, Dorinda Clark Cole, Clark Sisters, gospel music, atlanta, georgia, Roman Empire matrix Johannism symbolism
Просмотров: 26177 watchNpraydotNet
Chinese Researchers Inject Cancer Patient with CRISPR Gene-Editing Cells
This trial at a university in Chengdu is the first time a patient has been injected with CRISPR cells programmed to fight cancer
Просмотров: 3005 Global1 News Network
CANCER & STRESS - Bruce Lipton
LAST CHANCE to Join Broadcast Yourself: https://londonreal.tv/by FREE LIVE MASTERCLASS: https://londonreal.tv/masterclass/ FREE PODCAST LAUNCH GUIDE: https://londonreal.tv/m/by-lm2/ Bruce Lipton - Biology Of Belief Watch the Full Episode for FREE only at: https://londonreal.tv/bruce-lipton/ Public Release on 10th-Sep-2017) SUBSCRIBE ON YOUTUBE: http://bit.ly/SubscribeToLondonReal Bruce H. Lipton, PhD is an internationally recognized leader in bridging science and spirit. Stem cell biologist, bestselling author of The Biology of Belief and recipient of the 2009 Goi Peace Award, he has been a guest speaker on hundreds of TV and radio shows, as well as keynote presenter for national and international conferences. Dr. Lipton began his scientific career as a cell biologist. He received his Ph.D. Degree from the University of Virginia at Charlottesville before joining the Department of Anatomy at the University of Wisconsin’s School of Medicine in 1973. Dr. Lipton’s research on muscular dystrophy, studies employing cloned human stem cells, focused upon the molecular mechanisms controlling cell behavior. An experimental tissue transplantation technique developed by Dr. Lipton and colleague Dr. Ed Schultz and published in the journal Science was subsequently employed as a novel form of human genetic engineering. In 1982, Dr. Lipton began examining the principles of quantum physics and how they might be integrated into his understanding of the cell’s information processing systems. He produced breakthrough studies on the cell membrane, which revealed that this outer layer of the cell was an organic homologue of a computer chip, the cell’s equivalent of a brain. His research at Stanford University’s School of Medicine, between 1987 and 1992, revealed that the environment, operating though the membrane, controlled the behavior and physiology of the cell, turning genes on and off. His discoveries, which ran counter to the established scientific view that life is controlled by the genes, presaged one of today’s most important fields of study, the science of epigenetics. Two major scientific publications derived from these studies defined the molecular pathways connecting the mind and body. Many subsequent papers by other researchers have since validated his concepts and ideas. Dr. Lipton’s novel scientific approach transformed his personal life as well. His deepened understanding of cell biology highlighted the mechanisms by which the mind controls bodily functions, and implied the existence of an immortal spirit. He applied this science to his personal biology, and discovered that his physical well-being improved, and the quality and character of his daily life was greatly enhanced. Dr. Lipton has taken his award-winning medical school lectures to the public and is currently a sought after keynote speaker and workshop presenter. He lectures to conventional and complementary medical professionals and lay audiences about leading-edge science and how it dovetails with mind-body medicine and spiritual principles. He has been heartened by anecdotal reports from hundreds of former audience members who have improved their spiritual, physical and mental well being by applying the principles he discusses in his lectures. He is regarded as one of the leading voices of the new biology. SUBSCRIBE ON YOUTUBE: http://bit.ly/SubscribeToLondonReal FREE FULL EPISODES: http://londonreal.tv/episodes London Real Academy: BUSINESS ACCELERATOR: https://londonreal.tv/biz LIFE ACCELERATOR: https://londonreal.tv/life BROADCAST YOURSELF: https://londonreal.tv/by SPEAK TO INSPIRE: https://londonreal.tv/inspire #LondonReal #LondonRealTV
Просмотров: 17537 London Real
How GMOs are Made - Genetic Engineering 101
Genetic Engineering 101 Ever wonder how GMOs are actually made? ZBiotics' Zack Abbott explains. http://www.zbiotics.com/ https://www.facebook.com/ZBiotics/
Просмотров: 280 ZBiotics
Genetic Analysis of Breast Cancer Could Change Treatment
Research published by Nature shows there are four distinct types of breast cancer and that genetic changes occurring as cancer cells spread are vastly different for each type. Judy Woodruff talks to National Cancer Institute's Dr. Harold Varmus for more on what the research could mean for treatment in the future.
Просмотров: 1806 PBS NewsHour
Immune-based Gene Therapy for Cancer
MSKCC scientists are engineering immune-system cells called T-cells so that they can identify and destroy leukemia and prostate cancer cells.
Просмотров: 2315 Memorial Sloan Kettering
Can CRISPR Cure Cancer? What 2017 Research Says...
Crispr cas9 is one of the most recent revolutionary discoveries in science and medicine. Many think it has the potential to cure diseases someday. In this video, we take a look at what strides were made in 2017 with crispr research. Please check out my blog and social media! http://www.scienceresponsibly.com Twitter: sciresponsibly Instagram: scienceresponsibly Facebook: https://www.facebook.com/Science-Responsibly-205186949922795/?ref=bookmarks *This video was not made by medical professionals and should NOT be taken as medical advice.
Просмотров: 1190 Science Responsibly
ACGT - Dr. Michel Sadelain on cell and gene therapies for cancer treatment
Просмотров: 1470 ACGTFoundation