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Biologics for Rheumatoid Arthritis: Precision Therapy to Tame RA’s Fire
 
05:26
For many, there is no avoiding the painful and often disfiguring symptoms of rheumatoid arthritis. But now, for the 2 million Americans who suffer from RA, there is the promise of real, lasting relief -- medical miracles discovered on an extraordinary path to a breakthrough. To learn more, see our extensive special report Path to a Breakthrough with Robin Roberts: http://wb.md/2aFICwC
Просмотров: 2721 WebMD
Rheumatoid Arthritis | Biologic Agents for RA | Third Age
 
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Biologic agents interfere with the harmful process of the Rheumatoid Arthritis disease by mimicking the natural substances your body produces on its own. Your doctor will only prescribe a biologic agent if you experienced serious side effects from Disease-Modifying Anti-Rheumatic Drugs (DMARDs) treatment, or if DMARDs failed to effectively control your RA. Enbrel was the first biologic agent available to treat RA, with its properties attaching to Tumor Necrosis Factor (TNF). Newer biologic agents, Humira and Remicade, now directly attack TNF. Kineret attacks receptors on your cells to protect your body from a dangerous substance called interleukin. All biologic agents must be injected, and require different dosing schedules. The positive effects of biologic agents usually appear within 2 to 6 weeks and often have fewer side effects than other RA medication. For information on other RA medication, click the link above.
Просмотров: 13272 Third Age
Rheumatoid Arthritis: Self-Injected Biologics Bring New Freedom
 
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CreakyJoints and the Global Healthy Living Foundation invite you to understand self injected medications with this orientation video for Rheumatoid Arthritis patients. Here, we profile the functional use of auto-injectors, and orient patients and caregivers to their ease. This non-commercial video provides an objective view, utilizing input from medical professionals (doctors, nurse and health psychologist), of how these devices have revolutionized self-injection, including highlighting the benefits of these new innovations. This informative CreakyJoints video dispels the myths of auto-injectors, allays fears and aims to familiarize patients with these devices. Patients who are prescribed an injected biologic for the treatment of Rheumatoid Arthritis (or related autoimmune disease) have questions about their treatment, its mechanism and continue to seek an orientation about the way it works. Medical professionals, including physicians, nurse practitioners and physician assistants have a limited amount of time to orient the patient about the delivery of their medication, and patients are left with unanswered questions. We hope this video serves to orient you and your caregivers about the novel treatments and the innovation that makes self-injection an easy, virtually painless process. Once you have viewed the video, log on to http://www.CreakyJoints.org to discuss your reaction and share your strength and experiences with other members of the CreakyJoints community.
Просмотров: 54694 CreakyJoints
Biologic Therapy | Xeljanz... a new arthritis treatment for rheumatoid arthritis
 
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http://www.arthritistreatmentcenter.com Xeljanz is a new rheumatoid arthritis drug. It is a small molecule drug, meaning it has a different mode of action from all other biologic drugs. It is also oral. Xeljanz has many pluses. But like any new drug, it also has some potential side effects to be on the lookout for. http://youtu.be/5zqlm9_kheU
Просмотров: 6041 Nathan Wei
Biologic Infusions for Rheumatoid Arthritis
 
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How Are The Newest 'Biologic Medications' Used For Rheumatoid Arthritis? This short video is a review of rheumatoid arthritis and the latest treatment methods, by Douglas Roberts MD, Rheumatologist and Assistant Clinical Professor of Medicine and Founder of PainSpot.com, a website to help find and treat more Rheumatoid Arthritis.
Просмотров: 1595 Doug Roberts
The Drug Treatment of Rheumatoid Arthritis Part 1
 
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In this video we firstly discuss the pathology of rheumatoid arthritis and then discuss the pharmacological agents used to teat rheumatoid arthritis.
Просмотров: 25741 Ben1994
Treatment for Rheumatoid Arthritis
 
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Holly Firfer reports on Rheumatoid Arthritis and options for treatment.
Просмотров: 14972 CNN
The Impact of Biologic Therapy on Rheumatoid Arthritis
 
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J. M. van Laar, Editor in Chief of Rheumatology Journal, speaks with Dr. Joachim Listing, of the German Rheumatism Research Centre, about the impact of biologic therapy on functional status in patients with rheumatoid arthritis. http://rheumatology.oxfordjournals.org/
Просмотров: 726 Oxford Academic (Oxford University Press)
Using Biologic Drugs To Treat Rheumatoid Arthritis - Aza Food For Healthy
 
