Patrick C. Walsh, MD, university distinguished service professor of urology, Johns Hopkins School of Medicine, discusses radical prostatectomy operations in the traditional open and robotic-assisted form.
Просмотров: 4691 OncLiveTV
In this segment, H. Jack West, MD, discusses the dramatic benefit seen by some patients with non-small cell lung cancer who receive treatment with nivolumab. For more from this discussion, visit http://www.onclive.com/peer-exchange/nsclc-needs
Просмотров: 6227 OncLiveTV
Sundar Jagannath, MD, Director, Multiple Myeloma Program, The Tisch Cancer Institute at The Mount Sinai Medical Center, details the advances in life expectancy for patients with multiple myeloma. For more hematology resources: http://www.onclive.com/specialty/hematologic-cancer
Просмотров: 6716 OncLiveTV
Moderator Myron Czuczman, MD, leads experts in a discussion about selecting first-line therapy for varied subgroups with CLL, and recognizing the shift from the traditional chemotherapy regimens to the incorporation of newly approved anti-CD20 antibodies.
Просмотров: 6436 OncLiveTV
Dr. Leonard Gomella talks about when he would choose to use abiraterone or enzalutamide for his metastatic prostate cancer patients. The AR-V7 spice variant as a marker for resistance against these drugs is an exciting new development! View more, at http://www.onclive.com/inside-oncology
Просмотров: 3778 OncLiveTV
Rodney F. Pommier, MD, discusses surgical debulking and embolization for the treatment of hepatic metastases in patients with pancreatic neuroendocrine tumors. To view more from this discussion, visit http://www.onclive.com/peer-exchange/pancreatic-nets
Просмотров: 6905 OncLiveTV
Keith Stewart, MB, ChB; Saad Z. Usmani, MD; Thomas G. Martin, MD; Sagar Lonial, MD; Ivan M. Borrello, MD; and Gareth Morgan, MD, PhD, highlight trials that are reviewing the potential use of chimeric antigen receptor T-cell therapy that targets the protein, B-cell maturation antigen in multiple myeloma.
Просмотров: 1908 OncLiveTV
Panelists William D. Tap, MD; Damon Reed, MD; George D. Demetri, MD; Martee L. Hensley, MD; Mark Agulnik, MD; and Shreyaskumar Patel, MD, discuss the challenges in determining an accurate diagnosis and treatment approach in soft tissue sarcoma, as well as the most common and most aggressive soft tissue sarcoma subtypes.
Просмотров: 12447 OncLiveTV
Amy Robach, breast cancer survivor and Good Morning America news anchor, discusses her choice to have a bilateral mastectomy against the advice of her surgical oncologist.
Просмотров: 6096 OncLiveTV
Panelists Bradley J. Monk, MD; Thomas Herzog, MD; Robert L. Coleman, MD; Kathleen N. Moore, MD; and Angeles Alvarez Secord, MD, discuss the data for niraparib, the emerging PARP inhibitor, in advanced ovarian cancer.
Просмотров: 3665 OncLiveTV
Panelists Jeffrey S. Weber, MD, PhD; Georgina Long, MD, PhD; Jason J. Luke, MD; Robert H.I. Andtbacka, MD, CM; and Michael A. Davies, MD, PhD, discuss the data looking at long-term use of CTLA-4 and PD-1 antibodies in metastatic melanoma and the implications for outcomes after stopping therapy.
Просмотров: 3444 OncLiveTV
In this segment, Jennifer Brown, MD, and Richard Furman, MD, review adverse events associated with ibrutinib therapy in the treatment of chronic lymphocytic leukemia (CLL).
Просмотров: 6389 OncLiveTV
In the final case study of the discussion, panelists describe the treatment of a 58 year-old Caucasian woman with metastatic triple-negative breast cancer. To view more from this discussion, visit http://www.onclive.com/peer-exchange/MBC-challenges
Просмотров: 2587 OncLiveTV
Steven A. Rosenberg, MD, PhD, Chief of Surgery, National Cancer Institute, Professor of Surgery, Uniformed Services University of Health Sciences and the George Washington University School of Medicine and Health Sciences, Giant of Cancer Care, discusses the curative potential of cancer immunotherapy.
Просмотров: 2067 OncLiveTV
In this segment, panelists discuss the diagnosis and primary treatment for patients with medullary thyroid cancer. To view more from this discussion, visit http://www.onclive.com/peer-exchange/thyroid-cancer
Просмотров: 2346 OncLiveTV
Jason J. Luke, MD, assistant professor of Medicine, The University of Chicago Medicine, discusses the controversy surrounding the combination of nivolumab (Opdivo) and ipilimumab (Yervoy) in treatment-naïve patients with advanced melanoma, which was explored in the CheckMate-067 trial, during the AACR Annual Meeting. The combination gained regulatory approval based on response rate and progression-free survival, with the assumption that those results would translate to overall survival (OS), Luke explains. Results of the CheckMate-067 study, reported at AACR, confirmed there was a 12% improvement in OS, however, there is still a question of whether the OS improvement justifies the extreme increase in toxicity with the addition of ipilimumab, relative to PD-1 monotherapy. While doctors continue to have differing opinions on the subject, Luke says his group is interested in exploring how to maximize benefit and minimize toxicity. One possible way to do this is with IDO inhibitor combinations, Luke says, for example, leading in with a PD-1 combination with high efficacy and low toxicity, and then using a CTLA-4 or ipilimumab-based regimen in the second-line setting if a patient progresses.
