**EDIT: More medications than just the 2 I listed can be used to treat hospital-associated MRSA. I was mistaken. However, there are still many more options for community-acquired than hospital-acquired.** Explanation of the concept surrounding the double disk diffusion assay used for clindamycin-sensitive, erythromycin-resistant MRSA.
Просмотров: 286 Catherine Ingram
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Просмотров: 170286 Tomiwa Rodia
Developed and produced by http://www.MechanismsinMedicine.com Animation Description: The DNA is shown as a circular double strand within the bacterial cell. Like the DNA of all living organisms, it contains the unique genetic code for all of the proteins required for bacterial survival. These include the proteins required for reproduction, growth, repair and regulation of metabolism. It also codes for the 3 kinds of RNA that are essential for carrying out protein synthesis. These are known as ribosomal RNA (rRNA), messenger RNA (mRNA) and transfer RNA (tRNA). In order for the bacteria to begin protein synthesis, the double-stranded DNA molecule must first unwind and separate in the region which codes for the specific protein that is to be made. Only one strand of the DNA serves as the template for this process known as transcription. Transcription results in the formation of messenger RNA (mRNA) which is a mirror copy of the DNA segment. Once the strand of mRNA is complete, it will detach from the DNA template and in turn become attached to ribosomes. Bacterial ribosomes are made of a small (30S) and a large (50S) subunit. After the 2 subunits join together around the strand of mRNA, synthesis of the polypeptide chain begins. This step involves the aligning of transfer RNA (tRNA) molecules in sequence along the mRNA. Each tRNA carries a unique amino acid (determined by the sequence of the tRNA) which, when aligned along the mRNA and ribosome, join together to form the polypeptide chain. This step is known as translation. The ribosome will continue to add amino acids to the growing polypeptide chain until it reaches a point along the mRNA that signals it to stop. At this point it releases the finished protein molecule. Macrolide antibiotics such as erythromycin, act as inhibitors of protein synthesis by attaching to the 50S ribosomal subunit. By so doing, they block the ability of the ribosome to synthesize the polypeptide chain. By inhibiting protein synthesis, macrolides are considered bacteriostatic antibiotics. However, at higher concentrations and with lower bacterial density or during rapid bacterial growth, macrolides may be bactericidal. Changes or modifications to the 50S ribosomal subunit (i.e. the target binding site for macrolide antibiotics) will confer resistance to macrolides and sometimes other classes of antibiotics. This type of resistance may be of a high level. This mechanism of resistance is mediated by the erm (erythromycin ribosome methlylation) gene which is found on plasmids or transposons (i.e. small genetic elements which are capable of moving from one bacterium to another and integrating into the host chromosomal DNA). Copies of the erm gene are transported to other bacteria via plasmids or transposons through "pili-like" channels. The erm gene is incorporated into the new bacterial genome. During the process of protein synthesis, this bacterium will transcribe and translate the genetic code of the erm gene resulting in the production of a protein enzyme capable of methylating the 50S ribosomal subunit at a specific position. This altered 50S subunit results in decreased binding affinity for macrolides and other antibiotics such as lincosamides (e.g. clindamycin) and streptogramin type B. This pattern of resistance is referred to as the MLS phenotype. Because the macrolide antibiotic is unable to bind to the 50S ribosomal subunit, it is unable to inhibit protein synthesis and thus the bacteria itself is not harmed, continuing to produce polypeptide chains of amino acids. A second mechanism of bacterial resistance to macrolide antibiotics is mediated by efflux pumps. These efflux pumps are encoded by the mef(A) gene which is a transposable element. Because they confer resistance to only macrolides and not lincosamides or streptogramin B they are referred to as the M phenotype. The efflux pumps are energy-dependent and for S. pneuomoniae result in moderate levels of resistance. These pumps traverse the cell membrane of the bacteria and function to "pump out" the macrolide antibiotic after it has entered the bacterium. It should be noted that for other bacteria such as Staphylococcus aureus for example, a different efflux system which is plasmid-mediated and encoded by the msr(A) gene results in macrolide resistance as well as lincosamide and streptogramin resistance in some cases. Despite the presence of these efflux pumps, macrolide antibiotics continue to enter the bacteria. However, once inside the cytoplasm of the bacteria, these efflux pumps actively remove the macrolide antibiotics before they have a chance to reach their target, the 50S ribosomal subunit and bacterial protein synthesis is unaffected.