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Using Biologic Drugs To Treat Rheumatoid Arthritis - Aza Food For Healthy Injectable drugs referred to as biologic DMARDs (Disease-Modifying Antirheumatic Drugs)—or simply, biologics—are used to treat rheumatoid arthritis, a chronic condition in which the immune system, which normally fights infection, attacks the lining of the joints, causing swelling, stiffness, and pain Welcome to the Aza Food For Healthy channel, Click this link to subscribe for free channels: https://goo.gl/CYP02v Aza Food for healthy is a channel for healthy foods as: Food for healthy hair, food for healthy heart, food for healthy kid neys ....All will be the best information for your health. Subcribe here: https://goo.gl/CYP02v Follow Aza Food For Healthy on: G+: https://bit.ly/2IlGRDM Facebook: https://bit.ly/2wGnBiW Twitter: https://bit.ly/2jUHRnw Blog: https://bit.ly/2IgOS0S Playlists: - Aza Food for healthy: https://goo.gl/DnxbQ2 - Food good for health: https://goo.gl/gA2rAf - Food is bad for health: https://goo.gl/c8r5zp All Images in the video are illustrative The above video may contain copyrighted material that is based on Fair Use Fair Use Rules (https: //www..com/yt/copyright/fair-use.html). For policy violations, community guidelines, copyright law, please contact us directly via Email: tubetintuc@gmail.com Aza Food for healthy : https://goo.gl/CYP02v ----------------------------------------------------------------------------------------------------------- #Using#Biologic#Drugs#To#Treat#Rheumatoid#Arthritis#Aza#Food#For#Healthy ----------------------------------------------------------------------------------------------------------- source: https://www.consumerreports.org/cro/2013/03/using-biologic-drugs-to-treat-rheumatoid-arthritis/index.htm
Просмотров: 65 Aza Food For Healthy
Biologic Infusions for Rheumatoid Arthritis
 
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How Are The Newest 'Biologic Medications' Used For Rheumatoid Arthritis? This short video is a review of rheumatoid arthritis and the latest treatment methods, by Douglas Roberts MD, Rheumatologist and Assistant Clinical Professor of Medicine and Founder of PainSpot.com, a website to help find and treat more Rheumatoid Arthritis.
Просмотров: 1430 Doug Roberts
Rheumatoid Arthritis
 
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This RA webcast reviews current data and therapeutic approaches. Visit http://www.ccfcme.org/biovcmevideos to claim CME credit or learn more about the Biologic Therapies V series. The rheumatoid arthritis webcast features expert faculty member, Arthur Kavanaugh, MD, of the University of California, San Diego. The video was produced by the Cleveland Clinic Foundation Center for Continuing Education and RJ Fasenmyer Center for Clinical Immunology. Interested in related CME education? Visit http://www.ccfcme.org/rheumcme Like us on Facebook: https://www.facebook.com/CMEClevelandClinic Follow us on Twitter: https://twitter.com/cleveclinic_cme
Просмотров: 935 ClevelandClinicCME
Stem Cell Therapy for Rheumatoid Arthritis | Patient Testimonial
 
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This patient was suffering from rheumatoid arthritis and was treated with RegenMax Injection Therapy at the Regenerative Biologics Institute. After the stem cell treatment she had a substantial reduction in pain and increased mobility in many of her painful joints. RBI is the premier provider of advanced stem cell therapy and platelet rich plasma (or PRP therapy) to residents of Vero Beach, the Treasure Coast and to patients throughout Florida. These procedures are non-surgical and are ultra minimally invasive with little to no recovery time required. Patients walk-in and walk-out of our clinic in about 2 hours. RBI's team has been involved in the treatment of thousands of patients worldwide and has vast experience in developing regenerative therapies. Our expert scientists and clinicians can take a tissue sample from a patient, isolate and concentrate their own regenerative stem cells then inject them into an area of need such as an injured or arthritic joint. Stem cell therapy has been shown to be effective in treating knees, shoulders, hips, spine/back and other areas of the body. Contact RBI today to see if you are a candidate! Phone: 772-492-6973 Email: info@rbistemcell.com Website: www.rbistemcell.com Follow us on social media to stay informed of RBI's latest developments: Facebook: https://www.facebook.com/rbistemcell/ Twitter: https://twitter.com/rbistemcell Advanced Stem Cell Therapy for Osteoarthritis, Orthopedic Conditions and Injuries. Stem Cell Therapy for Arthritis. Stem Cell Therapy for Knees, Shoulders, Ankles, Elbows, Back & Spine and more!
Просмотров: 1033 Regenerative Biologics Institute
Rheumatoid Arthritis Treatment: REMICADE INFUSION
 
