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Ciclosporin
 
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Dropping Drugs presents an information burst covering Ciclosporin which is branded as; Neoral Gengraf Sandimmun Sandimmune Restasis Consupren Equoral Sigmasporon Neoimmun Cicloral Zinograf Cyclosporin Comments are active, but are not actively monitored. If you wish to contact us please use the email address attached to this account. A pharmacist has reviewed and released this episode. Information is intended for a United Kingdom audience and supports common travel requirements. All technical definitions are those defined by European Medical agency (ema) but where possible or where it is the norm those relevant to best practice have been used as defined by the federal drug administration (FDA). Common and less common adverse effects are listed to highlight the health professionals opinion of the most commonly observed side effects. Not all documented adverse effects are reported. Where legal status for a medicine varies, the most common treatments legal status is often used to indicate the need for a prescription. Where national differences apply national flags may be used to indicate such a region All rights to Brand names are retained by the respective companies. Carefree Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 3.0 License http://creativecommons.org/licenses/by/3.0/ The royal pharmaceutical Society of Great Britain owns rights to a registered service mark – ‘Pharmacy Green Cross’. Dropping drugs was produced on behalf of AJI Technology who reserve all rights 2016. Patients are advised to seek individual medical advise and read the patient information leaflet prior to initiation of any treatment Episode 6
Просмотров: 1867 Dropping Drugs
Xiidra vs. Restasis - Dr. Travis Zigler Discusses
 
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Benefits of Xiidra as Opposed to Restasis Xiidra has just been introduced to dry eye sufferers, the first new treatment for that ailment in 13 years. Restasis was the last new one and was approved by the FDA in 2003. But there has been a lot of research in those years and 2003 when Restasis was first introduced, people didn’t really know much about dry eye as a condition. What they knew of it was more of a description of its symptoms. So what does Xiidra provide that Restasis doesn’t, and vice versa? Xiidra’s Benefits Over Restasis Restasis is a pharmaceutical-grade product but is only approved for the treatment of dry eye and it’s primary benefit is that it helps people with dry eye eventually begin to recover higher quality eye moisture. Xiidra has been approved not just for the treatment of dry eye signs, but for its symptoms as well. It sounds like a technicality, but it’s a big one! Xiidra treats the symptoms such as dryness, redness, pain, headaches, irritation, and the like, and some patients experience improvements within two weeks, more by six weeks, and most by 12 weeks of use. That’s a big improvement on Restasis, which is recommended to be used for six months before most patients see improvement, and then it is only in increasing tear production. The six-month issue has been one of the big problems for those using Restasis and many quits using it before they reach the benefit stage. Buying Restasis at the cash price (not considering insurance coverage) usually, runs about $400 per month for people using two drops per day per eye. Side Effects As mentioned, some were using Restasis experience a burning sensation when they apply the drops. There are some who have a similar response to Xiidra, but the numbers appear lower – at least from the trials run to get FDA approval. Those numbers could climb as Xiidra begins to see more widespread use, but it does not seem to be a huge factor. Other side effects experienced by those using Xiidra during the trial phase, but at a much lesser level, include a strange or bad taste in the mouth and blurry vision right after application of the drops. Also, no tests were done with women who were pregnant or breastfeeding. For those who are breastfeeding or pregnant, check with your doctor, but it’s probably better to avoid the use of any medications during that time. Contact Lenses Restasis users are generally told not to wear contact lenses while using their eye drops. Xiidra users can still wear contacts; they just have to remove them before putting the drops in their eyes and then wait at least 15 minutes before putting the lenses back in. Even easier, you can just use Xiidra before inserting the lenses in the morning and then again after taking them out at night. Most people believe Xiidra is a step up from anything else available, and time will tell if this is the case. Have you tried Xiidra yet? What about Restasis? Any success stories out there?
Просмотров: 14077 The Dry Eye Show
Klarity C for Dry Eyes
 
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A patients review of the drops from Imprimis. FDA Approved Cyclosporine-based formulations can help alleviate the symptoms of dry eye.
Просмотров: 143 Parbhu MD
5 Treatments That Can Help Dry Eyes
 
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Thank you for watching **Useful Information** * From providing a useful information channel. 5 Treatments That Can Help Dry Eyes How to treat dry eye Millions of Americans suffer from stinging, burning, blurry, and gritty-feeling eyes due to dry eye syndrome. While everyone can have dry eyes once in a while, those folks have a chronic problem due to inadequate tear production. Some people are at higher risk of dry eye than others. (Here are some of the most common dry eye risk factors). The good news is that there are several ways to treat dry eye, including natural remedies you can try at home, over-the-counter drops, and even prescription products and procedures that get at the root of the problem. What is important is to not ignore your symptoms. Because tears contain antibodies, lubricants, and nutrients that protect the eye, leaving these eye symptoms untreated for too long can damage your eyes. Consider your medications Often dry eye is a side effect of medication, everything from allergy meds to painkillers to blood pressure drugs. When you seek treatment for your eye symptoms, tell your doctor about any other meds you are taking. She can tell you if one of these (here are 14 dry eye-causing medications) could be triggering your dry eye. You might be able to switch to a different medication that doesn't cause dry eye. If that's not possible, read on. Plug your tear ducts Tear ducts or puncta are located at the inner corners of your upper and lower eyelid. Their function is to drain tears away from the eye into the nose. Plugging the ducts with sterile lacrimal plugs or punctal plugs can keep both your own tears and artificial tears in the eye. "Basically you're just closing the duct that drains tears out of your eyes," explains Cushing. "Usually it's reversible with a silicone plug but you can actually cauterize and close the punctum permanently." Wear therapeutic contact lenses Although regular contact lenses can actually cause dry eye if worn over the long-term, special contact lenses called scleral lenses or bandage lenses can fix the problem by protecting the surface of the eye and keeping moisture from seeping away. Eat more omega-3s Adding more omega-3 fatty acids to your diet may also help relieve dry eye. Dietary sources include salmon, sardines, tuna, walnuts, and flaxseed. Ask about prescription meds In addition to over-the-counter preparations, there are prescription remedies available. There are eye drops that contain the anti-inflammatory compound cyclosporine (Restasis) and in 2016, the FDA approved a new type of dry eye treatment called lifitegrast ophthalmic solution (Xiidra). Corticosteroids, which also control inflammation, are also available in eye drop form, although these are generally not recommended for long-term use.
Просмотров: 244 Useful Information
BRAND NEW HAIR LOSS CURE in 2018 WAY-316606! Legit or Not?
 
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▶️Subscribe to my VIP list and Get Your FREE Copy of my e-Book: https://mattdominance.com/ _________________________________________________ ▶️Natural HAIR GROWTH Treatment that actually works: https://www.regrowz.com use my code 10CAREGROWZ22 for 10% off _________________________________________________ ▶️Best DHT Blocking Shampoo on the market I use daily: https://bit.ly/2Opm7kE _________________________________________________ Brand new hair loss cure in 2018 and when it will reach the market and the shelves of our pharmacies? It should come in form of a shampoo. So fat it was tested on 40 different hair grafts provided by 40 random hair transplant patients. How fast can you expect new hair growth? Watch this video, like, comment and subscribe! 🔴 STUDIES: ▶️Cyclosporine A http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2003705 ▶️What are Wnt pathways? https://medicalxpress.com/news/2016-07-wnt-shown-critical-role-hair.html Moreover, while CsA has major potential side effects, the same is not true for WAY-316606. CsA is an immunosupresant, WAY-316606 is a non-immunosppressive, chemically unrelated agent. ➤My hair transplant clinic: https://elithairtransplant.com
Просмотров: 39108 Matt Dominance Hair Transplant
Ciclosporin
 
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Ciclosporin Ciclosporin also cyclosporin and cyclosporine is an immunosuppressant drug widely used in organ transplantation to prevent rejection It reduces the activity of the immune system by interfering with the activity and growth of T cells34 It was initially isolated from the fungus Tolypocladium inflatum found in a soil samples in 1969 from Norway, by Hans Peter Frey5 Most peptides are synthesized by ribosomes, but ciclosporin is a cyclic nonribosomal peptide of 11 amino acids and contains a single D-amino acid, which is rarely encountered in nature6 Ciclosporin was discovered in 19767 It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system8 Contents 1 Medical uses 2 Adverse effects 3 Mechanism of action 4 Metabolism and metabolite activity 5 Biosynthesis 6 History 7 Formulations 8 Name 9 Research 91 Neuroprotection 92 Cardiac disease 10 Other animals 11 See also 12 References 13 External links Medical uses Ciclosporin is approved by the FDA to prevent and treat graft-versus-host disease in bone-marrow transp Ciclosporin Click for more; https://www.turkaramamotoru.com/en/ciclosporin-24417.html There are excerpts from wikipedia on this article and video
Просмотров: 14 Search Engine
WAY-316606: THE NEXT HAIR LOSS CURE?
 