Просмотров: 218785 Mechanisms in Medicine
Grab our free cheatsheet covering the 50 most commonly prescribed medications right here: http://NRSNG.com/50meds Listen to all the episodes at: https://www.nrsng.com/medmaster-podcast/ View the blog post here: https://www.nrsng.com/erythromycin/ Erythromycin Generic Name: erythromycin Trade Name: E-Mycin Indication: useful in place of penicillin when patient cannot take penicillin, upper and lower respiratory tract infections, otitis media, skin infections, pertussis, syphilis, rheumatic fever Action: Bacteriostatic: suppresses bacterial protein synthesis Therapeutic Class: anti-infective Pharmacologic Class: macrolide Nursing Considerations: Causes QT prolongation, ventricular arrhythmias diarrhea asses infection monitor liver function tests instruct patient to finish medication dosage even if they are feeling better medication should not be shared
Просмотров: 12197 NRSNG
Grab our free cheatsheet covering the 50 most commonly prescribed medications right here: http://NRSNG.com/50meds Listen to all the episodes at: https://www.nrsng.com/medmaster-podcast/ View the blog post here: https://www.nrsng.com/clindamycin-cleocin/ Clindamycin Generic Name: clindamycin Trade Name: Cleocin Indication skin infections, respiratory tract infections, septicemia, intra-abdominal infections, osteomyelitis Action: bacteriostatic: inhibits protein synthesis Therapeutic Class: Anti-infectives Pharmacologic Class: none Nursing Considerations: arrythmias, pseudomembranous colitis, diarrhea, phlebitis monitor bowel function assess for infection, obtain cultures prior to therapy monitor liver function tests monitor CBC
Просмотров: 11488 NRSNG
Learn Macrolides faster with the Picmonic Learning System! TRY PICMONIC FOR FREE ► https://www.picmonic.com/?utm_source=youtube&utm_medium=social&utm_term=1481129673&utm_content=video_link&utm_campaign=youtubenursingpicmonicwalkthroughs_2016 ————————————————— Picmonic turns the information you need to know in medical and nursing school into unforgettable images and stories that are scientifically proven to increase memory retention! Join over 125,000 medical and nursing students using Picmonic’s Visual Learning Community to study and learn more effectively in less time. Picmonic is research proven to increase test scores by 50% and long-term memory retention by 331%. Picmonic for Medicine has you covered for USMLE Step 1 and Step 2 CK, with subject including Pathology, Pharmacology, Microbiology, Biochemistry, Psychiatry, Anatomy, Physiology, Epidemiology, and more! Picmonic for Nursing has you covered for your classes and the NCLEX® with subjects including Fundamentals, Pharmacology, Med-Surg, Anatomy, Physiology, Pediatrics, Obstetrics, Psychiatric, and more! ————————————————— LET’S CONNECT! General Facebook ► https://www.facebook.com/picmonic Nursing Facebook ► https://www.facebook.com/picmonicfornursing Twitter ► https://twitter.com/picmonic Instagram ► https://www.instagram.com/picmonic/ Pinterest ► https://www.pinterest.com/picmonic/ LinkedIn ► https://www.linkedin.com/company/2703135 Google+ ► https://plus.google.com/+Picmonic/posts —————————————————
Просмотров: 17114 PicmonicVideo
This antibiotic tutorial explains the mode of action of macrolide antibiotics. It also explains the use and side effects of macrolides in antibacterial treatment. For more information, log on to- http://shomusbiology.weebly.com/ Download the study materials here- http://shomusbiology.weebly.com/bio-materials.html
Просмотров: 16414 Shomu's Biology
This is my experience with my prescription for acne. This is by prescription only. Ask your doctor about it and if it is right for you. https://medlineplus.gov/druginfo/meds/a603024.html Can you help with my upcoming surgery? gf.me/u/jjtctx
Просмотров: 2752 Life Help Express
5/15 10pm - A potent "go-to" antibiotic that doctors prescribe often could be destroying more than your infection, CALL7 Investigators have discovered.
Просмотров: 13652 Denver7 – The Denver Channel
Pregnancy, while amazing, is also quite challenging. And the last thing you need is either the worsening of your acne, or a new pregnancy acne breakout. However, if it does occur, there are ways to treat acne during pregnancy. In this episode of DermTV, Dr. Schultz tells you how to treat acne during pregnancy. Subscribe to DermTV: http://www.youtube.com/dermtvdotcom http://DermTV.com Connect with DermTV: http://www.facebook.com/dermtv http://www.twitter.com/dermtv The Progressive Peel: http://brx.co/YVhxwI BeautyRx: http://www.beautyrx.com [TRANSCRIPT] Pregnancy is a wonderful but challenging time. And acne can make it even more challenging. You may have entered your pregnancy with existing acne breakouts. Or even more frustratingly, hormones may cause breakouts to re-occur or worsen. But the good news is that the same three avenues of acne treatment used outside of pregnancy – topical treatments, oral treatments, and facial acne cleanings – are still applicable… with some caveats. Today you’ll find out what you can do and what you can’t do for your acne while you’re pregnant. If you have acne when you get pregnant, there’s a 50/50 chance it will get better, just from being pregnant. There’s also a 50/50 chance that due to your altered hormonal state, it will get even worse. And, if you don’t have acne, pregnancy may even cause it. Unfortunately, there’s no way to predict who the lucky first group will be. However, if you’re in the second two groups, and you’re more apt to be in these groups if you often have a flare up at the start of your menstrual cycle, here are some tips to help you control your pregnancy acne. Topical treatments that are generally considered safe in pregnancy are acne face washes and toners, as well as many spot treatments such as benzoyl peroxide and salicylic acid products. I recommend at home glycolic products throughout pregnancy as a whole face treatment to help prevent breakouts as well as a spot treatment for specific blemishes. Topical antibiotics include Erythromycin and Clindamycin. The super cautious may not feel comfortable using anything but cleansers and toners in the first trimester, and of course you should use whatever you’re most comfortable with. And I can't stress enough, all retinoids must be avoided. In terms of acne cleanings… Cleaning out clogged pores and blemishes is also very helpful and need not be avoided in pregnancy. Whether done by a facialist or in a dermatology office, it results in faster resolution of pimples. Professional-strength glycolic treatments help to both prevent new breakouts and treat existing ones. As with most courses of acne treatment, it’s recommended to start with the simplest solutions and step up the treatment only if needed. So if you are not responding to the topicals or acne cleanings I mentioned, oral medications may be warranted… Again, depending on your tolerance for taking any pills during pregnancy that aren’t vital to your health and in consultation with your doctors. Cephalexin and Erythromycin are commonly prescribed in the last two trimesters, but again consult with your doctors. Pregnancy is a wonderful but challenging time. However, I can now say that being able to treat your breakouts with these techniques hopefully will make it just a little less challenging! [ABOUT DERMTV] Everyone can have beautiful, healthy, and younger looking skin, and DermTV, the Internet's daily skincare video show, will demonstrate how by revealing expert tips and techniques and by providing real solutions for real skincare issues. Skincare (whether cosmetic or medical) previously required a trip to your dermatologist or a shopping spree at the pharmacy. And that's if you have a trusted nearby dermatologist or a local informed pharmacy. But not anymore. We at DermTV are committed to making best-in-class dermatology and skincare guidance accessible to everyone, anytime, at your computer. Every weekday, our host, Dr. Neal Schultz, one of New York's most trusted and respected dermatologists, teaches skincare's most timely and timeless issues. Topics include: the best at home techniques and new technology for facial rejuvenation, preventing and fixing sun damage from wrinkles to skin cancer, breaking news in dermatology, general skincare topics, and more.