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Personal experience receiving Remicade (Infliximab) infusions over last year. Remicade is a TNF-a blocker that works similar to Enbrel, Humira and Simponi. TNF alpha is associated with different types of inflammatory arthritis. Remicade is approved for use for Rheumatoid, Crohn's, Psoriatic Arthritis and other inflammatory autoimmune disorders. www.drugs.com http://www.remicade.com/home?utm_source=google&utm_medium=cpc&utm_campaign=Brand+-+Exact&utm_term=remicade&utm_content=Branded+-+General|mkwid|seZsUhYc6_dc|pcrid|33705340568#safety My diagnosis: Rheumatoid Arthritis (1994) Mixed Connective Tissue Disease - Unspecified (2003) Degenerative Disc Disease (2004) Osteopenia (1996) Somataform Disorder (2008) Major Depressive Disorder (1995) Generalized Anxiety Disorder (1995) PTSD (2010) Chronic Insomnia (1996) Rosacea (2003) Asthma (2008 &2015) Chronic B12 Deficiency (2008) Chronic vitamin D Deficiency (2008) Iron Deficient Anemia (2016)
Просмотров: 6460 Carmen C
New Drug Gives Hope to Rheumatoid Arthritis Patients
 
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Rheumatoid Arthritis often starts during the prime of a person's working life, typically between the age of 35 and 45. Women are 3 times more likely to develop the disease than men. It is an incurable, painful and debilitating auto-immune disease where the body attacks itself, most noticeably in the joints. Methotrexate (MTX) is the current drug prescribed for patients with RA in the UK but if this treatment is not working, patients may also be given a biological drug to help control their disease. However, of the estimated 46,000 RA patients on a biological treatment, 1 in 3 are not taking methotrexate, often because they are intolerant to this treatment. The other most widely prescribed drug is Humira. However a pioneering study has shown fantastic results, among 326 patients, at five trial centres in the UK, which has shown that almost four times as many RA patients achieve complete disease remission taking RoActemra in comparison to Humira for patients who cannot take Methotrexate. Professor Cem Gabey talks about the results of RoActemra. The good news is that at £9,500 per patient per year, RoActemra costs about the same as Humira and The NHS cost-effectiveness watchdog Nice has already approved of RoActemra when combined with methotrexate. It is believed that these new results may lead to the drug being given to larger numbers of patients on its own. Written and Presented by Ann Salter
Просмотров: 3394 IBTimes UK
Biologic DMARDs
 
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Biologic DMARDs presentation from ML 65 and LL 47-- Created using PowToon -- Free sign up at http://www.powtoon.com/youtube/ -- Create animated videos and animated presentations for free. PowToon is a free tool that allows you to develop cool animated clips and animated presentations for your website, office meeting, sales pitch, nonprofit fundraiser, product launch, video resume, or anything else you could use an animated explainer video. PowToon's animation templates help you create animated presentations and animated explainer videos from scratch. Anyone can produce awesome animations quickly with PowToon, without the cost or hassle other professional animation services require.
Просмотров: 8300 Ken Rodgers
Rheumatoid progress discussion - prednisone, NSAIDs, biologic drugs
 
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* Paddison Program for RA http://www.paddisonprogram.com * Get Clint's help http://www.paddisonprogram.com/support
Просмотров: 1945 Paddison Program
Rheumatoid arthritis - causes, symptoms, diagnosis, treatment, pathology
 
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What is rheumatoid arthritis? Rheumatoid arthritis is an autoimmune condition where the immune system attacks the joints. Find more videos at http://osms.it/more. Hundreds of thousands of current & future clinicians learn by Osmosis. We have unparalleled tools and materials to prepare you to succeed in school, on board exams, and as a future clinician. Sign up for a free trial at http://osms.it/more. Subscribe to our Youtube channel at http://osms.it/subscribe. Get early access to our upcoming video releases, practice questions, giveaways, and more when you follow us on social media: Facebook: http://osms.it/facebook Twitter: http://osms.it/twitter Instagram: http://osms.it/instagram Our Vision: Everyone who cares for someone will learn by Osmosis. Our Mission: To empower the world’s clinicians and caregivers with the best learning experience possible. Learn more here: http://osms.it/mission Medical disclaimer: Knowledge Diffusion Inc (DBA Osmosis) does not provide medical advice. Osmosis and the content available on Osmosis's properties (Osmosis.org, YouTube, and other channels) do not provide a diagnosis or other recommendation for treatment and are not a substitute for the professional judgment of a healthcare professional in diagnosis and treatment of any person or animal. The determination of the need for medical services and the types of healthcare to be provided to a patient are decisions that should be made only by a physician or other licensed health care provider. Always seek the advice of a physician or other qualified healthcare provider with any questions you have regarding a medical condition.
Просмотров: 302169 Osmosis
Biologic Medication Infusion Therapy: What to Expect at Your Infusion Visit
 