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CAN THIS BE THE NEXT HAIR LOSS PREVENTION MEDICATION? FIND OUT NOW! http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2003705 ================================== Welcome to my Youtube channel Hairliciously. In this channel, I will be taking you on a journey of my FUE hair transplant progress. Towards the end of November 2016, I had a 1700 FUE hair transplant done in South Korea at Motion Clinic (http://en.motionclinic.kr) to lower my hairline and to fill in my receding temples. The FUE hair transplant procedure took me about 7-8 hours to complete and cost me approximately $5000 USD. I will be doing daily updates on my hair transplant progress, so feel free to subscribe and ask any questions you have. Thanks for visiting! Please like, comment and subscribe! :) My hair transplant clinic: http://en.motionclinic.kr My website: https://www.Hairliciously.com *******Buy Your Derma Roller HERE!******* http://hairliciously.com/store/ ======================================= Products I am using to supplement my FUE hair transplant: 1. Finasteride 1mg/day (generic brand for Propecia/Proscar) - Finasteride is approved by the FDA for male pattern baldness and is effective in slowing hair loss for men. 2. Biotin 10,000mcg/day - Biotin is effective in thickening hair, nails, and beautifying the skin. I've noticed thicker and stronger hair after using Biotin for the past few months. 3. Vitamin D 3,000IU/day - Vitamin D helps maintain a healthy body 4. Minoxidil (Rogaine) - Minoxidil slows hair loss progression and promotes hair regrowth. I've noticed that using Minoxidil helped me grow my transplanted hairs a lot more quicker. 5. Pumpkin Seed Oil 1000 mg 6. Low Level Laser Therapy (LLLT)
Просмотров: 34504 hairliciously
Side effects include ... a potential treatment for baldness
 
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Story highlightsA compound developed to treat osteoporosis is found to promote hair growth Human clinical trials are next step for this drug (CNN)Though it's normal to lose up to 100 hairs from your scalp every day, excessive hair loss is distressing. But a drug originally developed to treat osteoporosis may soon help those who want to treat or even reverse baldness, according to research published Tuesday in the journal PLOS Biology.The path to finding this new compound began with an immunosuppressive drug, cyclosporine A, that has been used since the 1980s to treat patients undergoing transplant surgery or struggling with autoimmune diseases. Promising resultsCyclosporine A has some severe side effects, including convulsions and diarrhea, yet some patients have experienced something quite unusual: unwanted hair growth. Sensing a possible answer to baldness, researchers from the University of Manchester's Centre for Dermatology Research decided to investigate by analyzing the drug's impact on gene expression.Trump is taking hair loss drug, doctor saysRead MoreThey found that cyclosporine A quiets a certain protein (commonly known as SFRP1) that inhibits hair growth. When the silencer is silenced, raucous hair growth occurs. The research team searched for another compound with a similar mechanism of action and found WAY-316606, which was developed to treat osteoporosis. After applying WAY-316606 to hair follicles in a lab, the researchers found that it did an even better job of growing hair than cyclosporine A. This "demonstrates that WAY-316606 is a promising new pharmacological promoter of human hair growth," the study authors wrote, adding that they expect any side effects to be less toxic than those of cyclosporine A. Drug reverses one baldness type; is male pattern next?The next step is clinical trials to see whether topical use of this compound is safe and effective for humans.'Not just an aesthetic thing'Dr. Doris Day, a dermatologist at Lenox Hill Hospital in NYC, said she feels hopeful that this research will result in a new medication and "bring us a step closer to finding permanent ways to help prevent hair loss and regrow hair."Day, who was not involved in the study, said she's seen "many strides" in hair loss research over the past decade with research focused on both the immune system and genetics. "Now, we have treatments that are available," she said. Originally, minoxidil was approved to treat high blood pressure, while finasteride was intended for the treatment of an enlarged prostate. Today, minoxidil is US Food and Drug Administration-approved for the treatment of both male and female pattern baldness; finasteride is FDA-approved for male pattern baldness and sometimes used off-label for hair loss in women.Drug gives bald man full head of hairMost recently, autoimmune drugs known as Janus kinase inhibitors -- JAK inhibitors -- have been found to produce a full head of hair in patients with moderate to severe alopecia areata,
Просмотров: 544 Health & Fitness
Humira allergic reaction, hidradenitis suppurativa, 3 month course gone bad
 
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6th shot went wrong got a bad reaction from it will be going back to the doctors and finding out soon .. Will upload a new video within couple of days .. Link for my previous video - http://youtu.be/w-YMAsUpA0M
Просмотров: 48635 Jay Quddus
केवल 48 घंटो में HAIR REGROWTH START कर देता है यह नया MEDICINE - DR ASHOK SINHA
 
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WAY 316606 IS VIDEO ME MAI EK AISE MEDICINE KE RESEARCH KE BARE ME BATANE JA RAHA HUN JO HO SAKTA HAI FUTURE ME BALDNESS KA SABSE EFFECTIVE TREATMENT HO . 8 MAY 2018 KO MANCHESTER UNIVERSITY KE DR NETHAN HOCKSHOW KA , PLOS BIOLOGY NAM KE JOURNAL ME EK ARTICLE PUBLISH HUA HAI ,IS ARTICLE KE AANE KE BAAD SCINTIFIC WORLD ME EK EXCITMENT HAI,BBC KO DIYE GAYE EK INTERVIEW ME DR NETHAN NE KHUD HI YE KAHA HAI KI UNHE IS MEDICINE SE KAFI UMMID HAI. AUR UNKA YE VISHWAS HAI KI YE MEDICINE BALD LOGON KE LIFE KO DEFINITLY BEHTAR BANAYEGA. SUN TABLOID ME DR HAWKES NE TO YAHAN TAK LIKH DIYA HAIN KI WO IS RESEARCH SE KAFI UMMID RAKHTE HAIN KUKI LAB TEST ME YAH MEDICINE SIRF DO DIN ME , DHYAN DIJIYE SIRF DO DIN ME HAIR FOLLICLE KE GROWTH KO START KAR DETA HAI AUR AGAR YE SUCCESSFUL HOTA HAI TO ISE GEL YA SHAMPOO JAISE SIMPLE FORMULATION ME USE BHI KIA JA SAKTA HAI. MAIN BAAT KAR RAHA HUN HAIR LOSS KI NAYI researched MEDICINE WAY 316606 KI. JI HAN NAAM THODA NUMERICAL HAI..AUR HO SAKTA HAI KI KUCHH NUMEROLOGIST NE YE CALCULATE BHI KAR LIYA HO KI YE MEDICINE SUCCESSFUL HOGA KI NAHI.JOKES APART …PER YE MINOXIDIL OR FINASTERIDE KE BAD SHAYAD SABSE PROMISING RESEARCH HAI. IS DISCOVERY KO UNHONE AUR AAGE BADHAYA. AB UNHONE 40 AISE LOGON KO CHUNA JINKA HAIR TRANSPLANT HO RAHA THA AUR UNKE EXTRACTED FOLLICLES KO LABORATORY CONDITION ME 6 DINO TAK WAY 316606 SE TREAT KIYA.YE FOLLICLES 2 DIN ME HI HAIR CYCLE KE ANAGEN YA GROWTH PHASE ME CHALE GAYE AUR UNKE HAIR SHAFT KA GROWTH BHI START HO GAYA. AMAZING NAHI. AB AISA LAG RAHA HOGA KI JINKE HAIR FALL HO RAHE HAI UNKE ACHHE DIN AA GAYE. LEKIN ABHI APNE EXCITEMENT KO ZARA CONTROL ME RAKHNA HOGA.KUKI YE EK STUDY HAI. SHAYAD BALDNESS KO KHATAM KARNE KI PRAKRIYA ME EK AUR KADAM. AB YE TO WAQT HI BATAYEGA KI SCIENTIFIC WORLD Ki YE HALCHAL HOPE HAI YA SIRF EK AUR HALCHAL. SAMAY SAMAY PER KUCHH HALCHAL HAMESHA HI HOTE RAHE HAI JAISE 2015 ME JAK INHIBIOTORS 2016 ME CYCLOSPORIN A NE BHI AISA HI EXCITEMENT PAIDA KIYA THA. ABHI WAY 316606 KE SUCCESS AUR SIDE EFFECT KI STUDY KE LIYE KAFI RESEARCH AUR CLINICAL TRAIL KI ZAROORAT HAI. AUR ABHI IS MEDICINE SE JUDE KAI SAWAL HAI, JAISE YE KAISE BAL PAIDA KAREGA TERMINAL YA VILLOUS , aise BAL KITNE SAMAY TAK CHALEGE, AUR UN BALON KI QUALITY KYA HOGI.AISE KAI SAWAL HAIN AUR IN SABHI SAWALON KE ANSWER TO HUME FUTURE ME HI MILENGE. PER AISA LAG RAHA HAI KI DR NATHAN NE BALDNESS KE LIYE EK PROMISING TREATMENT DHUNDH LIYA HAI . IS RESEARCH KE SATH DO POSITIVE POINTS HAI . PEHLA KI WAY 316606 OSTEOPOROSIS ME HUMANS ME USE KARNE KE LIYE ALREADY APPROVED HAI, TO SHAYAD YEH MEDICINE JALDI HI BALDNESS KE LIYE BHI APPROVE HO JAYE AUR DUSRA KI TEST BHI HUMAN HAIR FOLLICLE PE HUA HAI CHUHE YA GUINEA PIG KE BALON PER NAHI. RESEARCH PAPER STUDY KARTE SAMAY MERE MAN ME YE PRASHAN AAYA KI DR NETHAN NE TESTING KE LIYE DONOR AREA KE HAIR FOLLICLE KU SELECT KIYE, WO TO AISE BHI HEALTHY HOTE HAIN, MINIATURISATION TO FRONTAL PART ME HOTA HAI? TO THIN HO GAYE BALON KO KU NAHI SELECT KIYA. ANY WAY HE HAS DONE HIS RESEARCH. NOW ITS TIME TO WAIT AND WATCH. SHAYAD WAY 316606 HAIR REGROWTH KA HIGH WAY 316606 PROVE HO JAYE. YE TO HO GAYI MEDICINE RESEARCH KI BAT ..AB HAIR TRANSPLANT ME BHI KUCHH AISA HI GAME CHANGING Dr. Ashok Sinha To get the consultation you can contact us anytime for the hair fall treatment Hair Transplant Education Visit Us: https://hairtransplanteducation.com Call Us : +91 9595-676-676
Просмотров: 622889 Hair Transplant Education
Atopica for Dogs & Cats (Atopica Dermatitis)
 
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Atopica dermatitis is the most common allergic skin disease in dogs. Like human allergies, it's brought on by seasonal pollen and other airborne allergen. Only ATOPICA® (Cyclosporine capsules, USP) MODIFIED controls itching from the immune cell level. Plus, this nonsteroidal anti-itch option is FDA-approved for long-term use. learn more at www.californiapetpharmacy.com add us on: Facebook: http://www.facebook.com/calpetrx Twitter: http://twitter.com/#!/CalPetRX Pinterest: http://pinterest.com/CalPetRx Google Plus: https://plus.google.com/109664120783950213000/
Просмотров: 1647 CalPetRX
Orlistat Alli ⚠️ Don't use Orlistat Alli untill you see this
 