Просмотров: 18936 dermTVdotcom
http://www.cysticacnehelp.com/antibiotics-for-acne/ Antibiotics are the most commonly used method for treating acne. There are different antibiotics used to treat acne. They all work in more or less the same way. Acne antibiotics can either be used orally or applied on the skin. Although they can help reduce and clear acne breakouts, these antibiotics have their associated side effect. Oral antibiotics for acne There are different types of oral antibiotics prescribed for the treatment of acne. The most common of these include the following. Tetracycline is one of the commonly prescribed acne treatments. For effectiveness, the patient has to take the medication on an empty stomach. Taking the medication with meals reduces its effectiveness. It has a derivative, minocycline which is commonly prescribed for treatment of pustular acne. Doxycycline is an acne treatment antibiotic commonly prescribed for patients whose acne conditions don't respond to treatment with tetracycline or minocycline. It should be taken with food. Two other antibiotics for acne: Erythromycin and Clindamycin Possible side effects of oral antibiotics for acne Nausea and vomiting Candida vaginal yeast infection in women Interaction with birth control pills lessening their effectiveness Increased skin sensitivity to the sun Allergic reactions to the medication Many acne sufferers have found the antibiotics to be quite effective in combating acne breakouts. However, effectiveness comes down to the type of antibiotics for acne used and the individual's condition. A study showed that the acne causing bacteria is becoming resistant to some of the antibiotics making them less effective for treatment. Finding the most effective antibiotics for acne to treat your breakouts can be a costly affair. The problem is that not all antibiotics available guarantee great results. If you want effective acne treatment methods which guarantee results despite your acne condition, I have compiled a short report detailing 5 easy steps to get rid of acne. The five steps involved in the report don't have any side effects and are cost effective. Click on the link above, you'll find more articles about antibiotics for acne treatment and on the site http://www.cysticacnehelp.com you'll find a collection of the best articles from the net about anything concerning acne. Subscribe to the channel : https://www.youtube.com/user/cysticacnehelp Video : http://youtu.be/kv2fCDMHpv4 article source : http://www.articlesbase.com/acne-articles/antibiotics-for-acne-care-5566552.html
Просмотров: 150014 cysticacnehelp
In this video , I have discussed about the Macrolide Antibiotics , their uses and ADVERSE EFFECTS . The Mechanism of Action of Macrolide Antibiotics have been explained as to how they bind to the 50 S subunit of bacterial ribosome and inhibit Protein Synthesis .
Просмотров: 2605 Dr Anshuman Tripathi
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Просмотров: 56662 Meka Leah
This antibiotic video tutorial explains the mode of action of 50s ribosome inhibitor antibiotics. These antibiotics are among protein biosynthesis inhibitors. For more information, log on to- http://shomusbiology.weebly.com/ Download the study materials here- http://shomusbiology.weebly.com/bio-materials.html
Просмотров: 21396 Shomu's Biology
FREE Audiobook to first time Audible users https://www.amazon.com/Memorizing-Pharmacology-A-Relaxed-Approach/dp/B01FSR7XZO/ Pronunciation flashcards for the medications in the print, e-book, and pharmacology audiobook Memorizing Pharmacology: A Relaxed Approach. More difficult medication names will have two pronunciation videos, a flashcard short version and an extended version breaking the pronunciation down syllable by syllable.
Просмотров: 14006 Tony PharmD
The D testEasy way to rememberLike ABCD Macrolide-Inducible Resistance to Clindamycin By PARESH PATEL B.Pharm, MS CLS(ASCP) For serious infections such as sepsis, pneumonia, or other invasive S. aureus infections taking the small causing bad effect to patients. Usually done during erythromycin resistant and clindamycin sensitive. How you remember which one induce and which one resistance? Which macrolide involve? Erythomycin,azithromycin,clindamycin etc. People say so many things to remember? Very hard? I said its easy..!! You know ABCDE? D= D-test C=Clindamycin E= Erythromycin C come first so induce first Hopefully Its help You.. Like it then share it other friends. Subscribes for more videos
Просмотров: 3168 InFomGuru
5 Antibiotics Declared Safe At All Stages of Pregnancy.... ►►https://youtu.be/fCziSMPMjdM Once that plus sign appears on your pregnancy test, you know your body is in for a lot of changes. But what you probably didn't know is that those changes can mean more infections -- and more antibiotics. The most recent National Birth Defects Prevention Study of more than 13,000 pregnant women found that about 30 percent of women undergo at least one course of antibiotic treatment between the three months prior to conception and the end of their pregnancies, most commonly during the fourth month of pregnancy. Select antibiotic use has the potential to cause congenital abnormalities in newborns. So do you take the antibiotic and get better, or skip it and risk birth defects? Don't worry -- according to the study, it's not that black-and-white and there are safe options available. Here, we provide tips on keeping both you and your baby healthy.