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Victoria Ruffing, RN, BC-Rheum, Director of Nursing and Patient Education at the Johns Hopkins Arthritis Center walks through what to expect during your first infusion.
Просмотров: 828 Johns Hopkins Rheumatology
Rheumatoid Arthritis and Biologics (रह्युमेटोइड आर्थराइटिस | जैविक दवाइयां)
 
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This video explains what Rheumatoid Arthritis is in Hindi and how it is possible to move from standard treatment to Biologics. English and Hindi subtitles supported. There is a big social stigma around Rheumatoid Arthritis in South Asian communities. Research suggests South Asian people with RA are often forced to hide their condition due to society beliefs, misconceptions etc. Combined with language barriers, this can have a severe impact on their ability to receive accurate info and live a healthy life.
Просмотров: 617 NRAS_UK
Novel Treatments for Rheumatoid Arthritis
 
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Developed and produced for http://www.MechanismsinMedicine.com Animation reviews the novel therapies available for the treatment of rheumatoid arthritis.
Просмотров: 59145 Mechanisms in Medicine
Rheumatoid Arthritis - diagnosis and treatment. How to Cure Rheumatoid Arthritis...
 
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- Juvenile rheumatoid arthritis - Gonarthrosis, coxarthrosis Name, surname – Abdullayeva S., 2003 (DOB) Diagnosis - Juvenile rheumatoid arthritis, hormone-dependent condition, gonarthrosis, coxarthrosis, deformation of the joints of hand and foot phalanxes, contraction of the elbow and hip joints. Treatment: drainage - detoxication – activation of adrenal functions, physiotherapy, rehabilitation, osteopathy, PRP kit therapy, bioregulatory therapy. Joint pain has turned into a "lifetime" companion of both youth and olds. The negative effects of the disease on people's life quality and ability to work also affect the development of the society. This is the reason why world scientists, doctors and researchers are trying to learn more about the causes of joint pain and its treatment ways. In this video we present the girl who suffered from rheumatoid arthritis and her state before and after the treatment. S. Abdudllayeva, born in 2003, who applied the Biological Medicine Clinic and diagnosed with juvenile rheumatoid arthritis, hormone-dependent condition, gonarthrosis, coxarthrosis, deformation of the joints of hand and foot phalanxes, contraction of the elbow and hip joints, regained her health after the treatment. Currently the disease is treated and completely eliminated in the clinic. So let's go behind our health without any delay! Biological Medicine Clinic Tel.: : (+99412) / (+99450) / (+99455) / (+99470) 430 89 89 Address: Baku, Mdst. 3, Str. 110 Peshavari (Str. 24 Cavadkhan), near M. Ajami subway E-mail: info@planeta.az bioklinik@biolojitababat.az YouTube Kanalımız ► https://www.youtube.com/channel/UCmhfatjSOaJzOJxwR7m18kQ Web səhifəmiz ► http://www.btk.az Facebook ► https://www.facebook.com/bioloji.tababat/ Instagram ► https://www.instagram.com/biolojitababat/ Twitter ► https://twitter.com/BTababat #arthritis #rheumatoid #treatment #test #juvenile #examination #arthrosis #arthritis #hormone #inflammation #leg #rheumatologist #long lasting #pains #motion #chronic #deforming #osteoarthrosis #arthrosis #rheumatoid test #rheumatoidfactor #worsenings #virus #infection #joints #disease #handsandfeet #rheumatologist #rheumatoidarthritis
Просмотров: 1221 Bioloji Tebabet
Biologics in RA and Other Rheumatic Diseases
 
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Biologics in RA and Other Rheumatic Diseases webcast reviews immune restoration in rheumatoid arthritis, as well as T reg function. The webcast features expert faculty member, Dr. Leonard Calabrese, of Cleveland Clinic. The video was produced by the Cleveland Clinic Foundation Center for Continuing Education and RJ Fasenmyer Center for Clinical Immunology. Interested in related CME education? Visit http://www.ccfcme.org/rheumcme
Просмотров: 864 ClevelandClinicCME
Use of Biologics in Rheumatoid Arthritis
 
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Stanley B. Cohen, MD, describes the use of biologics to treat rheumatoid arthritis.
Просмотров: 179 Specialty Pharmacy Times
Dr Ved Chaturvedi - When to start biologics Rheumatoid Arthritis?
 