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For a limited time Best Offer= you can buy Alli ONLINE with NO prescription here==========https://amzn.to/2JqCF58 Alli (orlistat) is an over-the-counter medication used to help people lose weight. Studies have shown that Alli can help people lose more weight than dieting alone. The weight loss drug is intended for overweight adults ages 18 and older who also follow a reduced-calorie, low-fat diet. A stronger dose of the same active ingredient in Alli is available by prescription and is sold under the brand name Xenical. Xenical may also be recommended after weight loss surgery to help patients keep off the lost pounds. How Does Alli Work? Alli belongs to a class of drugs called lipase inhibitors. It blocks the intestines from absorbing about 25% of the fat that you eat. Fats that aren’t absorbed leave your body through bowel movements. Some data suggest that Alli helps reduce the amount of a particularly dangerous type of belly fat called visceral fat, which has been linked to type 2 diabetes, high blood pressure, heart disease, and stroke. CONTINUE READING BELOW YOU MIGHT LIKE VIDEO Should You Take a Weight Loss Pill? There are always new weight loss pills released, but are they a solution or just an illusion? Is Alli Right for Me? If you’re overweight, and dieting and exercise haven't worked for you, talk to your doctor about a weight management program that involves medication. But remember, you still must follow a healthy lifestyle that involves regular exercise and eating right. To determine if you’re overweight, you can calculate your body mass index (BMI) using your height and weight information. A BMI of 18.5 to 24.9 is considered a healthy weight. A BMI of 25 to 29.9 is considered overweight. How Do I Take Alli? Alli comes in capsule form. It’s taken by mouth three times a day, either with a meal that contains a little bit of fat, or up to one hour afterward. If you eat a no-fat meal, your doctor may tell you to skip your dose. Never take more medicine than recommended. It’s important to follow a low-calorie, low-fat diet while taking this medication. If you eat a lot of fatty foods, even just one high-fat meal like a greasy burger, you’re more likely to have uncomfortable digestive side effects. Choose lean cuts of meat and low-fat dairy products. In general, no more than 30% of your calories at each meal should come from fat. You’ll also need to take a daily multivitamin that contains vitamins A, D, E, K, and beta carotene while on this drug. The drug's fat-blocking properties also make it more difficult for your body to absorb these fat-soluble vitamins. Do not take vitamins and Alli at the same time of the day. When Shouldn’t I Take Alli? Always tell your doctor about all the medications you’re taking. Alli can interact with certain drugs, affecting their levels or how they work in your body, which could lead to life-threatening consequences. Check with your doctor if you’re taking warfarin (a blood thinner), diabetes or thyroid medications, or other weight loss drugs. In some cases, your dosages may need to be adjusted. Don’t take Alli if: You’ve had an organ transplant. Alli is known to interfere with drugs used to prevent transplant rejection. You’re taking cyclosporine. You’re not overweight. You’re pregnant or breastfeeding. For a limited time Best Offer= you can buy Alli ONLINE with NO prescription here==========https://amzn.to/2JqCF58
Просмотров: 119 diabetes reversal 4 ever
Restasis: Pros and Cons
 
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Просмотров: 739 Dr. Sam Berne
Ilaris: The Economics behind a new  heart Attack Prevention drug-And the BIG problem .
 
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Please watch: "(905) Mitochondria: Central Role in Aging 2018 (and how to reverse it)( warning - geeky)- FORD BREWER " https://www.youtube.com/watch?v=mTKM0Lh078A --~-- Join the PrevMed Community: https://mailchi.mp/1224fb9e00e7/prevmed_community The recent CANTOS TRIALS showed a significant decrease in heart attack and stroke. So what's the catch? There are a couple: 1. the drug Ilaris currently costs $200,000 pre year; and 2. in the CANTOS trial, there were as many deaths due to increased serious infections as there were lives saved from heart attack and stroke. About Dr. Brewer - Ford Brewer is a physician that started as an Emergency Doctor. After seeing too many patients coming in dead from early heart attacks, he went to Johns Hopkins to learn Preventive Medicine. He went on to run the post-graduate training program (residency) in Preventive Medicine at Hopkins. From there, he made a career of practicing and managing preventive medicine and primary care clinics. His later role in this area was Chief Medical Officer for Premise, which has over 500 primary care/ prevention clinics. He was also the Chief Medical Officer for MDLIVE, the second largest telemedicine company. More recently, he founded PrevMed, a heart attack, stroke, and diabetes prevention clinic. At PrevMed, we focus on heart attack and stroke and Type 2 diabetes prevention by reducing or eliminating risk through attentive care and state-of-the-art genetic testing, imaging, labs and telemedicine options. We serve patients who have already experienced an event as well as those have not developed a diagnosis or event. Our team of senior clinicians includes internationally recognized leaders in the research and treatment of cardiovascular disease, preventive medicine and wellness. We also provide preventive medicine by telemedicine technology to over 30 states. Contact Dr. Brewer at info@prevmedheartrisk.com or visit http://prevmedheartrisk.com.
Просмотров: 220 Ford Brewer
What does the FDA drug side actually do?
 
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The FDA is there in every single stage of clinical testing. There is no company that would want to do the job of the FDA nor could there be http://en.wikipedia.org/wiki/Clinical_trial http://www.webmd.com/alzheimers/news/20070716/curry-spice-may-counter-alzheimers Resveritrol http://www.npr.org/blogs/thesalt/2011/09/21/140669655/whats-in-that-wine-glass-may-not-prevent-aging-after-all?sc=fb&cc=fp
Просмотров: 1350 anubis2814
FEATURE -- USDA & FDA RELEASE FOOD SAFETY BROCHURES FOR THOSE AT-RISK
 
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The federal government is updating its food safety advice for those who are at increased risk for foodborne illness. The USDA's Bob Ellison has more.
Просмотров: 705 USDA
Mycophenolate mofetil: Immunosuppressive Drug Used to Prevent Organ Transplant Rejection
 
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Source: https://www.medindia.net/ For more information, Please visit: https://www.medindia.net/doctors/drug_information/mycophenolate_mofetil.htm Mycophenolate mofetil works by decreasing the body’s immune system and prevents the rejection of transplanted organ by protecting the organ from the attack of the immune system. Mycophenolate mofetil is a prescription drug that was first approved by U.S FDA on 3rd May 1995 to use for kidney transplantation. Mycophenolate mofetil is prescribed for preventing the rejection of the following organ transplants such as kidney, heart, and liver. Mycophenolate mofetil injections should be used only when the oral therapy is not possible. IV therapy of mycophenolate mofetil should be switched to oral treatment as early as possible. Please help us translate this video in your language to make it more universal and useful to your language community. We present useful and essential information on the drug mycophenolate mofetil that everyone should know when taking this drug. Use Medindia drug information to check drug to drug interactions if you are taking more than one drug. Share your comments if you are experiencing any unusual side effects.
Просмотров: 1221 Medindia Videos
Can Tacrolimus/ Prograf Make You Feel Lousy?
 
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“I feel lousy should I blame Tacrolimus/ Prograf?” The viewer went on the add “I feel fatigued, upset stomach, headaches, overall drained.” Depending on your symptoms probably yes, Tacrolimus Or Prograf Can Make You Feel Lousy. Even though Tacrolimus is one of the most important drugs we take post-transplant it can be the most problematic. More times than not despite the symptoms it is a necessary evil. Tac / Prograf is very important in helping to adjust your immune systems so you don’t reject your new organ. If your symptoms match some of the symptoms listed above you are probably about average. However, call your doctor right away if you notice any of the following side effects: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. Change in how much or how often you urinate, painful urination, bloody urine. Confusion, weakness, uneven heartbeat, trouble breathing, numbness in your hands, feet, or lips. Dizziness, lightheaded, fainting. Fast, slow, or pounding heartbeat. Fever, chills, cough, stuffy or runny nose, sore throat, body aches. Headache, vision changes, tremors, seizures, tingling or numbness. Increased thirst or hunger. Rapid weight gain, swelling in your hands, ankles, or feet. Skin changes or growths. Swollen glands in your armpits or groin. Unusual bleeding, bruising, or weakness. Weakness on one side, confusion, clumsiness, trouble thinking clearly. The Transplant Helper and this YouTube channel IS NOT DESIGNED TO, AND DOES NOT, PROVIDE MEDICAL ADVICE. All content including text, graphics, images, spoken word and information available on or through this YouTube channel are for general informational purposes only. The Content is not intended to be a substitute for professional medical advice, diagnosis or treatment. NEVER DISREGARD PROFESSIONAL MEDICAL ADVICE, OR DELAY IN SEEKING IT, BECAUSE OF SOMETHING YOU HAVE READ ON THIS WEB SITE. NEVER RELY ON INFORMATION ON THIS WEB SITE IN PLACE OF SEEKING PROFESSIONAL MEDICAL ADVICE. -~-~~-~~~-~~-~- Check Out Another Great Video: "Will An Opt Out Organ Donation Save Lives? | Presumed Consent" https://www.youtube.com/watch?v=LlNjaABfDqQ -~-~~-~~~-~~-~-
Просмотров: 3547 The Transplant Helper
Cure For Baldness? Hair Growth Stimulated As Drug's Side Effect
 