Просмотров: 18966 Pregnancy To Mom
In a new world of antibiotic resistance, are acne treatments using antibiotics safe? Dermatologist Dr. Richard Thomas gives us an insightful response which may surprise you. Why are antibiotics used to treat acne? Antibiotics are not used for its primary function when used to treat acne as acne is not an infection; you can't pass on acne from one person to another. Antibiotics do suppress P. Acnes, a bacteria that is often associated with acne and proliferate around the areas that are affected. Its main function, however is in its anti-inflammatory effect. It's important to know that they act slowly. Unlike treating an infection like a strep throat, the effects are extremely slow. In acne, the expectation might be something like a 50% improvement over 12 weeks. The general philosophy for prescribing antibiotics for treating acne has changed over the decades. There is a greater awareness of antibiotic resistance. Generally antibiotics are used for shorter periods, and there is a greater use of topicals rather than antibiotics for long-term maintenance. Benzoyl peroxide or other topicals can be used in conjunction with antibiotics to treat acne. It's a matter of weighing out the benefits and drawbacks when using antibiotics to treat acne. Is it beneficial? Yes, but it's not ideal. Dr. Richard Thomas is a dermatologist that currently practices at Sidra Research and Medical Centre in Doha, Qatar. http://www.sidra.org/ What kind of content would you like to see? Do you have any questions you'd like answered by a dermatologist? We'd love to hear your feedback in the comments section! For more educational videos about dermatology and skincare, please subscribe to our YouTube Channel! https://www.youtube.com/user/skinexpertstalk For monthly newsletter on the latest skincare topics, visit us at http://dermletter.com/
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My blog :- https://driansari.blogspot.com/?m=1 About this video : In this video you can learn about antibiotic groups in hindi. Antibiotic groups ke bare me is aasan hindi/urdu video se jaaniye. Penicillin : Amoxicillin, Piperacillin, Dicloxacillin, Ampicillin, Cloxacillin. Cephalosporins : Cefixime, Cefotaxime, Ceftriaxone, Cefoperazone, Cefuroxime. Macrolides : Azithromycin, Clarithromycin, Erythromycin. Flouroquinolones : Ofloxacin, Norfloxacin, Ciprofloxacin. Tetracyclines : Doxycycline, Tetracycline. Beta - Lactams : Clavulanic acid, Sulbactum. Aminoglycosides : Neomycin, Kanamycin, Amikacin, Gentamicin, Tobramycin. Lincosamides : Clindamycin. Sulfonamides : Sulfadiazine, Sulfamethiazole, Sulfamethoxazole, Sulfisoxazole. Amphenicol : Chloramphenicol. The full name of Dr.I.Ansari is Dr.Irfan Ansari. He is a General Practitioner. He is practicing in Bokaro, jodhadih more, main road chas at Barnwaal medicals near neelam Hospital. Visiting time : 4:00pm to 6:00pm daily. Connect us on : Facebook page :-- https://mbasic.facebook.com/DrIAnsari-1980000482267049/?view_public_for=1980000482267049&_rdr *Most popular videos of this channel is here Diet for piles/fissure/fistula: https://youtu.be/zqoNpDcggF0 Medical treatment for fissure: https://youtu.be/2IJSIsMrJCo Allopathic medicine for piles/ piles ka ilaj:https://youtu.be/pafivstr-KY * Is channel ke sabse popular videos Diet for piles/fissure/fistula: https://youtu.be/zqoNpDcggF0 Medical treatment for fissure: https://youtu.be/2IJSIsMrJCo Allopathic medicine for piles/ piles ka ilaj:https://youtu.be/pafivstr-KY * This channel's main aim is to give basic knowledge of medical science to the people so that they could know about various disease that is common in india. All videos of this channel is in hindi language. We always effort that all knowledges about medical science is to give you in very easy way. We think that every people should know basic knowledge of the medical science so that they overcame from any disease soon. We always feel that many people worry about own disease but can't do any self action due to lack knowledge of medical science. But here you can get extra knowledge of medical science that is very important for your daily life. So, you should subscribe to our channel. * For subscribe to our channel : https://goo.gl/wTm3Qd * 'Dr.I.Ansari' ke You Tube channel ko subscribe karne ke liye yahan click kijiye https://goo.gl/wTm3Qd *' डॉ.आइ.अंसारी ' के यूट्यूब चैनल को सब्सक्राइब करने के लिए यहाँ क्लिक करें https://goo.gl/wTm3Qd Now every Sunday at 7:00 am a new video will be publish on this channel. Thanks for watching ! * visit our YouTube channel -- https://goo.gl/7FQGH1 *Hamara YouTube channel dekhiye -- https://goo.gl/7FQGH1 * हमारा यूट्यूब चैनल देखिए -- https://goo.gl/7FQGH1
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Reduce inflammation of acne by correctly applying benzoyl peroxide (BP) cream. Benzoyl Peroxide is both an anti-bacterial and exfoliant that works by loosening dead skin cells that are stuck within the follicle. It also releases oxygen within the follicle to kill bacteria, reducing inflammation. Because it doubles as an exfoliant and potent anti-bacterial, it’s rare that acne clears up without Benzoyl Peroxide. BP comes in strengths of 2.5%-10%, depending on the severity of acne being treated and skin sensitivity, and can be a cream, gel, cleanser, or spot treatment. BP is one of the few acne ingredients that works immediately, so you actually get a benefit from it when it’s in cleanser form. However, BP is active for up to 4 hours after applied to the skin, so leaving it on overnight in a cream or gel form is the best way to get its full benefit. It’s important to note that oil-based moisturizers stop the action of BP, so it can only be used with water based hydrators like our Hydra Gel, Hyaluronic Serum, or Vitamin C Serum. http://www.oaklandacne.com/