Просмотров: 1411 OncLiveTV
The panelists, John L. Marshall, MD; Johanna Bendell, MD; Charles S. Fuchs, MD, MPH; Tanios Bekaii-Saab, MD; and Richard Kim, MD, discuss how they decide between the chemotherapy regimens FOLFOX and FOLFIRI in colorectal cancer.
Просмотров: 3111 OncLiveTV
The panelists, John L. Marshall, MD; Johanna Bendell, MD; Tanios Bekaii-Saab, MD; Charles S. Fuchs, MD, MPH; and Richard Kim, MD, discuss the value of microsatellite instability (MSI) testing and access to appropriate treatment in colorectal cancer.
Просмотров: 1851 OncLiveTV
Marwan Fakih, MD, outlines several factors to consider when determining the appropriateness and feasibility of liver resectability.
Просмотров: 712 OncLiveTV
In this segment, Howard A. Liebman, MD; Ivy Altomare, MD; and Keith McCrae, MD, explain the use of splenectomy as a treatment for idiopathic thrombocytopenic purpura (ITP).
Просмотров: 1793 OncLiveTV
In this segment, panelists discuss immunotherapy combinations that have generated excitement as treatments for patients with melanoma, specifically those looking at the PD-1 and CTLA-4 inhibitors. To view more from this discussion, visit http://www.onclive.com/peer-exchange/metastatic-melanoma
Просмотров: 3853 OncLiveTV
In this segment, the panelists discuss whether or not the administration of BCR-ABL-targeted TKIs should ever be stopped for patients with CML experiencing a complete molecular response. To view more from this discussion, visit http://www.onclive.com/peer-exchange/mds-cml
Просмотров: 3483 OncLiveTV
Brian Van Tine, MD, PhD, leads the discussion about the diagnostic workup of a new patient, the usefulness of imaging and genetic testing, and the importance of multidisciplinary care. A good history and physical is the most important test we order, according to Lor Randall, MD, FACS.
Просмотров: 5281 OncLiveTV
Panelists Bradley J. Monk, MD; Angeles Alvarez Secord, MD; Robert L. Coleman, MD; Thomas Herzog, MD; and Kathleen N. Moore, MD, outline the clinical evidence for the use of the PARP inhibitor, niraparib, in advanced ovarian cancer.
Просмотров: 1639 OncLiveTV
James M. Foran, MD, FRCPC, and Azra Raza, MD, discuss the common disease characteristics with MDS and drivers of disease progression.
Просмотров: 1261 OncLiveTV
Panelists discuss the use of obinutuzumab, including the results of the CLL 11 clinical trial, early experiences with patient response, and side effects.
Просмотров: 2970 OncLiveTV
Eric Liu, MD, FACS, surgeon, neuroendocrine tumors, Rocky Mountain Cancer Centers, discusses some of the most recent medical advancements in the field of neuroendocrine tumors.
Просмотров: 1375 OncLiveTV
Marcia S. Brose, MD, PhD, presents a case study focused on a women diagnosed with papillary thyroid cancer at age 35 who went on to receive systemic therapy. For more from this discussion, visit http://www.onclive.com/peer-exchange/thyroid-cancer
Просмотров: 2780 OncLiveTV
Kim Chi, MD, associate director of clinical research, Vancouver Prostate Centre, professor, Department of Medicine, University of British Columbia, discusses a study investigating abiraterone acetate (Zytiga) versus enzalutamide (Xtandi) for patients with metastatic castration-resistant prostate cancer (mCRPC).
Просмотров: 892 OncLiveTV
Jan S. Lewin, PhD, professor, Department of Head and Neck Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, discusses the impact of lymphedema in patients with head and neck cancer.
Просмотров: 1020 OncLiveTV
Julia White, MD, professor of Radiation Oncology, Ohio State University Comprehensive Cancer Center, discusses the omission of radiation therapy for patients with breast cancer. Omitting radiation in this space requires finding a population of patients that has a low enough overall risk following lumpectomy, says White. The omission of radiation will leave patients with a slightly higher locoregional recurrence risk than if they had been radiated or had undergone a mastectomy. The omission of radiation in younger patients with breast cancer. This is a bit harder, says White, because there are some subgroups of patients that can have quite high recurrence risks. Biologic selection criteria can be used along with the basic, clinical pathologic criteria to find a group of patients who may, indeed, have a slightly higher risk of local recurrence, but whose overall survival will not be significantly affected.
Просмотров: 1134 OncLiveTV
Srdan Verstovsek, MD, PhD, and Daniel J. DeAngelo, MD, PhD, discuss heterogeneity and progression in myelofibrosis, including disease characteristics, rapid progression, and morbidity and mortality.
Просмотров: 2045 OncLiveTV
Joanne Blum, MD, PhD, and Adam Brufsky, MD, PhD, discuss eribulin as a treatment of patients with metastatic breast cancer. For more expert insight, visit http://www.onclive.com/insights/evolution-metastatic-breast-cancer
Просмотров: 1085 OncLiveTV