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Cure For Baldness? Hair Growth Stimulated As Drug's Side Effect: https://www.medicaldaily.com/cure-baldness-hair-growth-stimulated-drugs-side-effect-423997. Thanks for watching, subscribe for more videos. Baldness can be an unwanted and stressful change for both men and women, especially as options for treatment have been limited. But a new agent may have the potential to reverse hair loss, according to researchers from the Centre for Dermatology Research at the University of Manchester, England.The study was published in the open access journal PLOS Biology on May 8.Dr. Nathan Hawkshaw led the new Ph.D. project to develop new ways to safely but effectively treat androgenetic alopecia, which refers to male or female pattern baldness. While men tend to experience a receding hairline and patchy loss of hair at the back of their head, women can notice significant thinning of their hair.First, the research team decided to examine how an old immunosuppressive drug worked. The drug, known as Cyclosporine A (CsA), has been in medical use since 1983 in the form of eye drops, to prevent rejection of organ transplants, treating of rheumatoid arthritis and osteoporosis, etc. The drug has also been linked to a number of side effects such as headaches, vomiting, high blood pressure, and most interestingly, increased hair growth.Using human hair follicles donated by hair transplant patients, Dr. Hawkshaw and his team conducted a full gene expression analysis of the follicles when they were treated with CsA. It was found that the drug reduced the expression of a protein (SFRP1) which hindered the growth of tissues, including the hair follicles.The study found that the drug removed an inbuilt mechanism which would induce a brake on human hair growth. "When the hair growth-promoting effects of CsA were previously studied in mice, a very different molecular mechanism of action was suggested," Dr. Hawkshaw explained. "Had we relied on these mouse research concepts, we would have been barking up the wrong tree."Furthermore, the researcher found that WAY-316606, the original compound developed for treating osteoporosis, also appeared to target SFRP1. When WAY-316606 is applied to the balding human scalp, Dr. Hawkshaw said, it may promote hair growth to a similar magnitude as CsA but without any of the side effects."The fact this new agent, which had never even been considered in a hair loss context, promotes human hair growth is exciting because of its translational potential: it could one day make a real difference to people who suffer from hair loss."For the experiments, scalp hair follicles from over 40 patients were obtained through the means of a collaboration with British hair transplant surgeon Dr. Asim Shahmalak from Crown Clinic, U.K.The researchers stated that a clinical trial was the next necessary step to assess whether the drug could be safe and effective to use on hair loss patients. As of now, the most effective treatment for balding is opting for a hair transplantation surgery. Only two drugs (minoxidil and finasteride) were approved by the FDA for the treatment of balding, both o
Просмотров: 139 Hatsiw bagaus
Watch before you take Cyclosporin for HAIRLOSS (WAY-316606)
 
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So if you are looking into taking Cyclosporin then this video will prepare in what you need to know, for you crazy guys going to try an immune suppressant for HAIRLOSS, which is "proved" to work then this video will prepare you for the side effects you are to face. I am currently taking an immune suppressant (Azathioprine) and thought i'd give you a run down, so here goes? SPONSORS ~~~~~~~~ Check out anageninc the Sponsors of RU58841 (research purposes only) they are not responsible for any sides. https://www.anageninc.com Please also check out https://www.regenhair.co.uk they are full of great hair products, they provided me with hair covet and I am excited to be using it for you guys Hi. My Name is Sid. I produce youtube videos to entertain you as much as I can, I like to upload whatever content I enjoy making and don't have a niche, it's all about what is fun for me, so if you enjoy the content I create then be sure to SUBSCRIBE to show your support If you enjoyed some of the content and wish to help out please feel free to donate with the link below, your donations help out alot! Give me your pennies bro! https://www.paypal.me/Searching4sid How can I get involved? Well throw some ideas down and you could be responsible for the next video! Where can I contact you? Visit my page on facebook (Searching4Sid), you can let me know your thoughts, ideas, criticism and give some helpful advice to help improve my channel, also if you wish to take part in the videos you can let me know via my facebook page, if I approve of your awesome idea, surely we can work together to create cool content. Why should I help you create content? Helping me move forward with my youtube, will also help you move forward. You help me grow, I will help you grow, that's as simple as it gets. Why should I share your awesome content? Well I know I am not the greatest youtuber but with great practice comes great production? I guess? if you had a laugh just take two seconds to help me gain something from my hard work, if you do not then, that is fine, your view is more than enough for me, but if you do, ill be able to give out prizes and other cool stuff in the future and you could be a lucky winner ! Do you have other social networks I could follow? Well of course I do, just type Searching4Sid in google and you will see all my social networks. Here I'll give you a short link below so you can subscribe/follow in no time! Instagram ►https://www.instagram.com/searching4sid Twitter ►https://twitter.com/Searching4Sid Facebook ►https://www.facebook.com/Searching4sid Okay, that's all for now, see you guys in the next vi
Просмотров: 8288 Searching4Sid
WAY-316606 | REGROW HAIR IN JUST 2 DAYS | BRAND NEW HAIR LOSS CURE in 2018 |
 
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MY NEW CHANNEL: https://www.youtube.com/liftandpush CLINIC: HAIRFREE AND HAIRGROW CLINIC CONTACT: 7096844171 WEBSITE: www.hairfreeindia.com MY WHATSAPP: 8072772244 Hope you like this video. Thank you. | LIKE | | SHARE | | SUBSCRIBE | The recent study, carried out at by a team of scientists at the University of Manchester, looked at how the drug called ciclosporin might be used as a treatment for human hair loss disorders, such as male pattern baldness. So, considering the drug in question (ciclosporin) is generally used in the treatment of autoimmune conditions (such as rheumatoid arthritis, ulcerative colitis and psoriasis), how did this study come about? As Dr Holmes explains, ‘the investigators started their investigation on the basis of a longstanding observation - that ciclosporin (a drug used to suppress the immune system) causes (generally unwanted) hair growth on the body.’ ‘[The scientists] treated normal human scalp hairs with ciclosporin and then analysed the RNA (ribonucleic acid) produced by the follicles through microarray analysis, to assess what proteins may be involved in the action of ciclosporin in stimulating hair growth.’ ‘They found that secreted frizzled related protein 1 (SFRP1) was reduced in ciclosporin-treated hair follicles. They then investigated the action of this protein on hair follicles and found that it regulated the Wtn-signalling pathways that control the normal hair cycle. They then found that blocking the action of SFRP1 with WAY-316606 enhanced hair follicle growth.’ Finasteride and minoxidil are the two current treatments for androgenic alopecia and the science behind their efficacy is very different to that found to be working in WAY-316606. Dr Holmes says, ‘this finding is entirely new and offers the possibility that WAY-316606 may be novel treatment for some hair loss disorders. #hairguide4u #hairtransplantkabir
Просмотров: 78533 HAIR TRANSPLANT
New Transplant Drug Belatacept: Drug Research and Development
 
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Full story -- http://is.gd/zSlEFN -- Christian P. Larsen, Emory University, on the years of work that resulted in FDA approval of Belatacept, a breakthrough in transplant medicine. Background The Food and Drug Administration (FDA) has approved the drug Nulojix (belatacept) for the prevention of graft rejection after kidney transplants. Belatacept could be a less toxic alternative to calcineurin inhibitors, the drugs most transplant patients now rely on to inhibit their immune systems, but which can damage the kidneys and lead to high blood pressure and diabetes. This is the first time a new class of drugs has been developed for transplant since the 1990s. Belatacept has the potential to improve and simplify the medication regimens of kidney transplant recipients, and is also now being tested in experimental clinical trials for liver transplant and pancreatic islet transplant. Since the early 1990s, Emory surgeon-scientists Christian P. Larsen, MD, DPhil and Thomas C. Pearson, MD, DPhil have been searching for ways to promote immune tolerance of a transplanted organ. They played a leading role in discovering belatacept and driving its development, in collaboration with other investigators at Emory, including the Yerkes National Primate Research Center, and researchers at Bristol-Myers Squibb. More: "FDA Approves Transplant Drug That Preserves Kidneys, Avoids Toxicity" http://shared.web.emory.edu/whsc/news/releases/2011/06/fda-approves-transplant-drug-that-preserves-kidneys,-avoids-toxicity.html Emory Transplant Center http://emoryhealthcare.org/transplant-center/index.html
Просмотров: 1173 Emory University
Immune Pharmaceuticals (IMNP) Receives FDA Guidance for Phase III Pivotal Trial
 
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SCN's Jane King sits down with Dr. Daniel Teper, CEO & Founder of Immune Pharmaceuticals Inc. (NASDAQ: IMNP ), and Chief Medical Officer Dr. Monica Luchi, to discuss the biopharmaceutical company and its future outlook. http://www.immunepharma.com/ NEW YORK, Oct. 27, 2016 /PRNewswire/ -- Immune Pharmaceuticals (NASDAQ:IMNP) (STO: IMNP) (Immune) announced today that it has received guidance from the United States Food and Drug Administration (FDA) on a phase III study for Ceplene in combination with low dose IL-2 for the maintenance of remission in patients with Acute Myeloid Leukemia (AML). Ceplene/IL-2 has previously been approved in Europe and Israel following a successful phase III study with Leukemia Free Survival as the primary endpoint. The proposed phase III study design reviewed by the FDA focuses on overall survival as the primary endpoint, along with key secondary endpoints, including Leukemia Free Survival. The FDA also provided feedback relating to specific design elements of the phase III study, and with this framework, Immune plans to submit the final protocol for the phase III study in early 2017 and, upon approval, proceed with conducting a global Phase III Pivotal Overall Survival Study in AML maintenance of response with Ceplene/IL2. "We are very pleased with the positive outcome of our recent interaction with the FDA. Our path forward to proceed with a pivotal study following regulatory guidance of Ceplene/IL-2 meets our goal to address the urgent unmet medical need for remission maintenance therapy in AML," stated Monica Luchi, MD, Immune's Chief Medical Officer. About Immune Pharmaceuticals Inc.: Immune Pharmaceuticals Inc. (NASDAQ: IMNP) applies a personalized approach to treating and developing novel, highly targeted antibody therapeutics to improve the lives of patients with inflammatory diseases and cancer. Immune's lead product candidate, bertilimumab, is in Phase II clinical development for moderate-to-severe ulcerative colitis as well as for bullous pemphigoid, an orphan autoimmune dermatological condition. Other indications being considered for development include atopic dermatitis, Crohn's disease, severe asthma and Non-Alcoholic Steato-Hepatitis (NASH), an inflammatory liver disease. Immune recently expanded its portfolio in immuno-dermatology with topical nano-formulated cyclosporine-A for the treatment of psoriasis and atopic dermatitis. Immune's oncology pipeline includes Ceplene® which is in late stage clinical development for maintenance remission in Acute Myeloid Leukemia (AML) in combination with IL-2. Additional oncology pipeline includes Azixa® and crolibulin, Phase II clinical stage vascular disrupting agents, and novel technology platforms; bispecific antibodies and NanomAbs™. Maxim Pharmaceuticals Inc., Immune's pain and neurology subsidiary is developing AmiKet™ and AmiKet™ Nano™ for the treatment of neuropathic pain. For more information, visit Immune's website at www.immunepharma.com, the content of which is not a part of this press release.
Просмотров: 2805 BGN - Blockchain Global News
Jennifer's Story | Finding comfort in the journey
 