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Sharing my story on why I regret taking antibiotics for my cystic acne. I hope this video helps shed some light on why frequent antibiotic use is highly problematic and dangerous to our gut health, skin and immune system. DISCLAIMER: I am not a doctor or nutritionist. This post and tips are from MY own personal experience with healing acne and should NOT be substituted for nutritional or medical advice. Please consult with your physician before trying anything. You may experience different results with the advice I share and that’s ok, as we are all different and need different things. WATCH - Shopping For Skin Clearing Probiotics and Prebiotics: https://youtu.be/T875K6jEU4c ------------------------------------------------------------------------------------------------------------ THANK YOU GUYS FOR ALWAYS SHOWING ME SO MUCH LOVE. CONNECT WITH ME ON SOCIAL MEDIA Instagram - https://www.instagram.com/_katsanchez/ Twitter - https://twitter.com/_KatSanchez ------------------------------------------------------------------------------------------------------------ DO YOUR RESEARCH Leaky Gut Explained: https://bit.ly/2KOd4nV How Antibiotics Wreak Havoc on Your Gut: https://bit.ly/2uzPQPh Why Taking Antibiotics for Acne is doing more harm than good: https://bit.ly/2t7BDGb
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Pronunciation flashcards for the medications in the print, e-book, and pharmacology audiobook Memorizing Pharmacology: A Relaxed Approach. More difficult medication names will have two pronunciation videos, a flashcard short version and an extended version breaking the pronunciation down syllable by syllable.
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Dr. Ebraheim’s educational animated video describes how the antibiotic works,its mechanism of action,and all you need to know about it in a simple and easy video, with images that helps you understand more- PART 1. Antibiotics are grouped together and work on a specific part of the bacteria. 1-Some will work on cell wall as penicillin, cephalosporins and vancomycin. 2-Polymixin will work on the cell membrane. 3-Trimethoprim, sulfonamides and Bactrim will affect folic acid synthesis. 4-Antibiotics that work on nucleic acid synthesis include: a-Work on DNA gyrase: cirpofloxacin and metronidazole (flagyl) b-Work on RNA polymerase: rifampin 5-Antibiotics that work on protein synthesis: a-On 30s subunit: tetracylcline (doxycylcine) and aminoglycosides ( gentamicin) b-On 50s subunit: clindamycin, macrolides ( erythromycin) and linezolid (zynox) Become a friend on facebook: http://www.facebook.com/drebraheim Follow me on twitter: https://twitter.com/#!/DrEbraheim_UTMC Donate to the University of Toledo Foundation Department of Orthopaedic Surgery Endowed Chair Fund: https://www.utfoundation.org/foundation/home/Give_Online.aspx?sig=29
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Buy Online :- https://m.netmeds.com/prescriptions/erytop-gel-20gm You Can Connect With Me On Email : firstname.lastname@example.org Thank You For Watching If You Liked The Video Please Hit Subscribe . anmol hindi anmolhindi -------------------------------------------------------------------------- Subscribe To Our YouTube Channel : https://youtube.com/anmolhindi /+anmolhindi https://twitter.com/anmolhindi https://facebook.com/Anmol-hindi
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Dr. Ebraheim’s educational animated video describes how the antibiotic works. •Cell wall: 1.Penicillins 2.Cephalosporins 3.vancomycin Inhibit the cell wall synthesis by blocking the cross-linking. The penicillin-binding protein enzymes are involved in the cross-linking. Beta-lactams have a ring that binds to the enzyme and prevents the cell wall synthesis. When beta-lactam inhibits the cell wall synthesis, this will cause damage to the bacterial cell. If you are allergic to penicillin or cephalosporins, you may be given clindamycin or vancomycin. Vancomycin may be given if methicillin-resistant Staphylococcus aureus (MRSA) is suspected or encountered (vancomycin is essential in the treatment of MRSA). Patients allergic to clindamycin may be given Cipro. The penicillin-binding protein is involved. mecA gene allows a bacterium to be resistant to antibiotics. This is how MRSA develops. The bacteria produce an altered penicillin-binding protein that can do the cross-linking but has no affinity to Beta-lactam antibiotics. It renders the bacteria resistant to the effects of penicillin and cephalosporins. Vancomycin is used in these cases. The transformation from one bacteria to another. Plasmid. Three main mechanisms by which resistant genes can be transferred: 1.Conjugation: the bacteria may conjugate their DNA from one bacteria to the other through transformation via a sex pilus. 