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Dr Ved Chaturvedi - When to start biologics Rheumatoid Arthritis?
Просмотров: 128 Medtalks
Do Biologics Cut Mortality in Rheumatoid Arthritis?
 
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Biologics use by rheumatoid arthritis patients was associated with a 25% reduction in the risk of premature death, compared to patients without exposure to biologics, based on data from a population-based study of more than 4,000 patients. Dr. Diane Lacaille of the Arthritis Research Center of Canada discusses the results at the American College of Rheumatology's annual meeting. See the related story at http://www.rheumatologynews.com
Biologic Infusions for Rheumatoid Arthritis
 
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How Are The Newest 'Biologic Medications' Used For Rheumatoid Arthritis? This short video is a review of rheumatoid arthritis and the latest treatment methods, by Douglas Roberts MD, Rheumatologist and Assistant Clinical Professor of Medicine and Founder of PainSpot.com, a website to help find and treat more Rheumatoid Arthritis.
Просмотров: 217 Doug Roberts
Most Drugs And Medications To Treat Rheumatoid Arthritis
 
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Most Drugs And Medications To Treat Rheumatoid Arthritis 00:00:13 Aspirin 00:01:23 Leflunomide 00:02:14 Methotrexate 00:03:18 Tolmetin 00:04:16 Enbrel
Просмотров: 2424 Home Remedies
Side Effects of Biologic Medications
 
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Vicky Ruffing, RN, shares some useful information on possible side effects when using biological medications.
Просмотров: 1499 Johns Hopkins Rheumatology
Biologic Therapy | RA drugs increase surgical infection risk
 
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http://www.arthritistreatmentcenter.com Surgical Infection Rate Higher with RA Drugs Marianne Wait writing in Arthritis Today reported that people with inflammatory forms of arthritis, such as rheumatoid arthritis, who take more than one traditional disease modifying antirheumatic drug (DMARD), or a type of biologic drug known as a TNF inhibitor, have an increased risk of infection following orthopaedic surgery, according to a new study published in Arthritis Care & Research in December. It is not a new theory that drugs taken for inflammatory arthritis conditions, which in many cases work by suppressing the immune system, might increase post-surgical infections. Over the years, a host of studies has looked at which drugs might elevate the risk and by how much. The results have not been clear. But this study "is one of the best out there regarding this topic," says Tim Bongartz, MD, associate professor of rheumatology at Mayo Clinic in Rochester, Minn. Dr. Bongartz was not involved in the study. Based on their results, senior study author Inès A. Kramers-de Quervain, MD, of the department of rheumatology at the Schulthess Clinic in Zurich, Switzerland, suggests "it may be advisable to consider stopping TNF inhibitors more than one administration interval before surgery, since the risk of postoperative infection appears to be higher if the operation occurs within this period." An administration interval is the length of time between one injection and the next. http://youtu.be/r8g4XsBi-ec
Просмотров: 452 Nathan Wei
Good News for Rheumatoid Arthritis Treatment
 
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www.rxwiki.com Anti-TNFs are a class of drugs commonly used to treat inflammatory conditions like rheumatoid arthritis (RA). But when an anti-TNF fails, what's the next step? In two new studies, a team of researchers from France found that RA patients who don’t respond to initial anti-TNF treatment may achieve better outcomes if they are next prescribed biologic therapy instead of another anti-TNF medication. Studying anti-drug antibodies in these patients may also help guide physicians toward the preferred next step in treatment. "This study demonstrated a better effectiveness of [biologic therapy] than a second anti-TNF for patients who did not respond to their first anti-TNF," said lead study author Jacques-Eric Gottenberg, MD, PhD, of the Department of Rheumatology at Strasbourg University Hospital in France, in a press release. "However, at least 40 percent of patients failed to respond to their second-line biologic, which emphasizes the unmet need to continue to increase the number of treatment options and develop personalized medicine for people with RA."
Просмотров: 754 RxWikiTV
Biologic Therapy | Anti rheumatic drugs don't increase surgical risk
 