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Jennifer’s symptoms made her self-conscious, and she was ready for a change. Please keep reading for Approved Uses and Important Safety Info. Learn more about Otezla at: https://www.otezla.com Full Prescribing Information: http://bit.ly/OtezlaPI APPROVED USES Otezla® (apremilast) is a prescription medicine approved for the treatment of patients with moderate to severe plaque psoriasis for whom phototherapy or systemic therapy is appropriate. Otezla is a prescription medicine approved for the treatment of adult patients with active psoriatic arthritis. IMPORTANT SAFETY INFORMATION You must not take Otezla if you are allergic to apremilast or to any of the ingredients in Otezla. Otezla can cause severe diarrhea, nausea, and vomiting, especially within the first few weeks of treatment. Use in elderly patients and the use of certain medications with Otezla appears to increase the risk of having diarrhea, nausea, or vomiting. Tell your doctor if any of these conditions occur. Otezla is associated with an increase in depression. In clinical studies, some patients reported depression, or suicidal behavior while taking Otezla. Some patients stopped taking Otezla due to depression. Before starting Otezla, tell your doctor if you have had feelings of depression, or suicidal thoughts or behavior. Be sure to tell your doctor if any of these symptoms or other mood changes develop or worsen during treatment with Otezla. Some patients taking Otezla lost body weight. Your doctor should monitor your weight regularly. If unexplained or significant weight loss occurs, your doctor will decide if you should continue taking Otezla. Some medicines may make Otezla less effective, and should not be taken with Otezla. Tell your doctor about all the medicines you take, including prescription and nonprescription medicines. Side effects of Otezla include diarrhea, nausea, vomiting, upper respiratory tract infection, runny nose, sneezing, or congestion, abdominal pain, tension headache, and headache. These are not all the possible side effects with Otezla. Ask your doctor about other potential side effects. Tell your doctor about any side effect that bothers you or does not go away. Tell your doctor if you are pregnant, planning to become pregnant or planning to breastfeed. Otezla has not been studied in pregnant women or in women who are breastfeeding. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-332-1088. Please click here http://bit.ly/OtezlaPI for Full Prescribing Information.
Просмотров: 1240 Otezla apremilast
Transplant Drug Belatacept Shows Promise for Kidney Transplant
 
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Christian P. Larsen, Emory University, explains why Belatacept represents a breakthrough in transplant medicine. Background The Food and Drug Administration (FDA) has approved the drug Nulojix (belatacept) for the prevention of graft rejection after kidney transplants. Belatacept could be a less toxic alternative to calcineurin inhibitors, the drugs most transplant patients now rely on to inhibit their immune systems, but which can damage the kidneys and lead to high blood pressure and diabetes. This is the first time a new class of drugs has been developed for transplant since the 1990s. Belatacept has the potential to improve and simplify the medication regimens of kidney transplant recipients, and is also now being tested in experimental clinical trials for liver transplant and pancreatic islet transplant. Since the early 1990s, Emory surgeon-scientists Christian P. Larsen, MD, DPhil and Thomas C. Pearson, MD, DPhil have been searching for ways to promote immune tolerance of a transplanted organ. They played a leading role in discovering belatacept and driving its development, in collaboration with other investigators at Emory, including the Yerkes National Primate Research Center, and researchers at Bristol-Myers Squibb.
Просмотров: 311 Emory Healthcare
Natural Alternatives to 05 of the Most Common Prescription Drugs
 
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Natural Alternatives to 05 of the Most Common Prescription Drugs Subscribe To Get New Videos Daily: https://www.youtube.com/channel/UCi1zZ8_Q7yqKInXImLCLfXw Do you ever feel like you’re being held hostage by drug companies? All too often, people are made to believe that they have no options when it comes to taking a drug. If your doctor says you need a drug for a serious health problem, you might think it is the only thing you can do. You may feel frightened at the prospect of going against your doctor’s recommendations. You may be wary of seeking out natural alternatives. Drug safety is becoming a major concern among many health professionals. Reports to the FDA of serious adverse drug events, including deaths, have more than doubled in recent years. This is more than enough reason to do a little of your own research and explore natural alternatives before you get that prescription filled. Here are some drugs with clinically proven natural alternatives worth trying: #1. Ibuprofen vs. Curcumin: NSAIDs like Celebrex, aspirin and ibuprofen do reduce the pain and inflammation of osteoarthritis. However, they can irritate your stomach. There is concern that over time, they can make osteoarthritis worse. They can block the repair process. These drugs have been found to actually retard the growth of cartilage. What to Take: 1,000-1,500 mg a day. #2. Ambien vs. Melatonin: Ambien can be a great help for people who need it. But like other pills in its class, it creates dependence. You end up unable to sleep without it. Ambien has troubling side effects such as depression, amnesia and daytime drowsiness, headache and dizziness. What to Take: 3 mg before bedtime. Higher doses may cause wakefulness. #3. Restasis vs. Fish Oil: Restasis is the eyedrop form of the immune-suppressing and inflammation-suppressing drug cyclosporine. It’s used for chronic dry eyes. It works by suppressing the inflammation that disrupts tear secretion. Side effects include burning, redness and discharge. What to Take: 1,400 mg a day, or up to 6,000 mg a day if you have an autoimmune condition such as Sjorgren’s Syndrome. #4. Statins vs. Bergamot Orange: Statin drugs like Lipitor, Crestor and Lovastatin are called HMG-CoA reductase inhibitors. They are given this name because they reduce cholesterol by inhibiting an enzyme needed for cholesterol production. Side effects include liver and muscle damage. What to Take: 600 mg twice a day or 1,200 mg once a day. #5. Neurontin vs. Alpha Lipoic Acid: Neurontin (gabapentin) is an anti-seizure drug. It’s now popular for all sorts of pain related to nerve damage, including diabetic neuropathy. Side effects include drowsiness, confusion, dizziness and trouble walking. What to Take: 250-500 mg a day. Don’t let your doctor, or pharmaceutical ads, talk you into taking a drug you may not need before you have a chance to try to improve your through natural alternatives. It takes courage to turn away from the “simple” drug solutions that are so prevalent in our current way of thinking about medical problems. http://www.liveinthenow.com/article/10-drugs-with-great-natural-alternatives Watch Popular Videos : Is Gabapentin An Opioid ? https://youtu.be/jxlUvSd56sg The Best Exercises To Firm And Lift Your Sagging Breasts https://youtu.be/PxBT8yEqe_4 Top 10 Root Vegetables You Should Eat More Often https://youtu.be/wPfHuezTX3U She Applies Honey On Her Vagina And Results Will Shock You https://youtu.be/PT0W8He6n8s Indian Government Allocates 600 Crores Monster Moolah For TB Patients https://youtu.be/OSADBZHYzIM How Does Gabapentin Work? https://www.youtube.com/watch?v=UKL8MmgCVnY Find Us on Social Media : https://pinterest.com/susanbuck21/ https://selfhealthcures.blogspot.com https://selfhealthcures.tumblr.com Health Disclaimer: The information on this channel is only for educational purposes. It is not intended to be a substitute for informed medical advice or care.You should not use this information to diagnose ore treat any health problems.Please Consult A Doctor With Any Questions or concerns you might have regarding your or your family members Condition. Thanks. All Images Are licensed under CC: www.pixabay.com www.flickr.com www.pexels.com en.wikipedia.org commons.wikimedia.org
Просмотров: 47 Self HealthCures
New Transplant Medicine Belatacept: How It Works
 
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Christian P. Larsen, Emory University, provides a nutshell explanation of a breakthrough in transplant medicine. Background The Food and Drug Administration (FDA) has approved the drug Nulojix (belatacept) for the prevention of graft rejection after kidney transplants. Belatacept could be a less toxic alternative to calcineurin inhibitors, the drugs most transplant patients now rely on to inhibit their immune systems, but which can damage the kidneys and lead to high blood pressure and diabetes. This is the first time a new class of drugs has been developed for transplant since the 1990s. Belatacept has the potential to improve and simplify the medication regimens of kidney transplant recipients, and is also now being tested in experimental clinical trials for liver transplant and pancreatic islet transplant. Since the early 1990s, Emory surgeon-scientists Christian P. Larsen, MD, DPhil and Thomas C. Pearson, MD, DPhil have been searching for ways to promote immune tolerance of a transplanted organ. They played a leading role in discovering belatacept and driving its development, in collaboration with other investigators at Emory, including the Yerkes National Primate Research Center, and researchers at Bristol-Myers Squibb.
Просмотров: 642 Emory Healthcare
What Does Mucomyst Do?
 