2.Transformation 3.Transduction There is another mechanism which produces an enzyme that will inactivate the drugs before it reaches the bacteria. This is beta-lactamase which is capable of destroying the beta-lactam antibiotics. The bata-lactam ring of the antibiotics is destroyed and will not be able to bind to the wall. •Cell membrane: polymyxin. Polymyxin will increase the cell wall permeability. •Folic acid synthesis: sulfonamides, trimethoprim. •Nucleic acid synthesis: •DNA synthesis inhibitors: 1- Fluoroquinolones: ciprofloxacin (gyrase). DNA gyrase is responsible for removing the superhelical twist so that DNA replication can proceed. The fluoroquinolones inhibit the DNA gyrase. Using cirpo may contribute to the condition of Achilles tendon rupture. 2- Metronidazole (direct effect on DNA). Bacteriocidal that creates free oxygen radicals that are metabolic bi-products which disrupt the DNA. Can be used to treat pseudomembranous colitis c.diff. RNA polymerase inhibitors: rifampin. RNA polymerase is an enzyme that produces messenger RNA. The synthesis of messenger RNA is called transcription. Messenger RNA is DNA dependant and uses it as a template. Rifampin targets and inactivates the RNA polymerase bacterial enzyme. Rifampin works against staph infection and the Mycobacterium tuberculosis (TB). Staphylococcus aureus that is phagocytosed by the macrophages causes them to become intracellular (antibiotics cannot reach). 30S: 1.tetracyclines (doxycycline): avoided in children less than 12 years (impaired growth, and teeth discoloration) may be used to treat Lyme disease. 2.aminoglycosides (gentamycin): possible problems with ears or kidneys. It is used to treat ope fractures type III. 50S: 1.Clindamycin: may cause pseudomembranous colitis (c.diff). monitor patients who are taking warfarin (Coumadin). It can wipe out the bacteria flora from the gut (intestinal bacteria secrete vitamin K). usually used if the patient is allergic to penicillins or Ancef. Clindamycin creates C/diff that is helped by antibiotics. Use cirpo if allergy to clindamycin or flagyl if c.diff is created. Clindamycin will achieve the highest concentration in bone. 2.macrolides (erythromycin): be aware of Coumadin interaction. 3.Zyvox (linezolid): used in resistant gram-positive bacteria 4.chloramphenicol: watch out for anaplastic anemia. Other points of interest •When you add antibiotics to the cement, the maximum effect occurs at 2 weeks and there will be no effect at 8 weeks. •Panton-Valentine Leukocidin (PVL) is a cytotoxin produced by Staphylococcus aureus and this toxin may cause necrotizing fasciitis or necrosis of the tissues. It is usually found in the community-acquired cases of MRSA. There will be more complex infection. More incidence of DVT and PE. Become a friend on facebook: http://www.facebook.com/drebraheim Follow me on twitter: https://twitter.com/#!/DrEbraheim_UTMC Donate to the University of Toledo Foundation Department of Orthopaedic Surgery Endowed Chair Fund: https://www.utfoundation.org/foundation/home/Give_Online.aspx?sig=29
Просмотров: 7623 nabil ebraheim
Mnemonics on Drugs acting on Ribosomal Subunits Buy AT 30 ( Drugs acting on smaller sub unit of bacterial ribosome – 30s ) A = Aminoglycosides T = Tetracycline Aminoglycosides includes Streptomycin, Gentamicin, Amikacin, Tobramycin etc. CELL at 50 ( Drugs acting on bigger sub unit of bacterial ribosome – 30s ) C= Chloramphenicol E = Erythromycin L =Linezolid L = cLindamycin Drugs acting on Ribosomal Subunits Mnemonics Pharmacology is available here - https://www.medgag.com/mnemonics/antibiotics-and-ribosome-subunits-mnemonics/
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My blog :- https://driansari.blogspot.com/?m=1 In this video you can learn about Antibiotics safe in pregnancy in hindi. Pregnancy ke douran surakshit antibiotics ke bare me is aasan hindi/urdu video se jaaniye. Safe antibiotics during pregnancy:-- Cefotaxime, Cephalexin, Cefadroxil, Cefazolin, Cefuroxime, Ceftriaxone, Cefoperazone, Cefixime, Penicillin, Ampicillin, Amoxycillin, Piperacillin, Cloxacillin, erythromycin, Clarithromycin, Clindamycin, Vancomycin, Azithromycin, Meropenem. Unsafe antibiotics during pregnancy :-- Ciprofloxacin, Norfolxacin, Ofloxacin, Moxifloxacin, Tetracycline, Doxycycline, Chloramphenicol, Amikacin, Gentamicin, Tobramycin, Aztreonam. The full name of Dr.I.Ansari is Dr.Irfan Ansari. He is a General Practitioner. He is practicing in Bokaro, jodhadih more, main road chas at Barnwaal medicals near neelam Hospital. Visiting time : 4:00pm to 6:00pm daily. Connect us on : Facebook page :-- https://goo.gl/aDATGB *Most popular videos of this channel is here Diet for piles/fissure/fistula: https://youtu.be/zqoNpDcggF0 Medical treatment for fissure: https://youtu.be/2IJSIsMrJCo Allopathic medicine for piles/ piles ka ilaj:https://youtu.be/pafivstr-KY * Is channel ke sabse popular videos Diet for piles/fissure/fistula: https://youtu.be/zqoNpDcggF0 Medical treatment for fissure: https://youtu.be/2IJSIsMrJCo Allopathic medicine for piles/ piles ka ilaj:https://youtu.be/pafivstr-KY * This channel's main aim is to give basic knowledge of medical science to the people so that they could know about various disease that is common in india. All videos of this channel is in hindi language. We always effort that all knowledges about medical science is to give you in very easy way. We think that every people should know basic knowledge of the medical science so that they overcame from any disease soon. We always feel that many people worry about own disease but can't do any self action due to lack knowledge of medical science. But here you can get extra knowledge of medical science that is very important for your daily life. So, you should subscribe to our channel. * For subscribe to our channel : https://goo.gl/wTm3Qd * 'Dr.I.Ansari' ke You Tube channel ko subscribe karne ke liye yahan click kijiye https://goo.gl/wTm3Qd *' डॉ.आइ.अंसारी ' के यूट्यूब चैनल को सब्सक्राइब करने के लिए यहाँ क्लिक करें https://goo.gl/wTm3Qd Now every Sunday at 7:00 am a new video will be publish on this channel. Thanks for watching ! * visit our YouTube channel -- https://goo.gl/7FQGH1 *Hamara YouTube channel dekhiye -- https://goo.gl/7FQGH1 * हमारा यूट्यूब चैनल देखिए -- https://goo.gl/7FQGH1