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http://www.arthritistreatmentcenter.com Antirheumatic drugs don't increase surgical infection risk Bruce Jancin writing for Skin and Allergy News reported on a study presented at the national meeting of the American College of Rheumatology. Rheumatoid arthritis patients undergoing surgery who stayed on their antirheumatic medication didn't have a higher risk of early postoperative infection compared with those who temporarily stopped treatment before surgery, according to findings from a large national Veterans Affairs study. Until now many rheumatologists and surgeons have taken a conservative approach, reasoning that the immunosuppressive drugs used in controlling inflammation in rheumatoid arthritis might also increase the risk of surgical wound infection. A common practice has been to have RA patients stop their medication a month ahead of elective surgery, or at least two drug half-lives beforehand, then start treatment again roughly a month after the operation, or when the wound has healed. The new Veterans Affairs (VA) study findings suggest this practice may be unnecessary, Dr. Zaki Abou Zahr said. Dr. Bernard Ng, his senior coinvestigator in the study, added that temporarily stopping antirheumatic agents before surgery may actually be harmful in that it increases the risk of a flare of the RA. But there is a major weakness regarding the VA study: Participation was restricted to RA patients on only a single conventional disease-modifying antirheumatic drug (DMARD) or biologic agent leading up to surgery. This restriction, imposed to make for a more clear-cut analysis, means that the study results can't be extrapolated to patients on multidrug therapy. And multidrug therapy is quite common. Comment: Interesting and valuable study http://youtu.be/O24L_AkDBBE
Просмотров: 593 Nathan Wei
Molecule Predicts Whether Biologic Drugs Will Help Individual Rheumatoid Arthritis Patients
 
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A molecule found in the blood is offering a valuable way to predict whether individual rheumatoid arthritis patients are likely to benefit from biologic medications, a Mayo Clinic study shows. Senior author Timothy Niewold, M.D., a Mayo Clinic rheumatologist, says the protein can help physicians prescribe the right medications to each patient, getting their rheumatoid arthritis under control more quickly and sparing them needless side effects and expense. The study was presented at the American College of Rheumatology annual meeting in Boston. For more information, see the Mayo Clinic News Network.
Просмотров: 650 Mayo Clinic
Biologic Therapy | Do biologics for rheumatoid arthritis cause weight gain?
 
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http://www.arthritistreatmentcenter.com Patients are often concerned about the potential side effects of the medicines they take for rheumatoid arthritis. One side effect can be weight gain. Do biologics cause weight gain? In short, no. http://youtu.be/2DJBRZr5eMQ
Просмотров: 827 Nathan Wei
Dr. Lewko speaks about Biologic Arthritis treatments
 
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Get a better understanding of Biologic treatment options for Arthritis & Rheumatology, by Dr. Michael P. Lewko from NJ Arthritis and Osteoporosis Center/St. Joseph's Regional Medical Center
Просмотров: 203 WendyWindmill
Biologic Therapy | How to Banish RA - Humira™
 
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Shrink swollen joints from rheumatoid arthritis almost instantly... Humira Visit http://www.arthritistreatmentcenter.com
Просмотров: 906 Nathan Wei
Biologic Therapy | Biologics cancer 2
 
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http://www.arthritistreatmentcenter.com Do Biologic drugs Increase the risk of cancer? Dr. Jonathan Kay elegantly summarized the answer to this perplexing question on Medscape. He said, "Patients with rheumatoid arthritis appear to be at higher risk of developing lymphoma -- both Hodgkin and non-Hodgkin lymphoma -- and lung cancer, and at a potentially decreased risk of developing colorectal and breast cancer compared with the general population. The risk of developing lymphoma is associated with disease activity and functional class. Patients treated with TNF inhibitors do not have a significantly higher risk of developing malignancy than patients treated with traditional disease-modifying antirheumatic drugs. Treatment of patients who had prior melanoma with TNF inhibitors has been found in the British Society for Rheumatology Biologics Register to have been associated with more incident malignancy and recurrent metastases. The risks associated with biologic agents should be weighed against their potential benefits in patients with previous malignancy as they should be done in any patient with rheumatoid arthritis." Comforting news from a well-respected rheumatologist. http://youtu.be/csDHB_tJMGY
Просмотров: 171 Nathan Wei
Rheumatoid Arthritis | can zoster vaccine be used in ra patients on biologics
 