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Acetylcysteine, administered orally, is indicated as an antidote to prevent or lessen hepatic injury which may occur following the ingestion of a potentially hepatotoxic quantity of acetaminophen. Only mix acetylcysteine oct 12, 2017 is a drug that breaks down mucus, the substance lubricates do not other medicines in nebulizer with medical editor john plast reviewed on rxlist 12 9 2016. Googleusercontent search. Age groups, this medicine is not expected to cause different side effects or problems in children than it does adults. Acetylcysteine solution (n acetyl l cysteine) is a of naturally occurring amino acid that used to psoriasiswhat does psoriasis rash look like? . If this does not work, it may have to be suctioned out. Side effects, dosage, uses and more healthlinedefinition of mucomyst by medical dictionary. After opening, solution for inhalation may turn light purplerefrigerate open vials and discard formulary of 2006 lists acetylcysteine (nac) as an antidote use in the levels possibly toxic range that did not develop hepatotoxicity when nac was acetadote (acetylcysteine) approved by fda. The schedule for taking acetylcysteine is located in the when to oct 17, 2016 as breaks up thick, sticky mucous, you will begin absence of warnings or other information a given drug does do not confuse mucomyst with mucinex. Review of n acetylcysteine for the treatment acetaminophen. Acetylcysteine side effects, dosage, interactions drugs common effects of acetylcysteine solution (n acetyl l cysteine uses, overdose, pregnancy wikipedia. N acetylcysteine, mucomyst (acetylcysteine) dosing, indications acetylcysteine inhalation oral side effects, medical uses (inhalation route) description and brand names medlineplus drug information. Do not use more of it and do often than your doctor ordered medscape indication specific dosing for n acetylcysteine, mucomyst (acetylcysteine), acetylcysteine after angiography; Trials we did, trials should mix with other inhaled medications unless directed by the or tell if condition does improve worsens is a mucolytic (medicine that destroys dissolves mucus). Jul 27, 2017 acetylcysteine get up to date information on side and the babies did not show any medical issues related this medication acetylcysteine, also known as n (nac), is a that used for prior pharmacokinetic studies of consider acetylation reason low bioavailability. Mucomyst 10 (acetylcysteine (inhalation)) drug side effects mucomyst uses, effects, interactions, pictures, warnings conditions that treats webmd. Acetylcysteine for acetaminophen overdose utah poison control. When taken by mouth, acetylcysteine is used to prevent liver damage from acetaminophen overdose find information about which conditions mucomyst commonly treatwhat does solution treat? Respiratory system a mucolytic (myoo koe lit ik) drug that breaks down mucus, the substance lubricates many parts of body such as throat, and lungs. Do not use more or less of it often than prescribed by your do
Просмотров: 319 Claribel Pisano Tipz
Hair regrowth केवल 48 घंटा में start कर देता है यह नया दवा
 
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Hair regrowth केवल 48 घंटा मे start है यह नया दवा .
Просмотров: 11790 Hair Transplant & Business Idea Bipin
New Data Shows High Efficacy for Can-Fite's CF101 in Rheumatoid Arthritis and Psoriasis Patients
 
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PETACH TIKVA, Israel, Aug. 6, 2014 /PRNewswire/ -- Can-Fite BioPharma Ltd. (NYSE MKT: CANF) (CFBI.TA), a biotechnology company with a pipeline of proprietary small molecule drugs that address inflammatory and cancer diseases, announced today new data from a retrospective analysis of its autoimmune disease advanced trials that shows high efficacy of its orally bioavailable drug CF101. The retrospective study, conducted by a third party statistician group, analyzed the correlation between response to CF101 and patients' body mass index (BMI) in the Phase II/III Psoriasis interim results as well as the recently completed Phase II Rheumatoid Arthritis trial. The data shows a significant increase in the response to CF101 in patients with a BMI of over 25 in both studies. These findings corroborate the efficacy seen with other FDA approved drugs such as Cyclosporine A which was more effective in patients with high BMI. The company believes these findings will enable it to optimize the design of its forthcoming Phase III studies. "These new findings are further evidence of CF101's high efficacy, while the drug continues to show excellent safety in patients. We believe the data will be very important to the design of our forthcoming Phase III trials because these findings help us to achieve the maximum potential of the drug in the treatment of inflammatory conditions," stated Can-Fite CEO Pnina Fishman. Can-Fite's Phase II/III Psoriasis trial is ongoing with data expected to be released in the first quarter of 2015. The Psoriasis therapeutic market was worth $3.6 billion in 2010 and is forecast to grow to $6.7 billion by 2018, according to Global Data. The market is dominated by biological drugs that are primarily administered via intravenous injection (IV) and have potential side effects. The global Rheumatoid Arthritis drug market is expected to generate revenues of $38.5 billion in 2017, according to Visiongain. About Can-Fite BioPharma Ltd. Can-Fite BioPharma Ltd. (NYSE MKT: CANF) (CFBI.TA) is an advanced clinical stage drug development company with a platform technology that is designed to address multi-billion dollar markets in the treatment of cancer and inflammatory diseases. The Company's CF101 is in Phase II/III trials for the treatment of psoriasis and the Company is preparing for a Phase III CF101 trial for rheumatoid arthritis. Can-Fite's liver cancer drug CF102 is commencing Phase II trials and has been granted Orphan Drug Designation by the U.S. Food and Drug Administration. CF102 has also shown proof of concept to potentially treat other cancers including colon, prostate, and melanoma. These drugs have an excellent safety profile with experience in over 1,200 patients in clinical studies to date. For more information please visit: www.can-fite.com
Просмотров: 122 CorporateProfile
Paul Stamets at TEDMED 2011
 
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TEDTalks favorite Paul Stamets gave an emotional talk about new medical uses for mushrooms — including a variety that, he says, helped treat his mother’s cancer. Stamets spoke about powerful medical uses for mushrooms and their extracts, from anti-tuberculosis effects (Agarikon) to Cordyceps, a treasure trove of potential medicines, such as cyclosporine, which prevents organ rejection in transplant patients, and the recently FDA-approved drug Gilenya, from Novartis, for treating multiple sclerosis (MS). He can even use mushroom compounds to steer the migration of insects across the landscapes and control diseases carried by insects and animals. The most heartfelt moment of his talk, though, was when he brought his mother to the stage and told how he was able to help her to go from stage 4 breast cancer to tumor-free. To Know More: Email:vasupalscreation@gmail.com,vcoffice27@gmail.com Call Us:+91-44-42874048
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Humira side effects
 
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Humira side effects
Просмотров: 786 Jessica Taylor
Azithromycin Nursing Considerations, Side Effects, and Mechanism of Action Pharmacology for Nurses
 
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Grab our free cheatsheet covering the 50 most commonly prescribed medications right here: http://www.NRSNG.com/50meds View the blog post here: https://www.nrsng.com/azithromycin-zithromax/ Listen to all the episodes at: https://www.nrsng.com/medmaster-podcast/ Azithromycin Generic Name: azithromycin Trade Name: Zithromax Indication: URI, chronic bronchitis, lower respiratory infections, otitis media, skin infections, various STIs, prevention of bacterial endocarditis, treatment of cystic fibrosis Action: inhibits bacterial protein synthesis Therapeutic Class: agents for atypical mycobacterium, anti-infectives Pharmacologic Class: Macrolide Nursing Considerations:  may lead to pseudomembranous colitis, pain, diarrhea, nausea, Stevens-Johnson syndrome, angioedema  may increase risks for warfarin toxicity  monitor patient for signs of anaphylaxis  instruct patient to notify physician for diarrhea, or blood or pus in stool  instruct patient to take medication exactly as prescribed
Просмотров: 11115 NRSNG
The Full Drug Monitoring Workflow
 
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http://www.thermoscientific.com/diagnostics Drug monitoring expert Kathy Ruzich discusses the full Thermo Scientific drug monitoring and quality control workflow solution. From collection to confirmation, we offer solutions for drugs of abuse, therapeutic drugs, or even immunosuppressent drugs. Drug monitoring- drugs of abuse, therapeutic drugs, or even immunosuppressent drugs. We have devices for the collection, the instrumentation (Thermo Scientific Indiko and Indiko Plus) for analysis, as well as the reagents. The Thermo Scientific QMS Everolimus Assay Kit rounds out our menu of immunoassays for immunosuppressant drugs including cyclosporine, tacrolimus, and mycophenolic acid. To learn more, click here: http://www.thermoscientific.com/diagnostics
Просмотров: 743 Thermo Scientific
Remembering Dr. Thomas Starzl, Robert Osborne
 
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The Father of Transplantation THE TRANSPLANT DOCTOR FROM PITTSBURGH, THE HOLLYWOOD MOVIE HOST Dr. Thomas Starzl was the country’s most renowned transplant surgeon. He not only pioneered liver transplantation, he was responsible for developing the anti-rejection drugs that allowed transplantation to succeed. His work made the University of Pittsburgh Medical Center one of the top centers for transplantation in the world. Robert Osborne was the genteel host of Turner Classic Movies. Since 1994 he hosted primetime movies on the network in an informed and urbane style. He also wrote several books on movies and the Academy Awards. Thomas Earl Starzl (March 11, 1926 – March 4, 2017) was an American physician, researcher, and expert on organ transplants. He performed the first human liver transplants, and has often been referred to as "the father of modern transplantation He attended Westminster College in Fulton, Missouri, where he earned a Bachelor of Science degree in biology. Starzl attended Northwestern University Medical School in Chicago, where in 1950 he received a Master of Science degree in anatomy and in 1952 earned both a Ph.D. in neurophysiology and an M.D. with distinction.[3] While attending medical school, he established a long friendship with Professor Loyal Davis, MD a neurosurgeon.[2] Starzl spent an extra year at medical school, using the additional time to complete a doctorate in neurophysiology, in 1952. He wrote a seminal paper describing a technique to record the electrical responses of deep brain structures to sensory stimuli such as a flash of light or a loud sound. The paper is highly cited.[citation neede After obtaining his medical degree, Starzl trained in surgery at Johns Hopkins Hospital in Baltimore and Jackson Memorial Hospital in Miami. At both places, he conducted lab and animal research, showing a keen interest in liver biology Starzl's most notable accomplishments include: Performing the first human liver transplant in 1963, and the first successful human liver transplant in 1967, both at the University of Colorado Health Sciences Center.[5] Establishing the clinical utility of ciclosporin[6] (cyclosporine) in 1982, and tacrolimus in 1991, both leading to FDA approval; Development of multiple technical advances in organ preservation, procurement and transplant; Delineating the indications and limitations of abdominal organ transplantation; Defining the underlying basis for organ transplantation as a treatment of inherited metabolic diseases (thus providing the rationale for current-day gene therapy efforts); Recognizing the causative role of immunosuppression in the development of post-transplant lymphoproliferative disease and other opportunistic infections and the utility of reversing the immunosuppressed state as the principal treatment; Performing the first simultaneous heart and liver transplant on six-year-old Stormie Jones in 1984;[7] Proposing microchimerism in organ transplant tolerance.[citation needed Robert Jolin Osborne (/ˈɒzbɔːrn/; May 3, 1932 – March 6, 2017) was an American actor, film historian, television presenter, and author best known as the primary host for the cable channel Turner Classic Movies (TCM). Prior to TCM, Osborne had been a host on The Movie Channel,[1] and, earlier, a columnist for The Hollywood Reporter. Osborne also wrote the official history of the Academy Awards, originally published in 1988, and most recently revised in 2013 Osborne began his career working as a contract actor for Desi Arnaz and Lucille Ball's Desilu Studios.[4] There, Osborne became part of Lucille Ball's Desilu Workshop,[6] in which Ball worked with and nurtured such young performers as Osborne and actress-singer Carole Cook.
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Psoriasis NYC - (212)  644-6454 -  Best Psoriasis Doctor NYC - Best Psoriasis Doctor NYC
 