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https://www.instagram.com/drdavinlim/ Instagram- for awesome skin FOR LIFE https://www.lasersandlifts.com.au My guide to skin treatments, lasers, peels, and many more http://www.realself.com/find/Australi... More before and after pictures, and real reviews How to treat perioral dermatitis- Dermatologist Explains Perioral dermatitis or POD is also called steroid induced rosacea. This is one of the most frequently seen facial rashes by dermatologists and very easy to treat. The prognosis is excellent as it rarely recurs – providing one avoids flare factors. POD is seen more frequently in women, and in some countries up to 5% of women will develop perioral dermatitis at some time of their life. POD can also occur in children- the most frequent cause are steroids, followed by occlusive sunscreen- usually physical blocking agents. What does Perioral dermatitis look like? POD looks very much like acne, however unlike acne, it does not have whiteheads and blackheads. Perioral dermatitis is also called perioroficial dermatitis and presents as pimples, zits, red lumps and bumps called papules as well as generalized redness. This rash maybe itchy and ‘stings’ if topical creams are placed on it. Skin irritation is frequently seen in patients with POD. Perioral dermatitis as the name suggest occurs around the mouth area but spares a small portion of the surrounding lip causing a ‘halo affect’. The second most common area it involves is the nasal or nose area, followed by around the eyes. In patients who use strong steroids, it can involve the entire face- this is called ‘steroid induced rosacea.’ What causes perioral dermatitis? This question can be a complex one to answer, however your dermatologist can go in to the complexities- my job is to make this simple to understand. Make up and incorrect skin care can predispose to perioral dermatitis. This is especially so if one has occlusive creams and skin care. Skin irritation may predispose to POD. The biggest culprit by far are steroid creams, ointments, lotions, eye drops and even nasal sprays. Fluronated steroids cause most cases of POD- strong corticosteroids such as Elocon, Betnovate and Diprisone can trigger perioral dermatitis/ steroid induced dermatitis. Weak steroids such as hydrocortisone or even desowen can even trigger POD. Melasma treatments that contain steroids and HQ are frequent culprits. POD has also been reported with continued use of tacrolimus and pimicrolimus, and occlusive oils including Bio Oil. How to treat perioral dermatitis? If possible, see a dermatologist as a comprehensive treatment and prevention guide can be given. If one is using a steroid, stop it. This will result in a rebound or worsening of POD. Some dermatologist will give you a ‘step down’ regime. Most dermatologist will prescribe anti-inflammatory antibiotics such as doxycycline, tetracycline, minocycline, azrithomycin, or erythromycin. A course of 3-6 weeks is recommended. Topical creams can also be used, but they are not as effective. Topical creams such as Azaelic acid, erythromycin and clindamycin are especially indicated in pregnancy or in children. Make up should not be worn for 2-3 weeks to let your skin purge and breathe. No actives such as vitamin A- retinoids, vitamin B, C or retinol – AHAs should be used for 6 weeks. Sunscreen should be light and not heavy. Chemical peels and microdermabrasion should be avoided. Lasers have a limited role to play in the treatment of Perioral dermatitis however can be used to treat redness from steroid induced blood vessels. Cleansers should be simplified and used only twice a day. Night cream should be avoided. Moisturizers, if possible should be avoided for a few weeks. Be guided by your dermatologist as to the products you should be using. Most dermatologist will simplify your skin care routine. In complex cases patch testing maybe necessary- this is important if POD is recurrent. What is the prognosis of perioral dermatitis? Excellent! Once treated, this rash rarely recurs. If it perioral dermatitis returns, a further 4 to 6- week course of anti-inflammatory antibiotics should be taken under the supervision of your dermatologist. In most cases your general dermatologist will uncover the hidden rash such as dermatitis, or even seb derm- eczema, or an irritant that predisposed the initial rash! Dr Davin Lim authored the page on this condition for the Australasian College of Dermatologist. A guide of this condition can be found here. https://www.dermcoll.edu.au/atoz/perioral-dermatitis/ Note- I am a procedural and not a medical dermatologist, this is a review of a very common and basic condition to treat. I mainly perform complex laser, surgical and injectable therapy with fillers, Botox and peels. I do not treat rashes. Be guided by your MEDICAL dermatologist. Cheers, Dr Davin Lim. Brisbane. Australia.