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http://www.arthritistreatmentcenter.com Is shingles vaccine safe for arthritis patients on biologic therapy? No Extra Risk With Zoster Vax in RA Patients on Biologics Kate Johnson writing for MedPage Today reported herpes zoster vaccination appears to be safe in patients treated with biologic therapies for rheumatoid arthritis (RA), psoriatic arthritis (PsA) and ankylosing spondylitis (AS), despite widespread recommendations against this practice, a new study suggests. Among 176 patients vaccinated against HZ while on biologic therapy, a protocol of withholding one dose of biologic therapy and replacing it with the vaccine has resulted in no complications of disseminated HZ disease and no increased incidence of HZ in the 6-week, post-vaccination window. The practice "appears safe using this protocol," said Stephen Lindsay, MD, Chief of Rheumatology at the Ochsner Clinic. http://youtu.be/XkhNx1Axi6w
Просмотров: 179 Nathan Wei
When Rheumatoid Arthritis Biologics Fail
 
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Rheumatoid arthritis patients who fail on a first-time trial of tumor necrosis factor inhibitor therapy should change to a biologic with a different mechanism of action, explains Dr. Daniel E. Furst. See the related story at http://tinyurl.com/2dz67vx
Biologic Therapy | Anti-TNF treatment lowers risk of heart attack
 
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http://www.arthritistreatmentcenter.com If you're on anti TNF therapy, take heart... Anti-TNF treatment lowers risk of heart attack Sara Freeman writing in Rheumatology News reported on a study from Birmingham England which showed that patients treated with anti-TNF therapy had a 30% lower risk for heart attack than those treated with conventional disease modifying drugs. The hypothesis put forth by the researchers is that by lowering inflammation, these biologic drugs reduce the well- known increased risk for heart attack in rheumatoid arthritis. Comment: Like I said, take heart http://youtu.be/z6y5D6WgPBI
Просмотров: 362 Nathan Wei
Rheumatoid Arthritis: Non-Biologic Therapy and Metrics - Ep. 7
 
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The Rheumatology Highlights Report Series is designed for the busy clinician and provides highlights from key scientific presentations and/or abstracts presented at the most recent national and international rheumatology meetings. The Rheumatoid Arthritis: Non-Biologic Therapy and Metrics webcast presents the most recently presented clinical data on use of non-biologic therapy for rheumatoid arthritis (RA) patients. To learn more about the Rheumatology Highlights Report series or to claim CME credit, visit http://www.ccfcme.org/15minutes The video was produced by the Cleveland Clinic Foundation Center for Continuing Education and the RJ Fasenmyer Center for Clinical Immunology.
Просмотров: 160 ClevelandClinicCME
TNF Inhibitors... what they are and what they do in arthritis treatment
 
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http://www.arthritistreatmentcenter.com Tumor Necrosis Factor (TNF) inhibitors are protein based drugs- often called "biologics"- that are a mainstay of therapy for diseases such as rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. They work in arthritis treatment by blocking a chemical called tumor necrosis factor, which is a major cause of inflammation. They are five currently available TNF inhibitors, 4 administered by subcutaneous injection and one by intravenous injection. All have similar potential side effects. http://youtu.be/jKzr8eLVSQI
Просмотров: 8496 Nathan Wei
Biologic Therapy | Biologics Help With Pain but Not Inflammation.
 
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http://www.arthritistreatmentcenter.com Biologic Drugs help with pain but not inflammation in psoriatic arthritis Nancy Walsh writing in Medpage Today reported on a study presented at the annual meeting of the American College of Rheumatology. "Psoriatic arthritis patients on biologic therapy reported a decrease in pain, but magnetic resonance imaging of their joints showed that there was still active disease," in "29 patients who responded to treatment with Humira, the patient perception of pain dropped markedly," however, bone erosion scores on MRI increased.
Просмотров: 178 Nathan Wei
Rheumatoid Arthritis - Pharmacology
 
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Rheumatoid Arthritis treatments: mechanism of action of DMARDs and bDMARDs.
Просмотров: 6275 pencil sharp
Biologic Therapy | Worrying makes RA worse
 