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http://www.psoriasisnyc.org/ (212) 644-6454 Medications Medications applied to the skin or taken by mouth are usually used to treat psoriasis. For moderate or severe cases, topical and oral medications may be combined with exposure to sunlight or ultraviolet (UV) light. In rare cases, medications may be injected into a psoriasis sore or patch. Softening and removing psoriasis crusts and scale can help creams and other skin products be absorbed into the skin. Psoriasis crusts can be removed by gently rubbing cream into the crusts to soften them and then carefully peeling the crusted patches off. However, this should be done with great care so that the skin is not irritated. Scalp and nail psoriasis can be difficult to treat. Both conditions are more likely to improve with oral medication. Treatment for the scalp often includes tar shampoos, corticosteroid solutions, or zinc and selenium sulfide shampoos. If you are taking topical or oral medications for psoriasis, you will need regular follow-up visits with your doctor to check for possible side effects or skin cancer. You may take one medication for a while, then switch to another to reduce the chance that a serious side effect will occur. Occlusion The occlusion treatment method uses moisturizers or medicated creams or gels applied to the skin. After the products are applied, the skin is then wrapped with tape, material, or plastic. Occlusion keeps the area moist and can increase the effectiveness of medicated creams. Steroid cream may be used with the occlusion treatment method for small areas, but not for more than a few days. 5 Occlusion of large areas may cause side effects such as thinning of the skin. Medication Choices Topical medications to treat psoriasis include: Corticosteroids. Corticosteroids are the most common treatment for psoriasis. 10 Calcipotriene, which contains vitamin D3. Retinoids, including tazarotene and acitretin. Anthralin and tars. The use of anthralin and tars has decreased recently, replaced by other medications such as calcipotriene and tazarotene. 5 Occlusion The occlusion treatment method uses moisturizers or medicated creams or gels applied to the skin. After the products are applied, the skin is then wrapped with tape, material, or plastic. Occlusion keeps the area moist and can increase the effectiveness of medicated creams. Steroid cream may be used with the occlusion treatment method for small areas, but not for more than a few days. 5 Occlusion of large areas may cause side effects such as thinning of the skin. Medication Choices Topical medications to treat psoriasis include: Corticosteroids. Corticosteroids are the most common treatment for psoriasis. 10 Calcipotriene, which contains vitamin D3. Retinoids, including tazarotene and acitretin. Anthralin and tars. The use of anthralin and tars has decreased recently, replaced by other medications such as calcipotriene and tazarotene. 5 Zinc pyrithione. Zinc pyrithione (for example, Derma-Cap) is a new product available without a prescription that comes in spray, soap, or solution form. It is used to treat small patches of psoriasis and symptoms, including itching, redness, flaking, and scaling of the skin. It is also used to treat psoriasis of the scalp. For some people, it appears to eliminate scales and sores caused by psoriasis. Very few studies of zinc pyrithione have been completed. Oral medications to treat psoriasis include: Retinoids. Cyclosporine. Methotrexate. Newer medicines, approved by the U.S. Food and Drug Administration (FDA) for treatment of psoriasis, are available. Biologics, which must be injected, modify the immune system response that produces the symptoms of psoriasis. Early clinical trials of biologic therapies for moderate to severe psoriasis have produced promising results, but the drugs are expensive and long-term effects are not known. Alefacept (Amevive), efalizumab (Raptiva), and etanercept (Enbrel) have been approved by the FDA for treatment of moderate to severe psoriasis. Infliximab (Remicade), which is used to treat other inflammatory diseases such as rheumatoid arthritis, is beginning to be used for psoriasis with good results. 11 Etanercept, infliximab, and adalimumab (Humira) have been approved to treat psoriatic arthritis. In general, treatment for psoriasis starts with topical medications, such as corticosteroids, calcipotriene, and tazarotene. 5 These medications may be used alone or in combination. psoriasis treatment center nyc psoriasis treatment nyc psoriasis treatment centers new york psoriasis treatment in nyc nyc best dermatologist best nyc dermatologist best cosmetic dermatologist nyc nyc dermatology new york magazine top dermatologist new york magazine best cosmetic surgeon top plastic surgeon top 10 doctors top dermatologist nyc nyc top dermatologist hollywood dermatologist dermatologist to the stars best botox doctor nyc famous dermatologist celebrity dermatologist w
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Restasis ad (2010)
 
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Seems Allergan decided to change up the ad; much better, IMO.
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Voriconazole
 
25:40
Lecture on voriconazole by Professor David Denning (National Aspergillosis Centre, Manchester, UK) for LIFE Worldwide. For slides and alternative formats please visit http://life-worldwide.org/life-education-slide-sets-video-presentations-and-reading-materials
FDA warns of fake cancer meds
 
00:40
Certain medical practices are being warned... a type of drug used to treat cancer patients isn't the real deal. Elizabeth Cohen has details.
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Immune Pharmaceuticals (IMNP) Secures Up to $11 Million in New Financing
 
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SCN's Jane King sits down with Dr. Daniel Teper, CEO & Founder of Immune Pharmaceuticals Inc. (NASDAQ: IMNP ), and Analyst/Investor John McCamant of Bionvest.com, to discuss the biopharmaceutical company and its future outlook.NEW YORK, Nov. 17, 2016 /PRNewswire/ -- Immune Pharmaceuticals (NASDAQ:IMNP) (Immune) announced today that it has secured up to $11 million in new financing from a single family office that is an existing investor. The financing includes the sale of a $1 million convertible note and up to $10 million in future equity sales at prevailing market prices in increments of at least $1 million per month. Dr. Daniel Teper, Immune's CEO commented: "We appreciate the continuous commitment of our investors to support this financing of Immune, which will be dedicated to the advancement of bertilimumab clinical development. We are also implementing a strategy to unlock the value of other assets through the establishment of new, privately-funded companies which will be partially owned by Immune." Immune continues to accrue patients in two phase 2 clinical trials for bertilimumab, a first-in-class monoclonal antibody targeting eotaxin-1: an open label 10 patient trial in the treatment of bullous pemphigoid, an orphan auto-immune dermatological condition, and a double-blind, placebo-controlled, 42 patient trial in moderate-to-severe ulcerative colitis, a gastrointestinal inflammatory condition. In both conditions, a significant number of patients have elevated levels of eotaxin-1, which is also considered a biomarker of disease severity. Targeting patients with elevated eotaxin-1 offers the potential to select patients who may be more likely to respond to treatment. Additionally in 2017, Immune plans to initiate a phase 2 trial in severe atopic dermatitis, a condition where eotaxin–1 plays an important role, and to explore the role of eotaxin-1 in patients with nonalcoholic steatohepatitis (NASH). http://www.immunepharma.com/ About Immune Pharmaceuticals Inc.: Immune Pharmaceuticals Inc. (NASDAQ: IMNP) applies a personalized approach to treating and developing novel, highly targeted antibody therapeutics to improve the lives of patients with inflammatory diseases and cancer. Immune's lead product candidate, bertilimumab, is in Phase II clinical development for moderate-to-severe ulcerative colitis as well as for bullous pemphigoid, an orphan autoimmune dermatological condition. Other indications being considered for development include atopic dermatitis, Crohn's disease, severe asthma and Non-Alcoholic Steato-Hepatitis (NASH), an inflammatory liver disease. Immune recently expanded its portfolio in immuno-dermatology with topical nano-formulated cyclosporine-A for the treatment of psoriasis and atopic dermatitis. Immune's oncology pipeline includes Ceplene® which is in late stage clinical development for maintenance remission in Acute Myeloid Leukemia (AML) in combination with IL-2. Additional oncology pipeline includes Azixa® and crolibulin, Phase II clinical stage vascular disrupting agents, and novel technology platforms; bispecific antibodies and NanomAbs™. Maxim Pharmaceuticals Inc., Immune's pain and neurology subsidiary is developing AmiKet™ and AmiKet™ Nano™ for the treatment of neuropathic pain. For more information, visit Immune's website at www.immunepharma.com, the content of which is not a part of this press release.
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Dry Eyes - Complications, Course of action And Safety mea
 