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► FREE List of Pore Clogging Ingredients to Avoid: http://bit.ly/porecloggers ► SHOP acne products & kits: http://LuminosityAcne.com In this video, Carmen Popa, founder of Luminosity Acne Skincare will discuss all the mistakes people make with benzoyl peroxide and how to correct them so that the skin can clear up of acne. Make sure not to miss today's video! ***UPDATE: I've revised the moisturizer protocol and now moisturizer can be used 30 minutes after benzoyl peroxide has been applied to the skin. Using moisturizer sooner than 30 minutes may make BP less effective against acne. --------------------------------------------------------------------------------------------------- ★ Other Important Acne Videos ★ ►THE REAL CAUSE OF ACNE: https://www.youtube.com/watch?v=84Hb8xbJxL8 ►CHECKING MAKEUP FOR PORE CLOGGERS: https://www.youtube.com/watch?v=6qh35ellr6I ►DON'T SPOT TREAT ACNE!: https://www.youtube.com/watch?v=KAg69yS6sUw ►DON'T USE MAKEUP REMOVER WIPES!: https://www.youtube.com/watch?v=5IsWX7hW-YA --------------------------------------------------------------------------------------------------- ★ Where to Find Carmen★ INSTAGRAM: http://instagram.com/LuminosityAcne SNAPCHAT: LuminosityAcne WEBSITE & ACNE SHOP: http://LuminosityAcne.com --------------------------------------------------------------------------------------------------- ★ About Carmen ★ Carmen Popa is a licensed esthetician specializing in the successful treatment of teen & adult acne. She is also the founder of Luminosity Acne Skincare, Inc, located in Cary, North Carolina. Luminosity Acne Skincare was established in 2009 to help teens and adults suffering from acne achieve clear skin. Visit http://LuminosityAcne.com for more information on how you can work with Carmen to achieve clear skin. --------------------------------------------------------------------------------------------------- ★ Disclaimers ★ I am the owner of Luminosity Acne Skincare. This video is not sponsored. This Youtube channel is for informational and entertainment purposes only. This video is not intended to diagnosis, treat or provide medical advice. Information on this Youtube channel & video should not be considered as a substitute for medical advice. The statements made about specific products, treatments, or conditions throughout this video are not to diagnose, treat, cure or prevent disease. Please consult with your physician regarding any medical or health related diagnosis, condition, or treatment. Luminosity Acne Skincare Located in Cary, NC Serving the Raleigh, Durham, Chapel Hill, NC area for acne treatments for teens and adults. Raleigh NC Acne Treatment
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This video is about Microbiology Chapter 1 Part 6. We discuss Antibiotics Erythromycin and Tetracycline and how they target different Ribosome subunits --- See my website at: http://www.futuredochouse.com/ --- QUPI.com is looking for beta testers! Get limited free access to our Medical Question Bank - http://www.qupi.com/ ---
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Azithromycin popularly referred to as a Z-Pak is an antibiotic derived from erythromycin. While it treats a long list of common bacterial infections, it offers no assistance for the common cold or flu. Often incorrectly prescribed, it alters the normal bacteria in the intestine and regularly leads to abdominal upset and diarrhea. One, three and five days courses are available depending on the underlying condition.
Просмотров: 2212 wellnowdoctor
𝘛op 5 𝘖ral 𝘈ntibiotics 𝘧or 𝘈cne 𝘛reatment. 𝘈re 𝘵hey 𝘴afe 𝘢nd 𝘦ffective ? Antibiotics are the most commonly used method for treating acne. There are different antibiotics used to treat acne. They all work in more or less the same way. Acne antibiotics can either be used orally or applied on the skin. Although they can help reduce and clear acne breakouts, these antibiotics have their associated side effect. Oral antibiotics for acne There are different types of oral antibiotics prescribed for the treatment of acne. The most common of these include the following. Tetracycline is one of the commonly prescribed acne treatments. For effectiveness, the patient has to take the medication on an empty stomach. Taking the medication with meals reduces its effectiveness. It has a derivative, minocycline which is commonly prescribed for treatment of pustular acne. Doxycycline is an acne treatment antibiotic commonly prescribed for patients whose acne conditions don't respond to treatment with tetracycline or minocycline. It should be taken with food. Two other antibiotics for acne: Erythromycin and Clindamycin Possible side effects of oral antibiotics for acne Nausea and vomiting Candida vaginal yeast infection in women Interaction with birth control pills lessening their effectiveness Increased skin sensitivity to the sun Allergic reactions to the medication Many acne sufferers have found the antibiotics to be quite effective in combating acne breakouts. However, effectiveness comes down to the type of antibiotics for acne used and the individual's condition. A study showed that the acne causing bacteria is becoming resistant to some of the antibiotics making them less effective for treatment. Finding the most effective antibiotics for acne to treat your breakouts can be a costly affair. The problem is that not all antibiotics available guarantee great results. If you want effective acne treatment methods which guarantee results despite your acne condition, I have compiled a short report detailing 5 easy steps to get rid of acne. The five steps involved in the report don't have any side effects and are cost effective. Click on the link above, you'll find more articles about antibiotics for acne treatment and on the site you'll find a collection of the best articles from the net about anything concerning acne. Subscribe to the channel : Video : article source : Subscribe & More Videos: http://zipansion.com/yLVZ Thank for watching our Video, Please Like and Share #erythromycin, #dermatology, #dermatology
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// SORRY FOR MY COMPUTER'S LOUD BREATHING I HOPE U CAN HEAR ME OKAY // over-the-counter products ________________________ - burt's bees soap bark & chamomile deep cleansing cream - burt's bees daily moisturizing cream for sensitive skin - olay professional pro-x advanced cleansing system (aka spinny brush thing) - roc retinol correxion eye cream clean & clear advantage acne spot treatment prescribed products ________________________ - clindamycin phosphate gel usp, 1% - tretinoin cream, 0.05% (wow i pronounced that one wrong) HOPE UR SKIN IS HAPPY AND UR HAPPY AND HAVE A NICE DAY!! ♥
Просмотров: 18450 avery vernon