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http://www.arthritistreatmentcenter.com Do you have rheumatoid arthritis? Do you worry? Be careful... it can make your arthritis worse... Worrying makes RA worse Jennifer Davis writing in Arthritis Today reported, "Patients who have a tendency for more worrying reported slightly more disease activity, more swollen joints and more pain one month later," explains lead author Andrea W. M. Evers, PhD, a clinical psychologist and coordinator at Radboud University Nijmegen Medical Centre in the Netherlands. The researchers were trying to understand how daily stressors and worrying impact symptoms and disease activity in RA, an autoimmune form of arthritis that affects 1.5 million people in the U.S. To find out, they gathered data from 80 RA patients once a month for six months. Patients answered questions about daily stressors (for example, long appointment wait times or losing something valuable), level of worry, and symptoms of pain, fatigue and disease activity. Researchers also took blood samples to measure levels of the stress hormone cortisol as well as inflammatory cytokines (molecules) that are believed to play a key role in RA severity, including TNF-alpha and interleukin-1 beta (IL-1β). (Some biologics, including etanercept (Enbrel) and adalimumab (Humira) are TNF inhibitors, while anakinra (Kineret) is an IL-1 inhibitor.) Researchers found that worrying led to higher self-reported disease activity, more pain and more swollen joints one month later, while daily stressors predicted greater fatigue one month later. They also found that patients with a higher level of certain cytokines -- specifically IL-1β and interferon gamma -- were also likely to experience more fatigue a month later. Comment: Wouldn't it be nice to take a worry pill and make it all go away? http://youtu.be/29QTW6-72Vg
Просмотров: 201 Nathan Wei
Shingles Vaccine Biologics Administration Rheumatoid Arthritis
 
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Shingles vaccine… when to give it… a conundrum Expert advice about shingles vaccine in rheumatoid arthritis Bruca Jancin writing in Rheumatology News reported on a lecture given by Dr. John Cush at the Winter Rheumatology Symposium. While the recommendation is against giving zoster vaccine to patients on biologics, Dr. Cush did a survey of more than 200 patients inadvertently given the vaccine while on biologics. Not one case of shingles occurred. A study conducted in Alabama of 633 patients on biologics given inadvertent zoster vaccine also failed to show an increase in shingles risk and actually showed a 39% reduction in shingles risk. Comment: Reassuring news that shingles vaccine, even though it is live, is not the end of the world if given to patients on biologic therapy. That being said, I still think that a 4 week waiting period before vaccination while holding a biologic is prudent.
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Safety and effectiveness in biological monotherapy in RA - Video abstract [53361]
 
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Video abstract of review paper Biologic monotherapy in the treatment of rheumatoid arthritis published in the open access journal Biologics: Targets and Therapy by Jacqueline Detert and Pascal Klaus. Abstract: Biologics, possibly in combination with a conventional disease-modifying antirheumatic drug (DMARD) – preferably methotrexate (MTX), are used in accordance with the recommendations of the international rheumatological societies. However, in clinical practice, this recommendation is often problematic, as many rheumatologists know from personal experience. The quality of life of the patient is affected mainly by drug-induced intolerances (eg, MTX). Thus, the acceptance of the patient to treatment is often so inadequate that a discontinuation of the drug is necessary. In daily practice, approximately 30% of patients with biological therapy receive no concomitant DMARD according to the register data. Read the full paper here: http://www.dovepress.com/biologic-monotherapy-in-the-treatment-of-rheumatoid-arthritis-peer-reviewed-article-BTT
Просмотров: 216 Dove Medical Press
Biologic Therapy | Do biologic drugs help patients live longer
 
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http://www.arthritistreatmentcenter.com So what about biologic drugs. Do they help RA patients live longer? I treat rheumatoid arthritis aggressively. The reason is that it is a disease that significantly shortens lifespan. Do I have evidence it helps? Sure do and here it is... Heidi Splete writing in Rheumatology News reported on a study from the Canadian Ministry of Health. The study consisted of 4,312 patients. What they found was that exposure to biologic therapy was associated with a 25% reduction in the risk of early death in rheumatoid arthritis patients. http://youtu.be/81c6-cxn8vE
Просмотров: 173 Nathan Wei
Biologic Therapy | Methotrexate™ Alternative?
 
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http://www.arthritistreatmentcenter.com Alternative to Methotrexate... Maybe? Leflunomide (LEF), brand name Arava, offers an alternative with similar effectiveness to Methotrexate (MTX) both by itself as well as in combination with biologic treatment. The addition of Arava to MTX in rheumatoid arthritis patients who have failed MTX by itself has added therapeutic benefit. Safety data on LEF compared to MTX are less conclusive. All patients on LEF, and particularly those on combined LEF+MTX, should be monitored closely for liver toxicity. This last bit needs to be stressed... Arava has been associated with significant liver problems.
Просмотров: 915 Nathan Wei