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http://visionwithoutglasses.allalla.com Restasis is a prescription drugs utilised for the procedure of dry eyes. It is an an immunosuppressant eye reduce recommended via the health care provider in direction of the sufferers with continual dry eyes. Restasis can help the eyes organic energy towards develop tears via minimizing inflammation and swelling within just the eyes. Its prosperous elements is Cyclosporine Ophthalmic method. Restasis is as well applied in the direction of control the position of immunity within the system. This medicines is made use of for other health-related disorders as no stated upon the lable of the drugs. Availability Generic:- Get 0.05% Cyclosporine 3, 6 and 12ml Model:- Acquire 0.05% 0.4mL 32, 64 and 96 vials What precaution really should i choose in advance of having Restasis? There are couple critical articles yourself need to realize right before working with Restasis. Do not consider this medications if by yourself are allergic in the direction of Restasis and in the direction of its substances Cyclosporine or in direction of any other medicines. Prior to transforming towards this medications explain to your health care provider if oneself are using any other prescription, non prescription and organic medicines. If your self are having sirolimus (Rapamune), it is amazingly substantial for oneself in the direction of get treatment that this prescription drugs really should be taken following 4 hrs of Restasis. Notify your health care provider if by yourself include the condition of very low cholestrol, liver illnesses, kidney disorders and minimal amounts of magnesium within your blood just before getting Restasis. Can i just take Restasis in the course of my being pregnant? If by yourself are expecting, designing in direction of turn out to be expecting and breast feeding mom on your own are not instructed towards retain the services of Restasis without the need of informing your physician. Employ the service of of this medicine inside of expecting and breast feeding moms may possibly destruction the unborn boy or girl and nursed youngster. Do hire of Restasis could possibly trigger progress of additional tissue within just my gums? Of course employ the service of of Restasis could lead to improvement of further tissue within your gums. Deliver certain yourself brush your tooth very carefully and consistently pay a visit to towards your dentist all through the method in the direction of prevent the possibility of severe aspect impact. Considerable info more than Restasis + Individuals utilizing Restasis prescription drugs for extended interval may possibly trigger kidney and centre failure. + Do not acquire any other medications without having consulting your medical professional. + Grape fruit and juice really should be averted as a result of sufferers who are using Restasis drug. + Seek the services of of this medicines will make a individual vulnerable towards an infection. What are the facet consequences of Restasis? Retain the services of of Restasis drugs includes some preferred in direction of really serious facet implications. Some popular aspect outcomes are Improved hair enhancement and Shivering and some critical facet outcomes are opinion bewildered, pounding of the centre, strengthen or reduce within bodyweight, listening to decline, muscle mass soreness, difference inside the colour of urine, impression fatigued and very poor muscle groups. If yourself keep track of any indications of any about talked about facet penalties by yourself sdould routinely seek the advice of your medical professional or fitness treatment industry experts. Exactly where this drugs really should be retained? This medications ought to be retail outlet at place weather at 15 towards 25 amount C. This drugs should really be shop inside of dry Space absent versus warm, gentle and dampness. Observe your self should really retail outlet this medications absent towards young children obtain. Product or service really should be discarded correctly if not within just employ.
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Hydralazine
 
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This video is about Hydralazine
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Xiidra
 
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Recently approved Xiidra, a topical eye drop for the Dry Eye Syndrome, appears likely to dethrone Restasis as the treatment of choice for this common malady. Xiidra begins to work more quickly and causes fewer side effects. Unfortunately both of these drugs cost about $5000 each year and fail to eliminate the need for supplements of artificial tears.
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Dr. Anjali Bhaisin and Alli
 
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Alli is an FDA approved over the counter weight loss drug for overweight adults 18 or older. It it strongly encouraged that this drug must be taken with a low calorie and low fat diet. Diet plans can be found online and in the package. It is taken one hour before during or after a meal, with a max of 3 pills a day. There are drug interactions especially with a popular transplant drug, so speak to a healthcare provider to see if any of your drugs interact with Alli. We recommend you start with the starter pack and then continue with the refill packages. Do not use it on cyclosporine, if you have trouble absorbing food, or if you are overweight. Take a multivitamin at bedtime. Try a well balanced, reduced-calorie, low fat diet before starting Alli. Speak to a doctor if you have had gallbladder problems, kidney stones, and pancreatitis. Stop or ask a doctor if you have severe or continuous abdominal pain occurs. In studies, most people lost 5 to 10 pounds over 6 months. Disclaimer: Any counseling is free general information that I have obtained over my education and research. I am not responsible for any harm someone may bring onto themselves or to others. If you have any questions please refer to a healthcare professional. Like, comment and tag someone you think may benefit from this video. #GetCounseled #Pharmacists #Pharmacy #L4L #Weightloss #Fat #Health #Wellness #Overweight #Obese #Doctors #Nurses #Summer #Skinny #OvertheCounter #Bikini #Gym #Fitness [Reference: Alli [package insert]. Moon Township, PA: GSK; 2015]
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London Scientists Found New Effective Medicine For Hair Regrowth - WAY 316606
 
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Xiidra Commercial (2018)
 
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#XLVI = 46 About Lifitegrast: Its used to treat the signs and symptoms of dry eye disease. Lifitegrast is in a class of medications called lymphocyte function-associated antigen-1 (LFA-1) antagonist. Lifitegrast works by reducing the swelling in the eye tissues. I DO NOT OWN THIS. ALL RIGHTS TO SHIRE.
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Restasis Eye Drops - Coupon Info, Side Effects, Cost, Reviews, and Dosage
 
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Drs. Travis and Jenna Zigler go over everything you need to know about Restasis. You can also read more by clicking here: https://eyelovethesun.com/pages/restasis-eye-drops
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Restasis by Allergan: For Invividuals Suffering with Dry Eyes
 
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Restasis by Allegan: For individuals suffering with dry eyes. This new revolutionary eye drop by Allergan is medically proven to significantly reduce, if not eliminate the common symptoms of dry eye syndrome: dryness, irritation, burning, variable vision, blur and glare and foreign body sensation. This twice a day eye drop is effective in reducing the inflammatory component of this common eye complaint, thereby improving normal tear production. Please consult your eye care physician to determine if you would benefit for a Free Trial on Restasis or visit us online at www.Restasis44.com. Restasis is contraindicated in patients with Herpes Eye Disease. Restasis is a product of Allergan Pharmaceutical uploaded to Google Video as a public service by The Fladen Eye and Lasik Center. Allergan
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Immune Pharmaceuticals, Inc. @ 2nd IOBDLI Forum
 
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Immune Pharmaceuticals Inc. (NASDAQ: IMNP) applies a personalized approach to treating and developing novel, highly targeted antibody therapeutics to improve the lives of patients with inflammatory diseases and cancer. Immune's lead product candidate, bertilimumab, is in Phase II clinical development for moderate-to-severe ulcerative colitis as well as for bullous pemphigoid, an orphan autoimmune dermatological condition. Other indications being considered for development include atopic dermatitis, Crohn's disease, severe asthma and NASH (an inflammatory liver disease). Immune recently expanded its portfolio in immuno-dermatology with topical nano-formulated cyclosporine-A for the treatment of psoriasis and atopic dermatitis. Immune's oncology pipeline includes Ceplene/IL-2 approved in Europe and Israel for maintenance remission in AML, Azixa and crolibulin, Phase II-ready vascular disrupting agents, and novel technology platforms; bispecific antibodies and targeted nanotherapeutics, NanomAbs. Immune's additional pipeline includes AmiKet Nano™, a late clinical stage drug candidate for the treatment of neuropathic pain. For more information, visit Immune's website at www.immunepharmaceuticals.com
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Drug metabolism made simple
 
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The primary site of drug metabolism is the liver, the organ that plays a major role in metabolism, digestion, detoxification, and elimination of substances from the body. Enzymes in the liver are responsible for chemically changing drug components into substances known as metabolites. Metabolites are then bound to other substances for excretion through the lungs, or bodily fluids such as saliva, sweat, breast milk, and urine, or through reabsorption by the intestines. The primary mode of excretion is through the kidneys.The family of liver isoenzymes known as cytochrome P-450 are crucial to drug metabolism. These enzymes (labeled CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4) have a catabolic action on substances, breaking them down into metabolites. Consequently, they also act to lower the concentration of medication in the bloodstream. Drug interactions can occur when one drug inhibits or induces a P-450 that acts on another drug. An example is nicotine, a drug contained in tobacco, and known to induce P-450s. Individuals with liver disease (e.g., cirrhosis) may also have insufficient levels of P-450 enzymes. As a result, the concentration of drugs metabolized by these enzymes (e.g., amprenavir and other protease inhibitors) remains high and can build up to toxic levels in the bloodstream. In addition, certain medications and foods, such as grapefruit juice, can inactivate or lessen the metabolic activity of P-450s. Changing the drug dosage can alleviate the problem in some cases. The metabolic rate can vary significantly from person to person, and drug dosages that work quickly and effectively in one individual may not work well for another.Foods and beverages that may interact with drugs include: Grapefruit juice. Grapefruit juice inhibits the metabolism of many medications, including cyclosporine, felodipine, nifedipine, nitrendipine, nisoldipine, carbamazepine, triazolam, and midazolam. Foods and beverages with tyramines. Red wine, malted beers, smoked foods (e.g., fish and meats), dried fruits, and aged cheeses may contain tyramines, and can cause a severe and dangerous elevation in blood pressure when taken with MAOI inhibitors (a class of antidepressants). Dairy products. Milk, cream, and other dairy products containing calcium can prevention the absorption of antibiotics such as tetracycline, doxycycline, and ciprofloxacin when they are taken with the drug. In addition, whole milk with vitamin D can cause milk-alkali syndrome in patients taking aluminum hydroxide antacids. Caffeinated beverages. The caffeine contained in coffee and colas can influence drug metabolism. This list is not all-inclusive and individuals should always let their doctor and pharmacist know when they are taking other medications, herbal remedies, or dietary supplements. Anyone who experiences a serious reaction to a drug that is not consistent with its product labeling should report the event to their doctor and/or the MedWatch adverse event reporting system of the United States Food and Drug Administration (FDA).Drug interactions can be difficult to detect. In some cases, adverse reactions may closely resemble the symptoms of the disease or condition the medication was prescribed to treat. Patients who take a number of medications or self-treat with over-the-counter drugs and/or herbal remedies may not be able to determine which drug actually triggered the interaction. A 2001 study by University of Florida researchers found that less than half of the women participating disclosed their use of herbal therapies to their healthcare providers. In cases where a serious drug or herb interaction occurs, withholding this information can delay diagnosis and put the patient at increased risk.Key terms Catabolism — A process of metabolism that breaks down complex substances into simple ones. Cirrhosis — Liver disease characterized by the widespread disruption of the normal liver structure and function. CNS depressant — Anything that depresses, or slows, the sympathetic impulses of the central nervous system (i.e., respiratory rate, heart rate). Drug interaction — A chemical or physiological reaction that can occur when two different drugs are taken together. Enzymes — Organic substances (proteins) composed of amino acids that trigger and regulate chemical reactions in the body. There are over 700 identified human enzymes. Liver — A solid organ located on the right in the upper abdomen. It plays a major role in metabolism, digestion, detoxification, and elimination of substances from the body. Metabolism — The sum of all the physical and chemical processes occurring in the body to organize and maintain life. Metabolites — Substances produced by metabolism or by a metabolic process. Please like share and Subscribe my YouTube channel and don't forget to Click bell Icon for latest update. Thanks
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